ARCA:XBI

State Street SPDR S&P Biotech ETF

$ 151.32 -4.9 ( -3.14%) 03:10 PM EST
PE Ratio:
16.96
PB Ratio:
4.48
Volume:
7.01M
Dividend Yield %:
0.37
Last Holding update 2026-02-27 148 Stocks (23 new)
Value $7.83 Bil Turnover 25 %
Top Holdings: FOLD(1.49%) PRAX(1.39%) TVTX(1.37%) BMRN(1.37%) HALO(1.33%)
Registrant: State Street(R) SPDR(R) S&P(R) Biotech ETF
Year: 2026
To
10Y: -%
Above Low: +NaN%
Below High: NaN%
Performance Chart Fundamental Charts Technical Indicators Gurus Trades Top Holdings Sector Breakdowns Holding History Back to Top

GuruFocus Rankings

Financial Strength
6 /10
Profitability Rank
3 /10
GF Value Rank
4 /10
Growth Rank
7 /10
Momentum Rank
6 /10

State Street SPDR S&P Biotech ETF Geographic Breakdown

State Street SPDR S&P Biotech ETF Performance

Dividend
Log
Bar
To

Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

State Street SPDR S&P Biotech ETF Key Statistics

Name Value
Day's Open ($) 155.02
Day's Range ($) 151.27 - 155.65
Day's Volume 7,014,105
52-Week Range ($) 84.39 - 165.71
Beta 1.1055
3-Year Sharpe Ratio 0.8
3-Year Sortino Ratio 1.46
Volatility 18.39
14-Day RSI 59.71
14-Day ATR ($) 4.185574
20-Day SMA ($) 153.828

Fundamental Data

Name Value
Market Cap (Mil $) 10,297.326
Shares Outstanding (Mil) 68.05
PE Ratio 16.96
PE Ratio (10y Range) 14.4 - 37.15
PE Ratio (10y Median) 18.3
PB Ratio 4.48
PB Ratio (10y Range) 2.75 - 6.16
PB Ratio (10y Median) 4.34

Dividend Data

Name Value
Dividends per Share (TTM) ($) 0.579
Dividend Yield % 0.37
Dividend Yield % (10y Range) 0.01 - 0.53
Dividend Yield % (10y Median) 0.23
Next Dividend Payment Date
Dividend Frequency Quarterly

XBI State Street SPDR S&P Biotech ETF Fundamental Charts

Historical TTM Price-to-Earnings for XBI State Street SPDR S&P Biotech ETF

Historical TTM Price-to-Earnings without NRI for XBI State Street SPDR S&P Biotech ETF

Historical Price-to-Book Ratio for XBI State Street SPDR S&P Biotech ETF

Historical Dividend Yields for XBI State Street SPDR S&P Biotech ETF

State Street SPDR S&P Biotech ETF Technical Indicators

Moving Average

Momentum

Gurus Latest Trades with ARCA:XBI

No Available Data

ARCA:XBI is held by these investors

No Available Data
State Street(R) SPDR(R) S&P(R)... Top Holdings of 2025-12-31 View Full List
Ticker
Company
Shares
Value ($1000)
Shares Change %
Weighting %
Trade Impact %
% of Shares outstanding
3M Change %
YTD Change %
Market Cap $Mil
Industry
FOLD
Amicus Therapeutics Inc
8,213,589
116,961.5
+67.90%
1.490
+0.60%
2.620
+1.54%
+1.76%
4,549.9
Biotechnology
PRAX
Praxis Precision Medicines Inc
370,413
109,175.5
-23.24%
1.390
-0.10%
1.340
-5.01%
+3.26%
8,484.6
Biotechnology
TVTX
Travere Therapeutics Inc
2,818,736
107,703.9
+141.72%
1.370
+0.80%
3.150
+39.30%
+44.15%
5,122.1
Biotechnology
BMRN
BioMarin Pharmaceutical Inc
1,804,534
107,243.5
-5.37%
1.370
-0.10%
0.940
+10.36%
+0.46%
11,540.0
Biotechnology
HALO
Halozyme Therapeutics Inc
1,546,804
104,099.9
+12.81%
1.330
+0.15%
1.310
+16.42%
+15.28%
9,202.6
Biotechnology
ROIV
Roivant Sciences Ltd
4,787,868
103,896.7
-20.84%
1.330
-0.33%
0.670
+15.79%
+55.76%
24,311.3
Biotechnology
EXEL
Exelixis Inc
2,359,522
103,417.9
-14.41%
1.320
-0.29%
0.910
+25.21%
+26.79%
13,967.8
Biotechnology
REGN
Regeneron Pharmaceuticals Inc
133,448
103,004.5
-28.64%
1.310
-0.53%
0.130
-9.26%
-12.20%
70,859.7
Biotechnology
PCVX
Vaxcyte Inc
2,228,160
102,807.3
+15.48%
1.310
+0.18%
1.550
-10.98%
+20.00%
7,995.3
Biotechnology
MDGL
Madrigal Pharmaceuticals Inc
175,411
102,148.8
-27.41%
1.300
-0.53%
0.770
+2.29%
-7.82%
12,375.6
Biotechnology

