What's Driving Twist Bioscience Corp's Surprising 14% Stock Rally?

Twist Bioscience Corp (TWST, Financial) has recently caught the attention of investors with its notable stock performance. The company's market capitalization stands at $1.47 billion, with the current stock price at $25.51. Over the past week, TWST has seen a gain of 1.81%, and over the past three months, the stock has surged by 14.18%. This growth is particularly intriguing when compared to the company's GF Value of $59.31, which suggests a possible value trap, indicating that investors should think twice before investing. This is a significant shift from the past GF Value of $111.54, which labeled the stock as significantly undervalued. Such a change in valuation requires a closer look at the company's fundamentals and market position.

Understanding Twist Bioscience Corp

Twist Bioscience Corp operates within the Medical Diagnostics & Research industry, focusing on the development of a synthetic DNA synthesis platform. This innovative technology allows for the rapid and cost-effective production of high-quality synthetic DNA, which has a wide range of applications in various fields, including medicine and biotechnology. The company's unique approach, which synthesizes DNA on silicon rather than traditional plastic plates, positions it at the forefront of the synthetic biology industry. The majority of Twist Bioscience's revenue is generated in the United States, reflecting its strong presence in the domestic market. 1729882826439979008.png

Profitability Concerns

Despite its innovative platform, Twist Bioscience's Profitability Rank is low at 2 out of 10. The company's operating margin is deeply negative at -84.41%, although it fares better than 26.2% of 229 companies in the industry. Its Return on Equity (ROE) and Return on Assets (ROA) are also in the negative territory, at -29.06% and -23.73% respectively. The Return on Invested Capital (ROIC) stands at a concerning -48.71%. These figures suggest that Twist Bioscience is struggling to translate its innovative technology into financial profitability when compared to its industry peers.

Growth Trajectory

On the brighter side, Twist Bioscience's Growth Rank is strong at 7 out of 10. The company has demonstrated impressive revenue growth, with a 24.00% 3-Year Revenue Growth Rate per Share and an even more robust 43.90% 5-Year Revenue Growth Rate per Share. However, its earnings per share (EPS) growth rates are negative over the same periods, at -3.70% and -5.60% respectively. These mixed growth indicators suggest that while the company is expanding its top-line revenue, it has yet to achieve profitability and consistent earnings growth.

Investor Holdings

Notable investors have taken significant positions in Twist Bioscience. Catherine Wood (Trades, Portfolio) holds 6,785,983 shares, representing 11.82% of the company, while Baillie Gifford (Trades, Portfolio) owns 1,268,295 shares, accounting for 2.21%. Joel Greenblatt (Trades, Portfolio) has a smaller stake with 42,598 shares, which is 0.07% of the company. The confidence of these major holders could be a signal of the company's potential, despite the current financial metrics.

Competitive Landscape

When compared to its competitors, Twist Bioscience stands in the middle of the pack in terms of market capitalization. OPKO Health Inc (OPK, Financial) has a market cap of $1.24 billion, while Fulgent Genetics Inc (FLGT, Financial) is valued at $832.564 million. Myriad Genetics Inc (MYGN, Financial) leads with a market cap of $1.75 billion. This comparison highlights the competitive nature of the Medical Diagnostics & Research industry and the need for Twist Bioscience to continue innovating and improving its financial health to maintain and grow its market position.


In conclusion, Twist Bioscience Corp's recent stock price rally is a reflection of its growth potential and innovative technology. However, the company's profitability metrics and negative EPS growth rates raise concerns about its current financial stability. The positions held by major investors suggest a belief in the company's future, but the competitive landscape indicates that Twist Bioscience must work diligently to capitalize on its technological advantages. Investors should carefully consider the company's growth prospects against the backdrop of its financial health and industry competition before making investment decisions.

This article, generated by GuruFocus, is designed to provide general insights and is not tailored financial advice. Our commentary is rooted in historical data and analyst projections, utilizing an impartial methodology, and is not intended to serve as specific investment guidance. It does not formulate a recommendation to purchase or divest any stock and does not consider individual investment objectives or financial circumstances. Our objective is to deliver long-term, fundamental data-driven analysis. Be aware that our analysis might not incorporate the most recent, price-sensitive company announcements or qualitative information. GuruFocus holds no position in the stocks mentioned herein.


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