Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
OS TherapiesOSTX +0.26%10 EV-to-FCF is -4.36 as of Jul. 27, 2026. GuruFocus rates OSTX with a GF Score™ of 10/100. The stock has 4 warning signs investors should review. Among 343 Biotechnology companies, OS Therapies ranks worse than 291544.9% on this metric.
EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, OS Therapies's Enterprise Value is $68.30 Mil.
OS Therapies's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-15.68 Mil. Therefore, OS Therapies's EV-to-FCF for today is -4.36.
The historical rank and industry rank for OS Therapies's EV-to-FCF or its related term are showing as below:
OSTX'
s EV-to-FCF Range Over the Past 10 Years
Min: -4.36 Med: 0 Max: 0
Current: -4.36
OSTX's EV-to-FCF is ranked worse than 100% of 343
companies
in the Biotechnology industry
Industry Median: 14.79
vs OSTX: -4.36
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
OS Therapies's PE Ratio (TTM) for today is calculated as:
OS Therapies's share price for today is $1.524.
OS Therapies's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.080.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.
OS Therapies EV-to-FCF Related Terms
OS Therapies EV-to-FCF Historical Data
* Premium members only.
The historical data trend for OS Therapies's EV-to-FCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, OS Therapies's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
OS Therapies EV-to-FCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, OS Therapies's EV-to-FCF distribution charts can be found below:
* The bar in red indicates where OS Therapies's EV-to-FCF falls into.
OS Therapies's current Enterprise Value is $68.30 Mil.
OS Therapies's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-15.68 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OS Therapies (OSTX) has a EV-to-FCF of -4.36 as of Jul. 27, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on OS Therapies and its competitors. According to the industry distribution chart, OS Therapies ranks #999999 out of 343 companies in the Biotechnology industry.
Is OS Therapies' EV-to-FCF too high?
OS Therapies' current EV-to-FCF is -4.36. Based on the distribution chart, OS Therapies ranks #999999 out of 343 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, OS Therapies has a GF Score™ of 10/100, reflecting its overall financial health beyond just this single metric.
How does OS Therapies' EV-to-FCF compare to RNTX and BSEM?
According to the Biotechnology industry distribution chart, OS Therapies ranks #999999 out of 343 companies for EV-to-FCF. This places OS Therapies in the lower half of its industry. The industry median EV-to-FCF is 14.79. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 14.79, based on 343 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on OS Therapies and its competitors. For the Biotechnology industry, the median EV-to-FCF is 14.79 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OS Therapies's current EV-to-FCF is -4.36. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OS Therapies stock overvalued right now?
OS Therapies (OSTX) has a current EV-to-FCF of -4.36. The current EV-to-FCF is -4.36. OS Therapies' overall GF Score™ is 10/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For OS Therapies (OSTX), the current EV-to-FCF is -4.36 as of Jul. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
OS Therapies Inc is a clinical stage biopharmaceutical company focused on the identification, development and commercialization of treatments for Osteosarcoma (OS) and other solid tumors. The company's mission is to address the need for new treatments in cancers of the bone in children and young adults. The company has pipeline of product candidates targeting multiple indications for solid cancers including two drug technologies: (i) OST-HER2, an off-the-shelf immunotherapy, which is a type of cancer treatment that helps the immune system fight cancer and OST-tADC which is a tunable drug conjugate (tADC) platform currently in preclinical development. Each tADC contains four main components: ligand, payload cassette adaptor, linker and payload.
10GF Score
Get the complete analysis for OSTX
EV-to-FCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
OSTX has been successfully added to your 
