ARCA:XBI

State Street SPDR S&P Biotech ETF

$ 163.81 -0.57 ( -0.35%) 04:00 PM EST
PE Ratio:
16.81
PB Ratio:
4.53
Volume:
3.72M
Dividend Yield %:
0.35
Last Holding update 2026-08-28 152 Stocks (23 new)
Value $10.72 Bil Turnover 23 %
Top Holdings: APGE(1.49%) MRNA(1.41%) TWST(1.41%) ORKA(1.38%) KYMR(1.36%)
Registrant: State Street(R) SPDR(R) S&P(R) Biotech ETF
Year: 2026
To
10Y: -%
Above Low: +NaN%
Below High: NaN%
Performance Chart Fundamental Charts Technical Indicators Gurus Trades Top Holdings Sector Breakdowns Holding History Back to Top

GuruFocus Rankings

Financial Strength
6 /10
Profitability Rank
3 /10
GF Value Rank
3 /10
Growth Rank
7 /10
Momentum Rank
6 /10

State Street SPDR S&P Biotech ETF Geographic Breakdown

State Street SPDR S&P Biotech ETF Performance

Dividend
Log
Bar
To

Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

State Street SPDR S&P Biotech ETF Key Statistics

Name Value
Day's Open ($) 162.74
Day's Range ($) 162.51 - 164.35
Day's Volume 3,719,592
52-Week Range ($) 92.49 - 169.89
Beta 1.1245
3-Year Sharpe Ratio 0.89
3-Year Sortino Ratio 1.63
Volatility 23.09
14-Day RSI 55.14
14-Day ATR ($) 4.057926
20-Day SMA ($) 162.9895

Fundamental Data

Name Value
Market Cap (Mil $) 11,614.129
Shares Outstanding (Mil) 70.9
PE Ratio 16.81
PE Ratio (10y Range) -
PE Ratio (10y Median) -
PB Ratio 4.53
PB Ratio (10y Range) -
PB Ratio (10y Median) -

Dividend Data

Name Value
Dividends per Share (TTM) ($) -
Dividend Yield % 0.35
Dividend Yield % (10y Range) -
Dividend Yield % (10y Median) -
Next Dividend Payment Date
Dividend Frequency Quarterly

XBI State Street SPDR S&P Biotech ETF Fundamental Charts

Historical TTM Price-to-Earnings for XBI State Street SPDR S&P Biotech ETF

Historical TTM Price-to-Earnings without NRI for XBI State Street SPDR S&P Biotech ETF

Historical Price-to-Book Ratio for XBI State Street SPDR S&P Biotech ETF

Historical Dividend Yields for XBI State Street SPDR S&P Biotech ETF

State Street SPDR S&P Biotech ETF Technical Indicators

Moving Average

Momentum

Gurus Latest Trades with ARCA:XBI

No Available Data

ARCA:XBI is held by these investors

No Available Data
State Street(R) SPDR(R) S&P(R)... Top Holdings of 2026-06-30 View Full List
Ticker
Company
Shares
Value ($1000)
Shares Change %
Weighting %
Trade Impact %
% of Shares outstanding
3M Change %
YTD Change %
Market Cap $Mil
Industry
APGE
Apogee Therapeutics Inc
1,203,674
159,763.6
+49.42%
1.490
+0.49%
1.590
+60.43%
+78.95%
10,223.1
Biotechnology
MRNA
Moderna Inc
2,164,892
151,607.4
-35.15%
1.410
-0.44%
0.540
+182.13%
+393.56%
58,108.8
Biotechnology
TWST
Twist Bioscience Corp
1,469,111
151,142.1
-22.40%
1.410
-0.17%
2.340
+68.70%
+293.19%
8,210.6
Biotechnology
ORKA
Oruka Therapeutics Inc
1,555,002
147,989.5
+143.86%
1.380
+0.81%
2.350
+48.64%
+205.41%
6,129.0
Biotechnology
KYMR
Kymera Therapeutics Inc
1,272,754
145,946.7
+30.26%
1.360
+0.32%
1.530
+57.46%
+50.98%
9,768.5
Biotechnology
VKTX
Viking Therapeutics Inc
3,587,998
139,967.8
+38.96%
1.310
+0.37%
3.080
+17.09%
-0.88%
4,067.7
Biotechnology
PRAX
Praxis Precision Medicines Inc
413,737
138,515.0
+11.70%
1.290
+0.14%
1.480
+32.79%
+19.28%
9,815.6
Biotechnology
ERAS
Erasca Inc
7,447,165
136,432.1
+243.04%
1.270
+0.90%
2.130
+22.08%
+335.48%
5,666.1
Biotechnology
RVMD
Revolution Medicines Inc
690,499
129,316.6
-44.51%
1.210
-0.57%
0.320
+34.90%
+163.68%
45,014.9
Biotechnology
RYTM
Rhythm Pharmaceuticals Inc
1,161,672
128,980.4
+25.59%
1.200
+0.24%
1.690
+17.27%
-4.02%
7,073.9
Biotechnology

