AEMD (Aethlon Medical) ROE %: -129.94% (As of Mar. 2026)


AEMD Aethlon Medical Inc AEMD
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What is Aethlon Medical ROE %?

Aethlon Medical AEMD -10.29% 23 ROE % is -129.94% as of Mar. 2026. GuruFocus rates AEMD with a GF Score™ of 23/100. The stock has 1 warning sign investors should review. Among 799 Medical Devices & Instruments companies, Aethlon Medical ranks worse than 92.24% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Aethlon Medical's annualized net income for the quarter that ended in Mar. 2026 was $-7.54 Mil. Aethlon Medical's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $5.80 Mil. Therefore, Aethlon Medical's annualized ROE % for the quarter that ended in Mar. 2026 was -129.94%.

The historical rank and industry rank for Aethlon Medical's ROE % or its related term are showing as below:

AEMD' s ROE % Range Over the Past 10 Years
Min: -652.85   Med: -130.05   Max: -74.73
Current: -138.09

During the past 13 years, Aethlon Medical's highest ROE % was -74.73%. The lowest was -652.85%. And the median was -130.05%.

AEMD's ROE % is ranked worse than
92.24% of 799 companies
in the Medical Devices & Instruments industry
Industry Median: 2.42 vs AEMD: -138.09

Aethlon Medical  (NAS:AEMD) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-7.536/5.7995
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-7.536 / 0)*(0 / 7.195)*(7.195 / 5.7995)
=Net Margin %*Asset Turnover*Equity Multiplier
=N/A %*0*1.2406
=ROA %*Equity Multiplier
=N/A %*1.2406
=-129.94 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-7.536/5.7995
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-7.536 / -7.536) * (-7.536 / -7.716) * (-7.716 / 0) * (0 / 7.195) * (7.195 / 5.7995)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1 * 0.9767 * N/A % * 0 * 1.2406
=-129.94 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Aethlon Medical ROE % Related Terms


Aethlon Medical ROE % Historical Data

* Premium members only.

The historical data trend for Aethlon Medical's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Aethlon Medical ROE % Chart

Aethlon Medical Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
ROE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -78.42 -74.73 -117.22 -245.88 -142.88

Aethlon Medical Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -529.08 -164.90 -129.73 -129.58 -129.94

AEMD vs RMSL, BTCY, IVF: ROE % Comparison

For the Medical Devices subindustry, Aethlon Medical's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Aethlon Medical ROE % vs Medical Devices & Instruments Industry

For the Medical Devices & Instruments industry and Healthcare sector, Aethlon Medical's ROE % distribution charts can be found below:

* The bar in red indicates where Aethlon Medical's ROE % falls into.


AEMD
23GF Score
Aethlon Medical Inc AEMD
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Aethlon Medical ROE % Calculation

Aethlon Medical's annualized ROE % for the fiscal year that ended in Mar. 2026 is calculated as

ROE %=Net Income (A: Mar. 2026 )/( (Total Stockholders Equity (A: Mar. 2025 )+Total Stockholders Equity (A: Mar. 2026 ))/ count )
=-7.151/( (5.124+4.886)/ 2 )
=-7.151/5.005
=-142.88 %

Aethlon Medical's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-7.536/( (6.713+4.886)/ 2 )
=-7.536/5.7995
=-129.94 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -129.94% mean?
Aethlon Medical (AEMD) has a ROE % of -129.94% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Aethlon Medical and its competitors. According to the industry distribution chart, Aethlon Medical ranks #737 out of 799 companies in the Medical Devices & Instruments industry, placing it in the top 92.2%.
Is Aethlon Medical's ROE % too high?
Aethlon Medical's current ROE % is -129.94%. Based on the distribution chart, Aethlon Medical ranks #737 out of 799 companies in the Medical Devices & Instruments industry, which is in the bottom quartile relative to peers. Overall, Aethlon Medical has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Aethlon Medical's ROE % compare to RMSL and BTCY?
According to the Medical Devices & Instruments industry distribution chart, Aethlon Medical ranks #737 out of 799 companies for ROE %. This places Aethlon Medical in the lower half of its industry. The industry median ROE % is 2.42. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Medical Devices & Instruments company?
The median ROE % among Medical Devices & Instruments companies is 2.42, based on 799 companies in the industry. Companies in the top quartile (top 25%) have a ROE % significantly above this median, while those in the bottom quartile fall well below. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Aethlon Medical and its competitors. For the Medical Devices & Instruments industry, the median ROE % is 2.42 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Aethlon Medical's current ROE % is -129.94%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Aethlon Medical stock overvalued right now?
Aethlon Medical (AEMD) has a current ROE % of -129.94%. The current ROE % is -129.94%. Aethlon Medical's overall GF Score™ is 23/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Aethlon Medical (AEMD), the current ROE % is -129.94% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Aethlon Medical Business Description

Address 11555 Sorrento Valley Road, Suite 203, San Diego, CA, USA, 92121
Aethlon Medical Inc is a medical therapeutic company focused on developing the Hemopurifier (HP), a clinical-stage investigational immunotherapeutic device designed to address unmet needs in oncology, life-threatening infectious diseases, organ transplantation and other disease states in which extracellular vesicles (EVs) contribute to disease progression. The Hemopurifier utilizes a proprietary lectin-based technology to bind and remove enveloped viruses and EVs from biological fluids. EVs have been associated with immune suppression, metastasis, and resistance to therapy in cancer, as well as progression of severe infectious diseases. The Company operates as a single reportable segment.
23GF Score

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