Frazier Management Llc Buys Imago BioSciences Inc, Gritstone Bio Inc, Viridian Therapeutics Inc, Sells , Alpine Immune Sciences Inc, Regenxbio Inc

• New Purchases: IMGO, VRDN, TYRA, BCYC, CRNX, REPL, GRCL, KALV,
• Added Positions: GRTS, IOVA, SRRA, STRO, AUTL, KDNY, AVDL, IMVT, ACRS, EPIX,
• Reduced Positions: ALPN, RGNX, ISEE, BLU, KRYS,
• Sold Out: TBIO,

For the details of FRAZIER MANAGEMENT LLC's stock buys and sells, go to https://www.gurufocus.com/guru/frazier+management+llc/current-portfolio/portfolio

1. Arcutis Biotherapeutics Inc (ARQT) - 8,434,232 shares, 16.12% of the total portfolio.
2. Phathom Pharmaceuticals Inc (PHAT) - 5,827,415 shares, 14.97% of the total portfolio.
3. Mirum Pharmaceuticals Inc (MIRM) - 3,566,912 shares, 5.69% of the total portfolio.
4. Iovance Biotherapeutics Inc (IOVA) - 2,674,299 shares, 5.28% of the total portfolio. Shares added by 25.08%
5. Imago BioSciences Inc (IMGO) - 2,971,274 shares, 4.76% of the total portfolio. New Position

Frazier Management Llc initiated holding in Imago BioSciences Inc. The purchase prices were between $16 and $28.84, with an estimated average price of $21.56. The stock is now traded at around $25.560000. The impact to a portfolio due to this purchase was 4.76%. The holding were 2,971,274 shares as of 2021-09-30.

Frazier Management Llc initiated holding in Viridian Therapeutics Inc. The purchase prices were between $10.69 and $18.2, with an estimated average price of $14.67. The stock is now traded at around $18.500000. The impact to a portfolio due to this purchase was 1.98%. The holding were 1,505,200 shares as of 2021-09-30.

Frazier Management Llc initiated holding in Tyra Biosciences Inc. The purchase prices were between $16.91 and $26, with an estimated average price of $19.11. The stock is now traded at around $27.310000. The impact to a portfolio due to this purchase was 1.76%. The holding were 1,250,000 shares as of 2021-09-30.

Frazier Management Llc initiated holding in Bicycle Therapeutics PLC. The purchase prices were between $27.95 and $44.24, with an estimated average price of $35.01. The stock is now traded at around $56.825000. The impact to a portfolio due to this purchase was 1.47%. The holding were 442,880 shares as of 2021-09-30.

Frazier Management Llc initiated holding in Crinetics Pharmaceuticals Inc. The purchase prices were between $16.88 and $25.23, with an estimated average price of $20.96. The stock is now traded at around $26.950000. The impact to a portfolio due to this purchase was 1.43%. The holding were 851,306 shares as of 2021-09-30.

Frazier Management Llc initiated holding in Replimune Group Inc. The purchase prices were between $28.98 and $39.54, with an estimated average price of $32.59. The stock is now traded at around $33.790000. The impact to a portfolio due to this purchase was 1.17%. The holding were 491,998 shares as of 2021-09-30.

Frazier Management Llc added to a holding in Gritstone Bio Inc by 352.74%. The purchase prices were between $6.41 and $13.54, with an estimated average price of $9.12. The stock is now traded at around $11.020000. The impact to a portfolio due to this purchase was 3.14%. The holding were 4,667,242 shares as of 2021-09-30.

Frazier Management Llc added to a holding in Iovance Biotherapeutics Inc by 25.08%. The purchase prices were between $20.35 and $26.63, with an estimated average price of $23.63. The stock is now traded at around $20.470000. The impact to a portfolio due to this purchase was 1.06%. The holding were 2,674,299 shares as of 2021-09-30.

Frazier Management Llc added to a holding in Sierra Oncology Inc by 296.77%. The purchase prices were between $16.4 and $23.1, with an estimated average price of $19.99. The stock is now traded at around $22.199500. The impact to a portfolio due to this purchase was 1.05%. The holding were 804,667 shares as of 2021-09-30.

Frazier Management Llc added to a holding in Sutro Biopharma Inc by 46.66%. The purchase prices were between $16.88 and $22.38, with an estimated average price of $19.05. The stock is now traded at around $19.210000. The impact to a portfolio due to this purchase was 0.71%. The holding were 1,468,663 shares as of 2021-09-30.

Frazier Management Llc added to a holding in Autolus Therapeutics PLC by 54.58%. The purchase prices were between $5.32 and $7.37, with an estimated average price of $6.34. The stock is now traded at around $6.610000. The impact to a portfolio due to this purchase was 0.65%. The holding were 3,530,657 shares as of 2021-09-30.

Frazier Management Llc added to a holding in Chinook Therapeutics Inc by 51.99%. The purchase prices were between $11.5 and $14.86, with an estimated average price of $13.17. The stock is now traded at around $16.140000. The impact to a portfolio due to this purchase was 0.58%. The holding were 1,671,918 shares as of 2021-09-30.

Frazier Management Llc sold out a holding in . The sale prices were between $27.64 and $37.85, with an estimated average price of $34.42.