Avidity Partners Management LP Buys Intuitive Surgical Inc, Medtronic PLC, Seagen Inc, Sells Eli Lilly and Co, Quest Diagnostics Inc, Biomarin Pharmaceutical Inc

• New Purchases: ISRG, SGEN, NUVB, ALNY, ZBH, BBIO, ABMD, INO, IDYA, CI, ORTX, CGEM, ACET, SANA, CMRX, BVS, PHAS, KZR, PHVS, ADMS, MRUS, AFMD, IMTX, EVLO, CMLF, ARGX, MSACU, HLXA, EYPT,
• Added Positions: MDT, ABBV, AZN, EXAS, CAH, BHVN, VRTX, BPMC, CTLT, NBIX, ARNA, MRTX, IGMS, ALDX, HARP, SNDX, ATHA, SHC, STTK, CCXI, TRIL, EPIX, ATEC, CRDF, ONCS, KNSA, ZNTL, BLU, SGTX, XLRN, ALPN, AMWL,
• Reduced Positions: AVTR, HZNP, ORGO, MRVI, IMAB, COLL, NTRA, AUPH, ARVN, CRIS, DVAX, BHC, SIBN, COGT,
• Sold Out: LLY, DGX, BMRN, CHNG, APLS, SRPT, ANIK, ACAD, ZYME, BTAI, ATRC, NTLA, SGRY, RETA, CERT, STRO, CDXS, OLMA, KURA, TSHA, CSTL, OSH, LGND, OM, OCUL, PHAT, FPRX, ALBO, KROS, RCKT, ACCD, RLAY, INZY,

For the details of Avidity Partners Management LP's stock buys and sells, go to https://www.gurufocus.com/guru/avidity+partners+management+lp/current-portfolio/portfolio

1. AbbVie Inc (ABBV) - 2,077,200 shares, 6.45% of the total portfolio. Shares added by 53.19%
2. AstraZeneca PLC (AZN) - 3,650,500 shares, 5.21% of the total portfolio. Shares added by 58.72%
3. Avantor Inc (AVTR) - 4,985,100 shares, 4.14% of the total portfolio. Shares reduced by 24.09%
4. Medtronic PLC (MDT) - 1,024,200 shares, 3.47% of the total portfolio. Shares added by 240.27%
5. Arvinas Inc (ARVN) - 1,760,300 shares, 3.34% of the total portfolio. Shares reduced by 1.51%

Avidity Partners Management LP initiated holding in Intuitive Surgical Inc. The purchase prices were between $684.9 and $818.75, with an estimated average price of $755.6. The stock is now traded at around $821.450000. The impact to a portfolio due to this purchase was 2.95%. The holding were 139,400 shares as of 2021-03-31.

Avidity Partners Management LP initiated holding in Seagen Inc. The purchase prices were between $137.51 and $190.8, with an estimated average price of $161.21. The stock is now traded at around $148.400000. The impact to a portfolio due to this purchase was 2.3%. The holding were 577,900 shares as of 2021-03-31.

Avidity Partners Management LP initiated holding in Nuvation Bio Inc. The purchase prices were between $9 and $14.57, with an estimated average price of $11.15. The stock is now traded at around $11.590000. The impact to a portfolio due to this purchase was 2.25%. The holding were 7,521,941 shares as of 2021-03-31.

Avidity Partners Management LP initiated holding in Alnylam Pharmaceuticals Inc. The purchase prices were between $126.83 and $175.69, with an estimated average price of $150.61. The stock is now traded at around $135.600000. The impact to a portfolio due to this purchase was 1.73%. The holding were 427,969 shares as of 2021-03-31.

Avidity Partners Management LP initiated holding in Zimmer Biomet Holdings Inc. The purchase prices were between $152.6 and $164.5, with an estimated average price of $159.58. The stock is now traded at around $166.280000. The impact to a portfolio due to this purchase was 1.5%. The holding were 326,000 shares as of 2021-03-31.

Avidity Partners Management LP initiated holding in BridgeBio Pharma Inc. The purchase prices were between $55.47 and $72.35, with an estimated average price of $65.45. The stock is now traded at around $52.700000. The impact to a portfolio due to this purchase was 1.44%. The holding were 815,100 shares as of 2021-03-31.

Avidity Partners Management LP added to a holding in Medtronic PLC by 240.27%. The purchase prices were between $111.18 and $119.74, with an estimated average price of $117.24. The stock is now traded at around $125.480000. The impact to a portfolio due to this purchase was 2.45%. The holding were 1,024,200 shares as of 2021-03-31.

Avidity Partners Management LP added to a holding in AbbVie Inc by 53.19%. The purchase prices were between $102.3 and $112.62, with an estimated average price of $106.92. The stock is now traded at around $117.070000. The impact to a portfolio due to this purchase was 2.24%. The holding were 2,077,200 shares as of 2021-03-31.

Avidity Partners Management LP added to a holding in AstraZeneca PLC by 58.72%. The purchase prices were between $47.16 and $54.44, with an estimated average price of $50.29. The stock is now traded at around $55.640000. The impact to a portfolio due to this purchase was 1.93%. The holding were 3,650,500 shares as of 2021-03-31.

Avidity Partners Management LP added to a holding in Exact Sciences Corp by 142.11%. The purchase prices were between $116.57 and $155.01, with an estimated average price of $137.18. The stock is now traded at around $93.970000. The impact to a portfolio due to this purchase was 1.33%. The holding were 598,000 shares as of 2021-03-31.

Avidity Partners Management LP added to a holding in Cardinal Health Inc by 81.06%. The purchase prices were between $51.37 and $62.46, with an estimated average price of $55.14. The stock is now traded at around $56.090000. The impact to a portfolio due to this purchase was 1.14%. The holding were 1,463,000 shares as of 2021-03-31.

Avidity Partners Management LP added to a holding in Biohaven Pharmaceutical Holding Co Ltd by 113.46%. The purchase prices were between $64.07 and $91.75, with an estimated average price of $80.92. The stock is now traded at around $68.780000. The impact to a portfolio due to this purchase was 1.09%. The holding were 1,049,800 shares as of 2021-03-31.

Avidity Partners Management LP sold out a holding in Eli Lilly and Co. The sale prices were between $164.32 and $212.72, with an estimated average price of $195.8.

Avidity Partners Management LP sold out a holding in Quest Diagnostics Inc. The sale prices were between $114.63 and $133.34, with an estimated average price of $123.27.

Avidity Partners Management LP sold out a holding in Biomarin Pharmaceutical Inc. The sale prices were between $74.73 and $90.69, with an estimated average price of $81.78.

Avidity Partners Management LP sold out a holding in Change Healthcare Inc. The sale prices were between $18.24 and $24.14, with an estimated average price of $23.16.

Avidity Partners Management LP sold out a holding in Apellis Pharmaceuticals Inc. The sale prices were between $40.8 and $57.39, with an estimated average price of $47.3.

Avidity Partners Management LP sold out a holding in Sarepta Therapeutics Inc. The sale prices were between $72.25 and $168.95, with an estimated average price of $92.26.