State Street(R) SPDR(R) S&P(R) Biotech ETF's Historical Top Holdings Breakdowns

State Street(R) SPDR(R) S&P(R) Biotech ETF's Top Stock Picks View Full List
Ticker
Company
Date
Action
Impact %
Price Range
Price
Price Change from Avrg%
Comment
Current Shares
Share Change
FOLD Unlock Delisted
Amicus Therapeutics Inc
2026-06-30
Sold Out
Sold Out
-1.49%
●
14.44 ($14.46) 14.49
$14.49
0.21%
Sold Out
0
-8,213,589
SLS
SELLAS Life Sciences Group Inc
2026-06-30
New Buy
New Buy
+1.19%
●
4.13 ($6.86) 15.45
$13.86
102.04%
New holding
8,654,720
8,654,720
ACLX Unlock Delisted
Arcellx Inc
2026-06-30
Sold Out
Sold Out
-0.96%
●
114.72 ($114.93) 115.1
$115.07
0.12%
Sold Out
0
-1,158,034
SLNO Unlock Delisted
Soleno Therapeutics Inc
2026-06-30
Sold Out
Sold Out
-0.94%
●
33.48 ($51.34) 53.01
$53.01
3.25%
Sold Out
0
-1,592,549
APLS Unlock Delisted
Apellis Pharmaceuticals Inc
2026-06-30
Sold Out
Sold Out
-0.92%
●
40.23 ($40.86) 41.12
$41.03
0.42%
Sold Out
0
-2,856,301
ERAS
Erasca Inc
2026-06-30
Add
Add
+0.90%
●
9.11 ($14.33) 22.47
$16.20
13.05%
Add 243.04%
7,447,165
5,276,221
ORKA
Oruka Therapeutics Inc
2026-06-30
Add
Add
+0.81%
●
49.05 ($66.35) 95.17
$92.57
39.52%
Add 143.86%
1,555,002
917,346
INSM
Insmed Inc
2026-06-30
Add
Add
+0.57%
●
91.88 ($121.76) 164.86
$126.29
3.72%
Add 112.31%
1,083,724
573,276
RVMD
Revolution Medicines Inc
2026-06-30
Reduce
Reduce
-0.57%
●
95.36 ($145.29) 192.62
$210.02
44.55%
Reduce -44.51%
690,499
-553,883
RLAY
Relay Therapeutics Inc
2026-06-30
Add
Add
+0.54%
●
9.95 ($14.44) 19.74
$19.04
31.86%
Add 96.38%
6,304,701
3,094,268

State Street(R) SPDR(R) S&P(R) Biotech ETF Total Holding History ($B)

To

State Street(R) SPDR(R) S&P(R) Biotech ETF's Asset Allocation

To

State Street(R) SPDR(R) S&P(R) Biotech ETF Past Portfolios

Portfolio Date Number of Stocks New Stocks Total Value ($Mil) Q/Q Turnover

Top Ranked Articles

  • 1

State Street(R) SPDR(R) S&P(R) Biotech ETF's Hypothetical Growth since 2026-06-30

State Street(R) SPDR(R) S&P(R) Biotech ETF's Yearly Returns

This information is only displayed for Gurus who publicly disclose audited performance records; most hedge funds and private investment firms do not publish such data or only provide limited historical performance information.

Year Portfolio % % Excess Gain %

State Street(R) SPDR(R) S&P(R) Biotech ETF's Holdings Heat Map

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State Street(R) SPDR(R) S&P(R) Biotech ETF's Holdings Bubble Chart

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