Novartis Kymriah® demonstrates consistent efficacy and safety outcomes in US patients when used in real-world setting

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Dec 09, 2019
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- Efficacy in DLBCL confirmed results seen in the pivotal trial despite treatment of a broader population, including older and more heavily pretreated patients1-3

- Fewer known CAR-T cell therapy adverse events for patients with DLBCL, specifically rates of high-grade cytokine release syndrome (4%) and neurologic events (5%), were observed compared with the pivotal clinical trials1-3

- In children and young adults with ALL, efficacy outcomes were similar and safety outcomes appear to be more favorable compared to the pivotal trial4

- Understanding the Kymriah safety profile, and increased experience with administration in real-world practice supports use in the outpatient setting

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