Takara Bio (FRA:TF2) 3-Year ROIIC % : -50.18% (As of Mar. 2026)


FRA:TF2 Takara Bio Inc FRA:TF2
50 GF Score
Price €5.95
GF Value €4.47
! 6 Warning Signs
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What is Takara Bio 3-Year ROIIC %?

Takara Bio FRA:TF2 50 3-Year ROIIC % is -50.18 as of Mar. 2026. GuruFocus rates FRA:TF2 with a GF Score™ of 50/100 and a GF Value™ of €4.47. The stock has 6 warning signs investors should review. Among 1,322 Biotechnology companies, Takara Bio ranks worse than 65.28% on this metric.

3-Year Return on Invested Incremental Capital (3-Year ROIIC %) measures the change in earnings as a percentage of change in investment over 3-year. Takara Bio's 3-Year ROIIC % for the quarter that ended in Mar. 2026 was -50.18%. High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

The industry rank for Takara Bio's 3-Year ROIIC % or its related term are showing as below:

FRA:TF2's 3-Year ROIIC % is ranked worse than
65.28% of 1322 companies
in the Biotechnology industry
Industry Median: -4.82 vs FRA:TF2: -50.18

Takara Bio  (FRA:TF2) 3-Year ROIIC % Explanation

Return on Incremental Invested Capital (ROIIC) is an extension of Return on Investment Capital (ROIC). ROIC % tells investors how efficiently that profitability is earned per dollar of company capital. ROIIC narrows the focus even further and shows how profitable each additional unit of capital investment could be. ROIIC % is a more powerful metric than ROIC because it measures how much money the company can generate going forward on future capital investments.

High ROIIC is generally an indication that your business is capital efficient or has a higher operating leverage.

Be Aware

It's important to keep in mind that when tracking ROIIC, the metric is better suited to forecasting the trend of future returns rather than measuring current return on investment.


Takara Bio 3-Year ROIIC % Related Terms


Takara Bio 3-Year ROIIC % Historical Data

* Premium members only.

The historical data trend for Takara Bio's 3-Year ROIIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Takara Bio 3-Year ROIIC % Chart

Takara Bio Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
3-Year ROIIC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 52.07 57.71 -31.09 -164.30 -50.18

Takara Bio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year ROIIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -164.30 0.00 0.00 0.00 -50.18

FRA:TF2 vs VRTX, REGN, ALNY: 3-Year ROIIC % Comparison

For the Biotechnology subindustry, Takara Bio's 3-Year ROIIC %, along with its competitors' market caps and 3-Year ROIIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Takara Bio 3-Year ROIIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Takara Bio's 3-Year ROIIC % distribution charts can be found below:

* The bar in red indicates where Takara Bio's 3-Year ROIIC % falls into.


FRA:TF2
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Takara Bio Inc FRA:TF2
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Takara Bio 3-Year ROIIC % Calculation

Takara Bio's 3-Year ROIIC % for the quarter that ended in Mar. 2026 is calculated as:

3-Year ROIIC %=3-Year Incremental Net Operating Profit After Taxes (NOPAT)**/3-Year Incremental Invested Capital**
=( -25.544 (Mar. 2026) - 108.5517648 (Mar. 2023) )/( 601.014 (Mar. 2026) - 488.821 (Mar. 2023) )
=-134.0957648/112.193
=-119.52%***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** Annual data of NOPAT and Invested Capital was used to calculate 3-Year ROIIC %.
*** Please be aware that the ROIIC (Return on Invested Capital) calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

Frequently Asked Questions Learn more about 3-Year ROIIC % →
What does a 3-Year ROIIC % of -50.18 mean?
Takara Bio (FRA:TF2) has a 3-Year ROIIC % of -50.18 as of Mar. 2026. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Takara Bio and its competitors. According to the industry distribution chart, Takara Bio ranks #863 out of 1322 companies in the Biotechnology industry, placing it in the top 65.3%.
Is Takara Bio's 3-Year ROIIC % too high?
Takara Bio's current 3-Year ROIIC % is -50.18. Based on the distribution chart, Takara Bio ranks #863 out of 1322 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Takara Bio has a GF Score™ of 50/100, reflecting its overall financial health beyond just this single metric.
How does Takara Bio's 3-Year ROIIC % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Takara Bio ranks #863 out of 1322 companies for 3-Year ROIIC %. This places Takara Bio in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year ROIIC % for a Biotechnology company?
A good 3-Year ROIIC % depends on the Biotechnology industry context. However, 3-Year ROIIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year ROIIC % mean?
A high 3-Year ROIIC % can signal that a stock is expensive relative to its fundamentals. 3-Year ROIIC % measures the change in earnings as a percentage of change in investment over 3-year. View historical data on Takara Bio and its competitors. Takara Bio's current 3-Year ROIIC % is -50.18. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Takara Bio stock overvalued right now?
Takara Bio (FRA:TF2) has a current 3-Year ROIIC % of -50.18. The stock's GF Value™ is €4.47, compared to a current price of €5.95 — trading 33.1% above its estimated fair value. The current 3-Year ROIIC % is -50.18. Takara Bio's overall GF Score™ is 50/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year ROIIC % calculated?
3-Year ROIIC % is calculated from a company's financial statements. For Takara Bio (FRA:TF2), the current 3-Year ROIIC % is -50.18 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Takara Bio (FRA:TF2) Overvalued in 2026?

Based on GuruFocus' analysis, Takara Bio stock appears to be overvalued. The current stock price of €5.95 is trading 33.1% above its estimated GF Value™ of €4.47.

Key valuation signals for FRA:TF2:

  • 3-Year ROIIC %: -50.18
  • GF Value™: €4.47 vs. price of €5.95 (33.1% above fair value)
  • GF Score™: 50/100 with 6 warning signs

No single metric tells the full story. See the FRA:TF2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Takara Bio Business Description

Other Exchanges 4974:Japan
Address Nojihigashi 7-4-38 Kusatu, Shiga, Otsu, JPN, 520-0058
Takara Bio Inc is a biotechnology company that develops gene therapy procedures. The company reports in three business segments: Bioindustry, Gene therapy, and AgriBio. Takara's bioindustry business provides research reagents, scientific instruments, and various contracted services to universities and companies around the world. The company's gene therapy business is focused on treating cancer and HIV. Its AgriBio business aims to leverage biotechnologies in the food ingredient field, including large-scale mushroom production. The vast majority of Takara's revenue is derived from its bioindustry segment.
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3-Year ROIIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€5.95
Price
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