Design TherapeuticsDSGN +6.68%33 PB Ratio is 4.48 as of Jul. 06, 2026. GuruFocus rates DSGN with a GF Score™ of 33/100. The stock has 2 warning signs investors should review. Among 1,230 Biotechnology companies, Design Therapeutics ranks worse than 65.85% on this metric.
The historical rank and industry rank for Design Therapeutics's PB Ratio or its related term are showing as below:
DSGN'
s PB Ratio Range Over the Past 10 Years
Min: 0 Med: 0 Max: 4.48
Current: 4.48
During the past 7 years, Design Therapeutics's highest PB Ratio was 4.48. The lowest was 0.00. And the median was 0.00.
DSGN's PB Ratio is ranked worse than 65.85% of 1230
companies
in the Biotechnology industry
Industry Median: 2.98
vs DSGN: 4.48
During the past 12 months, Design Therapeutics's average Book Value Per Share Growth Rate was -17.50% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -15.60% per year.
During the past 7 years, the highest 3-Year average Book Value Per Share Growth Rate of Design Therapeutics was -14.80% per year. The lowest was -15.60% per year. And the median was -15.20% per year.
Back to Basics: PB Ratio
Design Therapeutics (NAS:DSGN) PB Ratio Explanation
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Design Therapeutics PB Ratio Related Terms
Design Therapeutics PB Ratio Historical Data
* Premium members only.
The historical data trend for Design Therapeutics's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Design Therapeutics's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Design Therapeutics PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Design Therapeutics's PB Ratio distribution charts can be found below:
* The bar in red indicates where Design Therapeutics's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Design Therapeutics (DSGN) has a PB Ratio of 4.48 as of Jul. 06, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Design Therapeutics and its competitors. According to the industry distribution chart, Design Therapeutics ranks #810 out of 1230 companies in the Biotechnology industry, placing it in the top 65.9%.
Is Design Therapeutics' PB Ratio too high?
Design Therapeutics' current PB Ratio is 4.48. The Biotechnology industry median PB Ratio is 2.98. Design Therapeutics' value of 4.48 is 50.3% above this industry median. Based on the distribution chart, Design Therapeutics ranks #810 out of 1230 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Design Therapeutics has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Design Therapeutics' PB Ratio compare to SPRY and GERN?
According to the Biotechnology industry distribution chart, Design Therapeutics ranks #810 out of 1230 companies for PB Ratio. This places Design Therapeutics in the lower half of its industry. The industry median PB Ratio is 2.98. Design Therapeutics' value of 4.48 is 50.3% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.98, based on 1,230 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Design Therapeutics's current PB Ratio of 4.48 is 50.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Design Therapeutics and its competitors. For the Biotechnology industry, the median PB Ratio is 2.98 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Design Therapeutics's current PB Ratio is 4.48. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Design Therapeutics stock overvalued right now?
Design Therapeutics (DSGN) has a current PB Ratio of 4.48. The current PB Ratio is 4.48 and 50.3% above the Biotechnology industry median of 2.98. Design Therapeutics' overall GF Score™ is 33/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Design Therapeutics (DSGN), the current PB Ratio is 4.48 as of Jul. 06, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Design Therapeutics Inc is a clinical-stage biopharmaceutical company pioneering the research and development of GeneTAC molecules, which are a novel class of small-molecule gene targeted chimera therapeutic candidates designed to be disease-modifying by addressing the underlying cause of diseases caused by inherited nucleotide repeat expansion mutations. Its pipeline includes Friedreich Ataxia, FECD, DM1, and Huntington's Disease. The company operates in one operating and reportable segment focused on utilizing the company's proprietary GeneTAC platform to design and develop therapeutic candidates for inherited diseases driven by nucleotide repeat expansion.
33GF Score
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