Crescent Biopharma (FRA:C68) EV-to-FCF: -3.78 (As of Jul. 04, 2026)


FRA:C68 Crescent Biopharma Inc FRA:C68
10 GF Score
Price €14.60
! 2 Warning Signs
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What is Crescent Biopharma EV-to-FCF?

Crescent Biopharma FRA:C68 10 EV-to-FCF is -3.78 as of Jul. 04, 2026. GuruFocus rates FRA:C68 with a GF Score™ of 10/100. The stock has 2 warning signs investors should review. Among 332 Biotechnology companies, Crescent Biopharma ranks worse than 301204.52% on this metric.

EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, Crescent Biopharma's Enterprise Value is €252.58 Mil. Crescent Biopharma's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was €-66.78 Mil. Therefore, Crescent Biopharma's EV-to-FCF for today is -3.78.

The historical rank and industry rank for Crescent Biopharma's EV-to-FCF or its related term are showing as below:

FRA:C68' s EV-to-FCF Range Over the Past 10 Years
Min: -7.33   Med: -4.32   Max: -0.9
Current: -3.69

During the past 2 years, the highest EV-to-FCF of Crescent Biopharma was -0.90. The lowest was -7.33. And the median was -4.32.

FRA:C68's EV-to-FCF is ranked worse than
100% of 332 companies
in the Biotechnology industry
Industry Median: 16.26 vs FRA:C68: -3.69

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-07-04), Crescent Biopharma's stock price is €14.60. Crescent Biopharma's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was €-9.386. Therefore, Crescent Biopharma's PE Ratio (TTM) for today is At Loss.


Crescent Biopharma  (FRA:C68) EV-to-FCF Explanation

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Crescent Biopharma's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=14.60/-9.386
=At Loss

Crescent Biopharma's share price for today is €14.60.
Crescent Biopharma's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-9.386.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Crescent Biopharma EV-to-FCF Related Terms


Crescent Biopharma EV-to-FCF Historical Data

* Premium members only.

The historical data trend for Crescent Biopharma's EV-to-FCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Crescent Biopharma EV-to-FCF Chart

Crescent Biopharma Annual Data
Trend Dec24 Dec25
EV-to-FCF
0.00 -1.06

Crescent Biopharma Quarterly Data
Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-FCF Get a 7-Day Free Trial 0.00 0.00 0.00 -1.06 -4.15

FRA:C68 vs KYTX, ZURA, ARVN: EV-to-FCF Comparison

For the Biotechnology subindustry, Crescent Biopharma's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Crescent Biopharma EV-to-FCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Crescent Biopharma's EV-to-FCF distribution charts can be found below:

* The bar in red indicates where Crescent Biopharma's EV-to-FCF falls into.


FRA:C68
10GF Score
Crescent Biopharma Inc FRA:C68
EV-to-FCF is just one metric. See GF Score™, valuation, warning signs, and more.
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Crescent Biopharma EV-to-FCF Calculation

Crescent Biopharma's EV-to-FCF for today is calculated as:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=252.576/-66.778
=-3.78

Crescent Biopharma's current Enterprise Value is €252.58 Mil.
Crescent Biopharma's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-66.78 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-FCF →
What does a EV-to-FCF of -3.78 mean?
Crescent Biopharma (FRA:C68) has a EV-to-FCF of -3.78 as of Jul. 04, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Crescent Biopharma and its competitors. According to the industry distribution chart, Crescent Biopharma ranks #999999 out of 332 companies in the Biotechnology industry.
Is Crescent Biopharma's EV-to-FCF too high?
Crescent Biopharma's current EV-to-FCF is -3.78. Based on the distribution chart, Crescent Biopharma ranks #999999 out of 332 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Crescent Biopharma has a GF Score™ of 10/100, reflecting its overall financial health beyond just this single metric.
How does Crescent Biopharma's EV-to-FCF compare to KYTX and ZURA?
According to the Biotechnology industry distribution chart, Crescent Biopharma ranks #999999 out of 332 companies for EV-to-FCF. This places Crescent Biopharma in the lower half of its industry. The industry median EV-to-FCF is 16.26. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 16.26, based on 332 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Crescent Biopharma and its competitors. For the Biotechnology industry, the median EV-to-FCF is 16.26 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Crescent Biopharma's current EV-to-FCF is -3.78. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Crescent Biopharma stock overvalued right now?
Crescent Biopharma (FRA:C68) has a current EV-to-FCF of -3.78. The current EV-to-FCF is -3.78. Crescent Biopharma's overall GF Score™ is 10/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For Crescent Biopharma (FRA:C68), the current EV-to-FCF is -3.78 as of Jul. 04, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Crescent Biopharma Business Description

Other Exchanges CBIO:USA
Address 300 Fifth Avenue, Waltham, MA, USA, 02451
Crescent Biopharma Inc is a biopharmaceutical company developing novel therapeutics to treat solid tumors, led by CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody. Crescent's pipeline product CR-001 has the potential to deliver improved clinical efficacy and safety over pembrolizumab. CR-001 is a new molecular entity designed to replicate the functional properties of ivonescimab, a cooperative bispecific anti-PD-1/anti-VEGF antibody in development by Akeso Biopharma and Summit Therapeutics that delivered improved efficacy in a head-to-head Phase 3 clinical trial versus Keytruda in non-small cell lung cancer. The company focuses on advancing its second and third programs, CR-002 and CR-003, which are antibody drug conjugates (ADCs) against validated oncology targets.
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€14.60
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