Oxford BioDynamics, Plc (AIM: OBD, the Company), a biotechnology company developing precision medicine tests for immune health based on the EpiSwitch® 3D genomics platform, announces the initial results from an interim analysis conducted for the REFINE-ALS prospective trial. The results from a subset of data, highlight the blood-based EpiSwitch prognostic stratification of patients with fast progressing Amyotrophic Lateral Sclerosis (ALS). The Phase 4 REFINE-ALS trial (NCT04259255)[1] is a prospective, multicenter study sponsored by Mitsubishi Tanabe Pharma America (MTPA) designed to identify biomarkers that could serve as quantifiable, biological and non-clinical measures of Edaravone’s pharmacodynamic effect in ALS. To date, in the U.S., RADICAVA and RADICAVA ORS have been used to treat over 8,000 patients, with over 1.1 million days of therapy, and have been prescribed by nearly 2,000 HCPs[2].
Massachusetts General Hospital Reports Results of Interim Analysis from REFINE-ALS Biomarker Trial by Mitsubishi Tanabe Pharma USA, Utilizing Oxford Biodynamics' EpiSwitch® Platform for Prognostic Stratification of Fast Progression ALS
Dec 16, 2022
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