Q1 2025 Trevi Therapeutics Inc Earnings Call Transcript

May 8, 2025 / 08:30 PM GMT

Release Date Price: $6.6 (-0.90%)

Transcript 10-Q8-K

Key Points

Positve

Trevi Therapeutics Inc (TRVI) reported positive data from the Phase 2A river trial in RCC patients, achieving a statistically significant reduction in 24-hour objective cough frequency.
The company completed enrollment in the Phase 2b choral trial for IPF chronic cough patients, with data expected this quarter.
The RCC trial showed a 57% placebo-adjusted reduction in cough from baseline, indicating strong efficacy.
Trevi Therapeutics Inc (TRVI) has a cash runway into the fourth quarter of 2026, providing financial stability for ongoing trials.
The FDA provided clear guidance on a technical matter, indicating a positive regulatory relationship.

Negative

Trevi Therapeutics Inc (TRVI) reported a net loss of $10.4 million for the first quarter of 2025, slightly lower than the previous year.
R&D expenses decreased due to reduced costs related to a human abuse potential study, but personnel-related expenses increased.
G&A expenses increased to $3.7 million, primarily due to higher personnel-related costs.
The company faces challenges in the IPF study due to the complexity of the trial and the diverse patient population across 60 sites in 10 countries.
There is uncertainty regarding the long-term patient safety monitoring protocols for the phase 3 trial, which may require additional FDA feedback.

Refinitiv StreetEvents Event Transcript
E D I T E D V E R S I O N

TRVI.OQ - Trevi Therapeutics Inc
Q1 2025 Trevi Therapeutics Inc Earnings Call
May 08, 2025 / 08:30PM GMT

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Presentation
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Unidentified_1 [1]
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Good afternoon and welcome to the Trevvi Therapeutics first quarter 2025 earnings conference call. At this time, all participants will be in listen-only mode. Should you need assistance, please signal a conference specialist by pressing the star key followed by 0. After today's presentation, there'll be an opportunity to ask questions. To ask a question, you may press star, then 1 on your phone. To withdraw your question, please press 2. Please note this event is being recorded. Various remarks that management makes during this conference call about the company's future expectations, plans, and prospects constitute forward-looking statements for purposes of the safe harbor provisions under the Private Securities Litigation Reform

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