Avoro Capital Advisors LLC Buys Acceleron Pharma Inc, Apellis Pharmaceuticals Inc, Aadi Bioscience Inc, Sells , Relmada Therapeutics Inc, Syndax Pharmaceuticals Inc

• New Purchases: AADI, KYMR, DICE, BIIB, NUVL, TNGX,
• Added Positions: XLRN, APLS, FOLD, PMVP, BMRN, RNA, ASND, ISEE, SRPT, MNKD,
• Reduced Positions: ARNA, ALNY, VRTX, SNDX, IOVA, AVDL, ACAD, MRUS, KURA,
• Sold Out: CNST, RLMD, OLMA, CNTA, BCTG, ADAP, ARPO,

For the details of Avoro Capital Advisors LLC's stock buys and sells, go to https://www.gurufocus.com/guru/avoro+capital+advisors+llc/current-portfolio/portfolio

1. Horizon Therapeutics PLC (HZNP) - 9,000,000 shares, 15.49% of the total portfolio.
2. Mirati Therapeutics Inc (MRTX) - 5,000,000 shares, 13.89% of the total portfolio.
3. Acceleron Pharma Inc (XLRN) - 4,000,000 shares, 10.81% of the total portfolio. Shares added by 33.33%
4. United Therapeutics Corp (UTHR) - 3,000,000 shares, 8.70% of the total portfolio.
5. Ascendis Pharma A/S (ASND) - 1,980,000 shares, 4.96% of the total portfolio. Shares added by 4.21%

Avoro Capital Advisors LLC initiated holding in Aadi Bioscience Inc. The purchase prices were between $0 and $32.66, with an estimated average price of $27.53. The stock is now traded at around $23.520000. The impact to a portfolio due to this purchase was 0.84%. The holding were 1,829,402 shares as of 2021-09-30.

Avoro Capital Advisors LLC initiated holding in Kymera Therapeutics Inc. The purchase prices were between $47.8 and $66.66, with an estimated average price of $57.98. The stock is now traded at around $61.620000. The impact to a portfolio due to this purchase was 0.42%. The holding were 455,750 shares as of 2021-09-30.

Avoro Capital Advisors LLC initiated holding in DICE Therapeutics Inc. The purchase prices were between $31.92 and $37, with an estimated average price of $34.06. The stock is now traded at around $31.160000. The impact to a portfolio due to this purchase was 0.41%. The holding were 800,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC initiated holding in Biogen Inc. The purchase prices were between $282.99 and $369.05, with an estimated average price of $328.16. The stock is now traded at around $273.240000. The impact to a portfolio due to this purchase was 0.37%. The holding were 84,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC initiated holding in Nuvalent Inc. The purchase prices were between $18.25 and $38.35, with an estimated average price of $29.21. The stock is now traded at around $23.980000. The impact to a portfolio due to this purchase was 0.35%. The holding were 1,257,671 shares as of 2021-09-30.

Avoro Capital Advisors LLC initiated holding in Tango Therapeutics Inc. The purchase prices were between $9.56 and $17.3, with an estimated average price of $13.13. The stock is now traded at around $13.510000. The impact to a portfolio due to this purchase was 0.31%. The holding were 1,550,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC added to a holding in Acceleron Pharma Inc by 33.33%. The purchase prices were between $115.25 and $182.78, with an estimated average price of $130.74. The stock is now traded at around $173.981100. The impact to a portfolio due to this purchase was 2.7%. The holding were 4,000,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC added to a holding in Apellis Pharmaceuticals Inc by 397.40%. The purchase prices were between $31.4 and $69.84, with an estimated average price of $56.51. The stock is now traded at around $42.200000. The impact to a portfolio due to this purchase was 2.07%. The holding were 5,000,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC added to a holding in Amicus Therapeutics Inc by 42.00%. The purchase prices were between $8.74 and $11.84, with an estimated average price of $10.24. The stock is now traded at around $11.805000. The impact to a portfolio due to this purchase was 0.78%. The holding were 17,679,273 shares as of 2021-09-30.

Avoro Capital Advisors LLC added to a holding in PMV Pharmaceuticals Inc by 60.27%. The purchase prices were between $26.84 and $36.58, with an estimated average price of $31.89. The stock is now traded at around $24.440000. The impact to a portfolio due to this purchase was 0.52%. The holding were 2,925,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC added to a holding in Avidity Biosciences Inc by 111.01%. The purchase prices were between $18.16 and $25.21, with an estimated average price of $21.73. The stock is now traded at around $24.840000. The impact to a portfolio due to this purchase was 0.23%. The holding were 1,150,000 shares as of 2021-09-30.

Avoro Capital Advisors LLC sold out a holding in . The sale prices were between $33.9 and $33.99, with an estimated average price of $33.95.

Avoro Capital Advisors LLC sold out a holding in Relmada Therapeutics Inc. The sale prices were between $21.86 and $34.77, with an estimated average price of $26.82.

Avoro Capital Advisors LLC sold out a holding in Olema Pharmaceuticals inc. The sale prices were between $22.96 and $30.13, with an estimated average price of $27.02.

Avoro Capital Advisors LLC sold out a holding in Centessa Pharmaceuticals PLC. The sale prices were between $16.7 and $23.11, with an estimated average price of $20.76.

Avoro Capital Advisors LLC sold out a holding in BCTG Acquisition Corp. The sale prices were between $9.88 and $11.33, with an estimated average price of $10.53.

Avoro Capital Advisors LLC sold out a holding in Adaptimmune Therapeutics PLC. The sale prices were between $3.44 and $6.37, with an estimated average price of $4.49.