MacroGenics Announces Preliminary Clinical Results from Single Arm Study of Lorigerlimab in Patients with Metastatic Castration-Resistant Prostate Cancer to be Presented at ASCO Genitourinary Cancers Symposium

Feb 13, 2023

Twelve of 42 patients (28.6%) in metastatic castration-resistant prostate cancer (mCRPC) cohort achieved ≥ 50% prostate-specific antigen (PSA) reduction (PSA50), including 9 (21.4%) who achieved ≥ 90% PSA reduction (PSA90)
Nine of 35 patients (25.7%) with measurable mCRPC achieved confirmed partial responses
Manageable overall safety profile observed across multiple expansion cohorts
Company plans to initiate Phase 2 study in mCRPC in 2023

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