State Street(R) SPDR(R) S&P(R) Biotech ETF's Historical Top Holdings Breakdowns

State Street(R) SPDR(R) S&P(R) Biotech ETF's Top Stock Picks View Full List
Ticker
Company
Date
Action
Impact %
Price Range
Price
Price Change from Avrg%
Comment
Current Shares
Share Change
AKRO Unlock Delisted
Akero Therapeutics Inc
2025-12-31
Sold Out
Sold Out
-1.45%
●
46 ($53.31) 54.69
$54.65
2.51%
Sold Out
0
-1,741,151
MTSR Unlock Delisted
Metsera Inc
2025-12-31
Sold Out
Sold Out
-1.23%
●
51.7 ($59.45) 83.18
$70.50
18.59%
Sold Out
0
-1,336,340
CELC
Celcuity Inc
2025-12-31
Add
Add
+1.08%
●
46.07 ($82.79) 105.87
$88.32
6.68%
Add 819.88%
951,649
848,195
EXAS Unlock Delisted
Exact Sciences Corp
2025-12-31
Reduce
Reduce
-0.90%
●
56.19 ($80.68) 101.93
$104.91
30.03%
Reduce -49.57%
957,047
-940,563
RVMD
Revolution Medicines Inc
2025-12-31
Reduce
Reduce
-0.88%
●
45.7 ($65.88) 81.19
$177.95
170.11%
Reduce -46.41%
1,244,382
-1,077,627
MLYS
Mineralys Therapeutics Inc
2025-12-31
Add
Add
+0.80%
●
35.5 ($40.11) 47.33
$26.63
-33.62%
Add 423.65%
2,130,912
1,723,975
MIRM
Mirum Pharmaceuticals Inc
2025-12-31
Add
Add
+0.80%
●
64.1 ($71.76) 81.07
$117.83
64.19%
Add 183.94%
1,215,159
787,203
TVTX
Travere Therapeutics Inc
2025-12-31
Add
Add
+0.80%
●
24.22 ($32.64) 40.28
$55.08
68.75%
Add 141.72%
2,818,736
1,652,626
RNAM Unlock Delisted
Avidity Biosciences Inc
2025-12-31
Reduce
Reduce
-0.67%
●
44.18 ($64.94) 72.34
$71.34
9.86%
Reduce -39.37%
1,358,205
-881,776
ETNB Unlock Delisted
89bio Inc
2025-12-31
Sold Out
Sold Out
-0.63%
●
14.76 ($14.82) 14.87
$14.84
0.13%
Sold Out
0
-2,452,321

State Street(R) SPDR(R) S&P(R) Biotech ETF Total Holding History ($B)

To

State Street(R) SPDR(R) S&P(R) Biotech ETF's Asset Allocation

To

State Street(R) SPDR(R) S&P(R) Biotech ETF Past Portfolios

Portfolio Date Number of Stocks New Stocks Total Value ($Mil) Q/Q Turnover

Top Ranked Articles

  • 1

State Street(R) SPDR(R) S&P(R) Biotech ETF's Hypothetical Growth since 2025-12-31

State Street(R) SPDR(R) S&P(R) Biotech ETF's Yearly Returns

This information is only displayed for Gurus who publicly disclose audited performance records; most hedge funds and private investment firms do not publish such data or only provide limited historical performance information.

Year Portfolio % % Excess Gain %

State Street(R) SPDR(R) S&P(R) Biotech ETF's Holdings Heat Map

Size field:

State Street(R) SPDR(R) S&P(R) Biotech ETF's Holdings Bubble Chart

Discussions on State Street SPDR S&P Biotech ETF

User's Avatar
How would you rate this stock? XBI
No discussions yet.
Research Tools
All-In-One Screener Stock Ideas Stock List Guru List Guru Real-Time Picks Insider List Insider Trades Economic Indicators Sector & Industry Performance DCF Calculator Calculators Discussion Board
Product
Pricing Plans Excel Add-In Google Sheets Add-on Data API Stock Comparison Table Manual of Stocks Instant Alerts Mobile App Newsletters Signup 中文
Education
Financial Glossary Tutorials FAQ Buffett Indicator Shiller P/E Yield Curve Today U.S. Inflation Rate Global Market Valuation Fed Net Liquidity Buffett Assets Allocation
Company
About GuruFocus Career Contact Us Advertise Term of Use Privacy Policy Referral Program Partner Program
Survey

We'd love to learn more about your experiences on GuruFocus.com and how we can improve!

Take Survey
Follow Us
download GuruFocus on Apple store download GuruFocus on Google Play
Disclaimers
GuruFocus.com is not operated by a broker or a dealer. Under no circumstances does any information posted on GuruFocus.com represent a recommendation to buy or sell a security. The information on this site, and in its related newsletters, is not intended to be, nor does it constitute investment advice or recommendations. The individuals or entities selected as "gurus" may buy and sell securities before and after any particular article and report and information herein is published, with respect to the securities discussed in any article and report posted herein. Gurus may be added or dropped from the GuruFocus site at any time. In no event shall GuruFocus.com be liable to any member, guest or third party for any damages of any kind arising out of the use of any content or other material published or available on GuruFocus.com, or relating to the use of, or inability to use, GuruFocus.com or any content, including, without limitation, any investment losses, lost profits, lost opportunity, special, incidental, indirect, consequential or punitive damages. Past performance is a poor indicator of future performance. The information on this site, and in its related newsletters, is not intended to be, nor does it constitute investment advice or recommendations. The information on this site is in no way guaranteed for completeness, accuracy or in any other way. The gurus listed in this website are not affiliated with GuruFocus.com, LLC. Stock quotes are provided by QuoteMedia, Inc. (CSI). Company fundamental data is provided by Morningstar. Analyst estimates data is sourced from both Refinitiv and Morningstar, with priority given to Refinitiv data. Data is updated daily.
© 2004-2026 GuruFocus.com, LLC. All Rights Reserved.