CRISPR Therapeutics AG (LTS:0VRQ) EV-to-FCF: -10.00 (As of Jul. 04, 2026)


LTS:0VRQ CRISPR Therapeutics AG LTS:0VRQ
46 GF Score
Price $59.25
GF Value $2.74
Valuation Significantly Overvalued
! 3 Warning Signs
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What is CRISPR Therapeutics AG EV-to-FCF?

CRISPR Therapeutics AG LTS:0VRQ 46 EV-to-FCF is -10.00 as of Jul. 04, 2026. GuruFocus rates LTS:0VRQ with a GF Score™ of 46/100 and a GF Value™ of $2.74 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 332 Biotechnology companies, CRISPR Therapeutics AG ranks worse than 301204.52% on this metric.

EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, CRISPR Therapeutics AG's Enterprise Value is $4,262.78 Mil. CRISPR Therapeutics AG's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-426.18 Mil. Therefore, CRISPR Therapeutics AG's EV-to-FCF for today is -10.00.

The historical rank and industry rank for CRISPR Therapeutics AG's EV-to-FCF or its related term are showing as below:

LTS:0VRQ' s EV-to-FCF Range Over the Past 10 Years
Min: -62.95   Med: -8.57   Max: 196.76
Current: -10

During the past 12 years, the highest EV-to-FCF of CRISPR Therapeutics AG was 196.76. The lowest was -62.95. And the median was -8.57.

LTS:0VRQ's EV-to-FCF is ranked worse than
100% of 332 companies
in the Biotechnology industry
Industry Median: 16.26 vs LTS:0VRQ: -10.00

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-07-04), CRISPR Therapeutics AG's stock price is $59.25. CRISPR Therapeutics AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-6.220. Therefore, CRISPR Therapeutics AG's PE Ratio (TTM) for today is At Loss.


CRISPR Therapeutics AG  (LTS:0VRQ) EV-to-FCF Explanation

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

CRISPR Therapeutics AG's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=59.25/-6.220
=At Loss

CRISPR Therapeutics AG's share price for today is $59.25.
CRISPR Therapeutics AG's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-6.220.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.


CRISPR Therapeutics AG EV-to-FCF Related Terms


CRISPR Therapeutics AG EV-to-FCF Historical Data

* Premium members only.

The historical data trend for CRISPR Therapeutics AG's EV-to-FCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CRISPR Therapeutics AG EV-to-FCF Chart

CRISPR Therapeutics AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-FCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only 8.05 -3.04 -13.06 -11.71 -8.79

CRISPR Therapeutics AG Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-FCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -4.23 -7.97 -13.35 -8.79 -6.88

LTS:0VRQ vs ORKA, TVTX, MANE: EV-to-FCF Comparison

For the Biotechnology subindustry, CRISPR Therapeutics AG's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CRISPR Therapeutics AG EV-to-FCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, CRISPR Therapeutics AG's EV-to-FCF distribution charts can be found below:

* The bar in red indicates where CRISPR Therapeutics AG's EV-to-FCF falls into.


LTS:0VRQ
46GF Score
CRISPR Therapeutics AG LTS:0VRQ
EV-to-FCF is just one metric. See GF Score™, valuation, warning signs, and more.
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CRISPR Therapeutics AG EV-to-FCF Calculation

CRISPR Therapeutics AG's EV-to-FCF for today is calculated as:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=4262.783/-426.176
=-10.00

CRISPR Therapeutics AG's current Enterprise Value is $4,262.78 Mil.
CRISPR Therapeutics AG's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-426.18 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-FCF →
What does a EV-to-FCF of -10.00 mean?
CRISPR Therapeutics AG (LTS:0VRQ) has a EV-to-FCF of -10.00 as of Jul. 04, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on CRISPR Therapeutics AG and its competitors. According to the industry distribution chart, CRISPR Therapeutics AG ranks #999999 out of 332 companies in the Biotechnology industry.
Is CRISPR Therapeutics AG's EV-to-FCF too high?
CRISPR Therapeutics AG's current EV-to-FCF is -10.00. Based on the distribution chart, CRISPR Therapeutics AG ranks #999999 out of 332 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, CRISPR Therapeutics AG has a GF Score™ of 46/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CRISPR Therapeutics AG's EV-to-FCF compare to ORKA and TVTX?
According to the Biotechnology industry distribution chart, CRISPR Therapeutics AG ranks #999999 out of 332 companies for EV-to-FCF. This places CRISPR Therapeutics AG in the lower half of its industry. The industry median EV-to-FCF is 16.26. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 16.26, based on 332 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on CRISPR Therapeutics AG and its competitors. For the Biotechnology industry, the median EV-to-FCF is 16.26 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. CRISPR Therapeutics AG's current EV-to-FCF is -10.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CRISPR Therapeutics AG stock overvalued right now?
Based on GuruFocus' analysis, CRISPR Therapeutics AG (LTS:0VRQ) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.74, compared to a current price of $59.25 — trading 2062.4% above its estimated fair value. The current EV-to-FCF is -10.00. CRISPR Therapeutics AG's overall GF Score™ is 46/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For CRISPR Therapeutics AG (LTS:0VRQ), the current EV-to-FCF is -10.00 as of Jul. 04, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CRISPR Therapeutics AG (LTS:0VRQ) Overvalued in 2026?

Based on GuruFocus' analysis, CRISPR Therapeutics AG stock appears to be overvalued. The current stock price of $59.25 is trading 2062.4% above its estimated GF Value™ of $2.74. GuruFocus considers CRISPR Therapeutics AG to be Significantly Overvalued.

Key valuation signals for LTS:0VRQ:

  • EV-to-FCF: -10.00
  • GF Value™: $2.74 vs. price of $59.25 (2062.4% above fair value)
  • GF Score™: 46/100 with 3 warning signs

No single metric tells the full story. See the LTS:0VRQ stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CRISPR Therapeutics AG Business Description

Address Baarerstrasse 14, Zug, CHE, 6300
Crispr Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia. The company is advancing a variety of gene editing programs in immuno-oncology, cardiovascular, and a stem cell-derived therapy to treat Type 1 diabetes.
46GF Score

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EV-to-FCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$59.25
Price
$2.74
GF Value