Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, Avalo Therapeutics's Enterprise Value is €770.43 Mil.
Avalo Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was €-51.29 Mil. Therefore, Avalo Therapeutics's EV-to-FCF for today is -15.02.
The historical rank and industry rank for Avalo Therapeutics's EV-to-FCF or its related term are showing as below:
STU:C6K0'
s EV-to-FCF Range Over the Past 10 Years
Min: -64.61 Med: -1.35 Max: 13.45
Current: -14.72
During the past 13 years, the highest EV-to-FCF of Avalo Therapeutics was 13.45. The lowest was -64.61. And the median was -1.35.
STU:C6K0's EV-to-FCF is ranked worse than 100% of 338
companies
in the Biotechnology industry
Industry Median: 15.175
vs STU:C6K0: -14.72
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Avalo Therapeutics's PE Ratio (TTM) for today is calculated as:
Avalo Therapeutics's share price for today is €15.76.
Avalo Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-4.695.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Avalo Therapeutics EV-to-FCF Related Terms
Avalo Therapeutics EV-to-FCF Historical Data
* Premium members only.
The historical data trend for Avalo Therapeutics's EV-to-FCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
STU:C6K0 vs SANA, ANRO, REPL: EV-to-FCF Comparison
For the Biotechnology subindustry, Avalo Therapeutics's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Avalo Therapeutics EV-to-FCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Avalo Therapeutics's EV-to-FCF distribution charts can be found below:
* The bar in red indicates where Avalo Therapeutics's EV-to-FCF falls into.
Avalo Therapeutics's current Enterprise Value is €770.43 Mil.
Avalo Therapeutics's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-51.29 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Avalo Therapeutics (STU:C6K0) has a EV-to-FCF of -15.02 as of Jul. 23, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Avalo Therapeutics and its competitors. According to the industry distribution chart, Avalo Therapeutics ranks #999999 out of 338 companies in the Biotechnology industry.
Is Avalo Therapeutics' EV-to-FCF too high?
Avalo Therapeutics' current EV-to-FCF is -15.02. Based on the distribution chart, Avalo Therapeutics ranks #999999 out of 338 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Avalo Therapeutics has a GF Score™ of 44/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Avalo Therapeutics' EV-to-FCF compare to SANA and ANRO?
According to the Biotechnology industry distribution chart, Avalo Therapeutics ranks #999999 out of 338 companies for EV-to-FCF. This places Avalo Therapeutics in the lower half of its industry. The industry median EV-to-FCF is 15.18. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 15.18, based on 338 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Avalo Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-FCF is 15.18 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Avalo Therapeutics's current EV-to-FCF is -15.02. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Avalo Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Avalo Therapeutics (STU:C6K0) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.03, compared to a current price of €15.76 — trading 52433.3% above its estimated fair value. The current EV-to-FCF is -15.02. Avalo Therapeutics' overall GF Score™ is 44/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For Avalo Therapeutics (STU:C6K0), the current EV-to-FCF is -15.02 as of Jul. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Avalo Therapeutics (STU:C6K0) Overvalued in 2026?
Based on GuruFocus' analysis, Avalo Therapeutics stock appears to be overvalued.
The current stock price of €15.76 is trading 52433.3% above its estimated GF Value™ of €0.03.
GuruFocus considers Avalo Therapeutics to be Significantly Overvalued.
Key valuation signals for STU:C6K0:
EV-to-FCF: -15.02
GF Value™: €0.03 vs. price of €15.76 (52433.3% above fair value)
No single metric tells the full story. See the STU:C6K0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Avalo Therapeutics Inc is a clinical stage biotechnology company fully dedicated to developing IL-1B-based treatments for immune-mediated inflammatory diseases. The company's asset is Abdakibart (AVTX-009) an anti-IL-1B monoclonal antibody ("mAb"), targeting inflammatory diseases. Avalos pipeline also includes quisovalimab (anti-LIGHT mAb) and AVTX-008 (BTLA agonist fusion protein), AVTX-006 and AVTX-913.
44GF Score
Get the complete analysis for STU:C6K0
EV-to-FCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
STU:C6K0 has been successfully added to your 
