Geron Corp (LTS:0IV3)
$ 1.25 -0.15 (-10.71%) Market Cap: 827.56 Mil Enterprise Value: 637.23 Mil PE Ratio: 0 PB Ratio: 3.61 GF Score: 46/100

Q3 2025 Geron Corp Earnings Call Transcript

Nov 05, 2025 / 01:00PM GMT
Release Date Price: $1.11 (-5.93%)

Key Points

Positve
  • Geron Corp (GERN) reported a net product revenue of $47.2 million for the third quarter, showing growth compared to the previous year.
  • The company has a strong cash position of approximately $420 million, which is deemed sufficient to support its commercial and medical affairs initiatives.
  • Geron Corp (GERN) has expanded its prescribing accounts by 15% in the quarter, adding approximately 150 new ordering accounts.
  • The company completed its first shipment of RYTELO to Germany under a name patient early access program, preparing for commercialization in select EU markets in 2026.
  • Geron Corp (GERN) has a robust pipeline with ongoing clinical trials, including the fully enrolled phase 3 trial in relapsed refractory myelofibrosis, with interim analysis expected in the second half of 2026.
Negative
  • Demand for RYTELO was down 3% compared to the last quarter, with new patient starts not offsetting discontinuations.
  • The company faces challenges in establishing RYTELO as a second-line therapy and educating healthcare providers on its use.
  • Geron Corp (GERN) reported increased operating expenses, with selling, general, and administrative expenses rising to $39 million from $36 million in the previous year.
  • The company is experiencing high inventory levels at distributors, which could impact future sales.
  • There is a need for increased awareness and education among healthcare providers to drive the adoption of RYTELO, which may take time to achieve.
Operator

Hello and welcome to the Geron Corporation third-quarter 2025 earnings call. (Operator Instructions) I would now like to turn the call over to Dawn Schottlandt, Senior Vice President, Investor Relations and Corporate Affairs. You may begin.

Dawn Schottlandt
Geron Corp - Senior Vice President-Investor Relations and Corporate Affairs

Good morning, everyone. Welcome to the Geron Corporation third-quarter 2025 earnings conference call.

Before we begin, please note that during the course of this presentation and question-and-answer session, we will be making forward-looking statements regarding future events, performance, plans, expectations, and other projections, including those relating to the launch, commercial opportunity, and therapeutic potential of RYTELO; anticipated clinical and commercial events and related timelines; the sufficiency of Geron's financial resources; and other statements that are not historical facts. Actual events or results could differ materially.

Therefore, I refer you to the discussion under the heading, Risk

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