Q1 2025 Sarepta Therapeutics Inc Earnings Call Transcript
Key Points
- Sarepta Therapeutics Inc (SRPT) achieved $612 million in total net product revenue for Q1 2025, representing a 70% growth over the same quarter last year.
- ELEVIDYS sales reached $375 million in Q1, marking a 180% increase over the same quarter last year.
- The company maintains a strong cash position with $647 million in cash, cash equivalents, and investments, plus an additional $600 million available through a revolving credit facility.
- Sarepta Therapeutics Inc (SRPT) has four approved therapies generating significant revenue and growth potential.
- The company is actively working to expand its site capacity and improve administrative processes to enhance patient access to ELEVIDYS.
- Sarepta Therapeutics Inc (SRPT) revised its net product revenue guidance for 2025 to $2.3 billion to $2.6 billion, down from previous expectations.
- A tragic safety event involving a patient death due to acute liver failure has impacted the company's reputation and caused delays in patient infusions.
- The administrative process for gene therapy infusions is complex, leading to delays and impacting revenue timing.
- There is an imbalance in site capacity, with top sites being fully booked, which limits immediate patient access.
- The company faces challenges in educating the broader physician and patient community about the safety and efficacy of ELEVIDYS, impacting uptake.
Good afternoon, and welcome to the Sarepta Therapeutics first-quarter 2025 financial results conference call. As a reminder, today's program is being recorded.
At this time, I'll turn the call over to Mary Jenkins, Associate Director, Investor Relations. Please go ahead.
Thank you, Martin, and thank you all for joining today's call. Earlier this afternoon, we released our financial results for the first quarter of 2025. The press release, slides and supplementary information are available on the Investor section of our website at sarepta.com, and our 10-Q was filed with the SEC this afternoon. Joining us on the call today are Doug Ingram, Ian Stepan, Dylan Murray and Dr. Louise Rodino-Klapac. After our formal remarks, we'll open the call for Q&A. I'd like to note that during this call, we will be making a number of forward-looking statements. Please refer to Slide 2 on the webcast, which contains our forward-looking statements. These forward-looking statements involve
Access to All Earning Calls and Stock Analysis | |
30-Year Financial on one screen | |
All-in-one Stock Screener with unlimited filters | |
Customizable Stock Dashboard | |
Real Time Insider Trading Transactions | |
8,000+ Institutional investors’ 13F holdings | |
Powerful Excel Add-in and Google sheets Add-on | |
All data downloadable | |
Quick customer support | |
And much more... |


