Q4 2025 Pacific Biosciences of California Inc Earnings Call Transcript

Feb 12, 2026 / 10:00 PM GMT

Release Date Price: €1.54 (+0.48%)

Transcript 10-K8-K

Key Points

Positve

Pacific Biosciences of California Inc (PACB) reported a 14% year-over-year revenue growth in Q4 2025, reaching $44.6 million.
Consumable revenue reached record levels, with a 15% year-over-year increase, driven by strong demand in clinical sequencing applications.
The company achieved a significant improvement in non-GAAP gross margin, increasing from 31% in Q4 2024 to 40% in Q4 2025.
The launch of the SparkNex chemistry is expected to lower the price per genome, potentially increasing system utilization and expanding market share.
PACB successfully reduced non-GAAP operating expenses by 18% year-over-year, contributing to a lower cash burn and improved financial profile.

Negative

Instrument revenue decreased by 18% for the full year 2025, primarily due to lower Revio shipments.
The academic funding environment remains challenging, impacting instrument sales and creating uncertainty for future growth.
Despite strong growth in consumables, the overall revenue growth for 2025 was only 4%, indicating potential headwinds in other areas.
The company anticipates continued volatility in component costs, such as memory, which could impact gross margins.
PACB's cash and investments decreased from $389.9 million at the end of 2024 to $279.5 million at the end of 2025, reflecting ongoing financial pressures.

Refinitiv StreetEvents Event Transcript
E D I T E D V E R S I O N

PACB.OQ - Pacific Biosciences of California Inc
Q4 2025 Pacific Biosciences of California Inc Earnings Call
Feb 12, 2026 / 10:00PM GMT

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Presentation
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Unidentified_1 [1]
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