International Biotechnology Trust Plc Buys Biogen Inc, Amgen Inc, Insmed Inc, Sells Celgene Corp, Aerie Pharmaceuticals Inc, Alkermes PLC

• New Purchases: ARQL, IOVA, QURE, RGEN, BPMC, EXAS, CNCE, PRQR,
• Added Positions: AMGN, BIIB, INSM, VRTX, NBIX, EXEL, ALXN, GILD, IONS, SRPT, GTHX, ASND, MLND, SGMO, BHVN, PTCT, MNTA, MYGN, TCDA,
• Reduced Positions: CELG, ALKS, ACAD, ZGNX, RTRX, REGN, SUPN, INCY, RDUS, AKCA, GWPH, MRTX, KALV, STML,
• Sold Out: AERI, ENTA, WVE, ARRY, IFRX, MGNX,

For the details of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's stock buys and sells, go to https://www.gurufocus.com/guru/international+biotechnology+trust+plc/current-portfolio/portfolio

1. Gilead Sciences Inc (GILD) - 316,284 shares, 7.97% of the total portfolio. Shares added by 13.66%
2. Vertex Pharmaceuticals Inc (VRTX) - 85,022 shares, 5.81% of the total portfolio. Shares added by 66.31%
3. Neurocrine Biosciences Inc (NBIX) - 156,800 shares, 4.94% of the total portfolio. Shares added by 51.35%
4. Celgene Corp (CELG) - 142,522 shares, 4.91% of the total portfolio. Shares reduced by 39.49%
5. Alexion Pharmaceuticals Inc (ALXN) - 98,641 shares, 4.82% of the total portfolio. Shares added by 33.95%

International Biotechnology Trust Plc initiated holding in Arqule Inc. The purchase prices were between $4.77 and $11.01, with an estimated average price of $6.96. The stock is now traded at around $8.64. The impact to a portfolio due to this purchase was 0.98%. The holding were 239,103 shares as of .

International Biotechnology Trust Plc initiated holding in Iovance Biotherapeutics Inc. The purchase prices were between $9.78 and $24.52, with an estimated average price of $15.03. The stock is now traded at around $20.02. The impact to a portfolio due to this purchase was 0.95%. The holding were 104,000 shares as of .

International Biotechnology Trust Plc initiated holding in uniQure NV. The purchase prices were between $52.76 and $82.19, with an estimated average price of $63.55. The stock is now traded at around $56.02. The impact to a portfolio due to this purchase was 0.8%. The holding were 27,500 shares as of .

International Biotechnology Trust Plc initiated holding in Repligen Corp. The purchase prices were between $54.2 and $85.95, with an estimated average price of $67.97. The stock is now traded at around $88.40. The impact to a portfolio due to this purchase was 0.77%. The holding were 24,000 shares as of .

International Biotechnology Trust Plc initiated holding in Blueprint Medicines Corp. The purchase prices were between $73.54 and $97.8, with an estimated average price of $82.43. The stock is now traded at around $81.73. The impact to a portfolio due to this purchase was 0.6%. The holding were 17,000 shares as of .

International Biotechnology Trust Plc initiated holding in Exact Sciences Corp. The purchase prices were between $89.51 and $118.04, with an estimated average price of $100.57. The stock is now traded at around $118.22. The impact to a portfolio due to this purchase was 0.47%. The holding were 10,700 shares as of .

International Biotechnology Trust Plc added to a holding in Amgen Inc by 175.00%. The purchase prices were between $166.7 and $195.41, with an estimated average price of $178.91. The stock is now traded at around $199.31. The impact to a portfolio due to this purchase was 2.89%. The holding were 66,000 shares as of .

International Biotechnology Trust Plc added to a holding in Biogen Inc by 349.47%. The purchase prices were between $219.29 and $241.72, with an estimated average price of $230.78. The stock is now traded at around $227.63. The impact to a portfolio due to this purchase was 2.89%. The holding were 42,700 shares as of .

International Biotechnology Trust Plc added to a holding in Insmed Inc by 224.18%. The purchase prices were between $23 and $32.19, with an estimated average price of $27.86. The stock is now traded at around $15.49. The impact to a portfolio due to this purchase was 2.35%. The holding were 356,600 shares as of .

International Biotechnology Trust Plc added to a holding in Vertex Pharmaceuticals Inc by 66.31%. The purchase prices were between $164.61 and $190.37, with an estimated average price of $174.67. The stock is now traded at around $181.12. The impact to a portfolio due to this purchase was 2.32%. The holding were 85,022 shares as of .

International Biotechnology Trust Plc added to a holding in Neurocrine Biosciences Inc by 51.35%. The purchase prices were between $72.24 and $91.27, with an estimated average price of $82.02. The stock is now traded at around $94.88. The impact to a portfolio due to this purchase was 1.68%. The holding were 156,800 shares as of .

International Biotechnology Trust Plc added to a holding in Exelixis Inc by 82.12%. The purchase prices were between $18.93 and $24.75, with an estimated average price of $20.95. The stock is now traded at around $19.94. The impact to a portfolio due to this purchase was 1.6%. The holding were 443,534 shares as of .

International Biotechnology Trust Plc sold out a holding in Aerie Pharmaceuticals Inc. The sale prices were between $28.97 and $48.21, with an estimated average price of $38.56.

International Biotechnology Trust Plc sold out a holding in Enanta Pharmaceuticals Inc. The sale prices were between $81.3 and $97.35, with an estimated average price of $89.96.

International Biotechnology Trust Plc sold out a holding in WAVE Life Sciences Ltd. The sale prices were between $22.93 and $42.84, with an estimated average price of $27.96.

International Biotechnology Trust Plc sold out a holding in Array BioPharma Inc. The sale prices were between $20.84 and $46.58, with an estimated average price of $27.97.

International Biotechnology Trust Plc sold out a holding in InflaRx NV. The sale prices were between $3.06 and $51.61, with an estimated average price of $31.98.

International Biotechnology Trust Plc sold out a holding in Macrogenics Inc. The sale prices were between $14.51 and $19.71, with an estimated average price of $17.19.