Sonnet BioTherapeutics Announces Pharmacokinetic and Pharmacodynamic Data in a Phase 1 Dose-Escalation Trial of SON-1010

Jan 19, 2023

24 healthy volunteers have been dosed in study SB102 to assess the safety, PK, and PD of SON-1010 without the background of prior chemotherapy
PK data shows an extended half-life of SON-1010 of approximately 112 hours, compared to 12 hours for rhIL-12
Simulation of the controlled and prolonged induction of IFNg and minimal related adverse events suggest that dose escalation can continue

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