Q4 2025 Pfizer Inc Earnings Call Transcript

Feb 03, 2026 / 03:00PM GMT

Release Date Price: MXN446.95 (-3.00%)

Transcript 8-K

Key Points

Positve

Pfizer Inc (PFE) exceeded expectations for revenues and adjusted diluted EPS for the full year 2025.
The company returned $9.8 billion to shareholders via quarterly dividends.
Pfizer Inc (PFE) achieved solid double-digit growth in recently launched and acquired products.
The company expanded its adjusted gross margins and resolved significant uncertainties related to pricing and tariffs.
Pfizer Inc (PFE) made strategic acquisitions, including Seagen, Metsera, and Biohaven, which have transformative potential for the company.

Negative

Pfizer Inc (PFE) experienced a 2% operational decline in full-year 2025 revenues compared to the previous year.
The company's COVID-19 product revenues declined approximately 40% operationally year-over-year in the fourth quarter of 2025.
Pfizer Inc (PFE) recorded a loss per share of $0.29 on a GAAP basis for the fourth quarter.
The company faced $4.4 billion in non-cash intangible asset impairments related to several medicines in development and in-line products.
Pfizer Inc (PFE) anticipates revenue compression of approximately $1.5 billion in 2026 due to products impacted by anticipated generic entry.

Operator

Good day, everyone, and welcome to Pfizer's fourth-quarter 2025 earnings conference call. Today's call is being recorded. At this time, I would like to turn the call over to Francesca DeMartino, Chief Investor Relations Officer and Senior Vice President. Please go ahead, ma'am.

Francesca DeMartino

Pfizer Inc - Chief Investor Relations Officer and Senior Vice President

Good morning, and welcome to Pfizer's earnings call. I'm Francesca DeMartino, Chief Investor Relations Officer. On behalf of the Pfizer team, thank you for joining us. This call is being made available via audio webcast at pfizer.com. Earlier this morning, we released our results for the fourth quarter and full year 2025 via a press release that is available on our website at pfizer.com.

I'm joined today by Dr. Albert Bourla, our Chairman and CEO; and Dr. Chris Boshoff, our Scientific Officer -- Chief Scientific Officer; and Dave Denton, our CFO. Albert, Chris and Dave have some prepared remarks, and we will then open the call for questions.

Members of our leadership team will

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