Baker Bros. Advisors Lp Buys Seagen Inc, AbCellera Biologics Inc, Invitae Corp, Sells Seagen Inc, MyoKardia Inc, Exact Sciences Corp

• New Purchases: SGEN, ABCL, RARE, ALGS, UKJ2, VSTM, MREO, FPRX, KDNY, MGNX, TCDA, GOSS, LOGC, RYIS,
• Added Positions: KOD, NVTA, RETA, ADAP, GMDA, FMTX, CRNX, GTH, ALKS, AUTL, ALLK, MIRM, OVID,
• Reduced Positions: BGNE, AMRN, AXSM, CCXI, ADCT, QURE, AGLE, HRMY, ALBO, HZNP, ALT, REPL, KZR, RYTM, ADPT, KRYS, FLGT, PTGX, FREQ, ATHA, INSM, AUPH, CBAY, XNCR, NVAX, GWPH, ORTX, INFI, ALEC, TCRR, GNFT, NGM, AKRO, SGMO, KRTX, VXRT, OYST, PASG, LEGN, BNR, INZY, DRNA, BLUE, GLMD, ADMS, AFMD, VKTX, XENE, EVFM, XLRN, NTLA, MTEM, ANAB, PACB, GLPG, IFRX, DNLI, RCUS, CNST,
• Sold Out: SGT, MYOK, EXAS, IMMU, UROV, CPRX, SNSS, ARAV, APLT,

For the details of BAKER BROS. ADVISORS LP's stock buys and sells, go to https://www.gurufocus.com/guru/baker+bros.+advisors+lp/current-portfolio/portfolio

1. Seagen Inc (SGEN) - 47,269,424 shares, 31.37% of the total portfolio. New Position
2. BeiGene Ltd (BGNE) - 11,668,897 shares, 11.43% of the total portfolio. Shares reduced by 12.27%
3. Incyte Corp (INCY) - 31,999,741 shares, 10.55% of the total portfolio.
4. ACADIA Pharmaceuticals Inc (ACAD) - 41,904,586 shares, 8.49% of the total portfolio.
5. Kodiak Sciences Inc (KOD) - 13,879,952 shares, 7.73% of the total portfolio. Shares added by 12.37%

Baker Bros. Advisors Lp initiated holding in Seagen Inc. The purchase prices were between $164.63 and $211.93, with an estimated average price of $186.26. The stock is now traded at around $159.340000. The impact to a portfolio due to this purchase was 31.37%. The holding were 47,269,424 shares as of 2020-12-31.

Baker Bros. Advisors Lp initiated holding in AbCellera Biologics Inc. The purchase prices were between $39 and $58.9, with an estimated average price of $45.73. The stock is now traded at around $44.040000. The impact to a portfolio due to this purchase was 1.59%. The holding were 10,450,180 shares as of 2020-12-31.

Baker Bros. Advisors Lp initiated holding in Ultragenyx Pharmaceutical Inc. The purchase prices were between $84.4 and $177.39, with an estimated average price of $119.15. The stock is now traded at around $144.340000. The impact to a portfolio due to this purchase was 0.23%. The holding were 444,444 shares as of 2020-12-31.

Baker Bros. Advisors Lp initiated holding in Aligos Therapeutics Inc. The purchase prices were between $13.2 and $32.74, with an estimated average price of $19.48. The stock is now traded at around $30.560000. The impact to a portfolio due to this purchase was 0.17%. The holding were 1,610,000 shares as of 2020-12-31.

Baker Bros. Advisors Lp initiated holding in Opthea Ltd. The purchase prices were between $9 and $11.46, with an estimated average price of $10.49. The stock is now traded at around $9.000000. The impact to a portfolio due to this purchase was 0.14%. The holding were 3,308,705 shares as of 2020-12-31.

Baker Bros. Advisors Lp initiated holding in Mereo BioPharma Group PLC. The purchase prices were between $1.95 and $3.6, with an estimated average price of $2.5. The stock is now traded at around $3.480000. The impact to a portfolio due to this purchase was 0.08%. The holding were 6,030,293 shares as of 2020-12-31.

Baker Bros. Advisors Lp added to a holding in Invitae Corp by 32.05%. The purchase prices were between $39.09 and $57.4, with an estimated average price of $47.83. The stock is now traded at around $49.070000. The impact to a portfolio due to this purchase was 0.6%. The holding were 15,649,182 shares as of 2020-12-31.

Baker Bros. Advisors Lp added to a holding in Reata Pharmaceuticals Inc by 321.14%. The purchase prices were between $102.03 and $184.62, with an estimated average price of $131.85. The stock is now traded at around $124.390000. The impact to a portfolio due to this purchase was 0.08%. The holding were 223,976 shares as of 2020-12-31.

Baker Bros. Advisors Lp added to a holding in Adaptimmune Therapeutics PLC by 55.30%. The purchase prices were between $4 and $9.2, with an estimated average price of $5.39. The stock is now traded at around $6.770000. The impact to a portfolio due to this purchase was 0.07%. The holding were 9,830,877 shares as of 2020-12-31.

Baker Bros. Advisors Lp added to a holding in Gamida Cell Ltd by 144.47%. The purchase prices were between $4.07 and $11, with an estimated average price of $6.81. The stock is now traded at around $11.240000. The impact to a portfolio due to this purchase was 0.03%. The holding were 1,548,314 shares as of 2020-12-31.

Baker Bros. Advisors Lp added to a holding in Crinetics Pharmaceuticals Inc by 103.93%. The purchase prices were between $12.08 and $17.46, with an estimated average price of $13.91. The stock is now traded at around $15.670000. The impact to a portfolio due to this purchase was 0.02%. The holding were 616,520 shares as of 2020-12-31.

Baker Bros. Advisors Lp added to a holding in Genetron Holdings Ltd by 355.31%. The purchase prices were between $9.31 and $14, with an estimated average price of $12.08. The stock is now traded at around $27.770000. The impact to a portfolio due to this purchase was 0.02%. The holding were 455,306 shares as of 2020-12-31.

Baker Bros. Advisors Lp sold out a holding in Seagen Inc. The sale prices were between $138.28 and $179.9, with an estimated average price of $155.92.

Baker Bros. Advisors Lp sold out a holding in MyoKardia Inc. The sale prices were between $139.6 and $224.91, with an estimated average price of $220.55.

Baker Bros. Advisors Lp sold out a holding in Exact Sciences Corp. The sale prices were between $99.61 and $142.12, with an estimated average price of $121.18.

Baker Bros. Advisors Lp sold out a holding in Immunomedics Inc. The sale prices were between $85.08 and $87.86, with an estimated average price of $86.65.

Baker Bros. Advisors Lp sold out a holding in Urovant Sciences Ltd. The sale prices were between $7.39 and $16.19, with an estimated average price of $12.44.

Baker Bros. Advisors Lp sold out a holding in Catalyst Pharmaceuticals Inc. The sale prices were between $2.97 and $3.83, with an estimated average price of $3.36.