Insider List

40/Page

Total 36

Insider Name
3x5 Rivervest Fund Ii, L.p.
3x5 Rivervest Fund Ii-b, L.p.
Adam Tomasi
Alta Partners Management Viii, Llc
Alta Partners Nextgen Fund I Management, Llc
Alta Partners Nextgen Fund I, L.p.
Alta Partners Viii, L.p.
Amy L Ladd
Craig A. Paterson
Daniel Janney
Dolca Thomas
Everett Rand Sutherland
Farah Champsi
Graham Neil Murray Hamilton
Guy P Nohra
Harlan Baird Radford
Jeremy Green
John P Mckearn
Leo Redmond
Margaret Nell Fitzgerald
Mark Asbury
Natalie C. Holles
Paul Edward Walker
Peter A Hudson
Rasmussen Henrik S Md
Redmile Group, Llc
Rivervest Venture Fund Ii (ohio), L.p.
Rivervest Venture Fund Ii L P
Rivervest Venture Fund Iii (ohio), L.p.
Rivervest Venture Fund Iii, L.p.
Robert Alexander
Robert E Andreatta
Robert J More
Roche Finance Ltd
Roche Holding Ltd
Steven P James

Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
Insider Name	Latest Transaction Date	Aggregate Performance						Aggregate Performance Relative to S&P 500						Companys
Insider Name	Latest Transaction Date	1M	3M	6M	1Y	2Y	3Y	1M	3M	6M	1Y	2Y	3Y	Companys
3x5 Rivervest Fund Ii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
3x5 Rivervest Fund Ii-b, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
Adam Tomasi	2021-06-04	-	-	-	-	-	-	-	-	-	-	-	-	ALLK ZSPH
Alta Partners Management Viii, Llc		-	-	-	-	-	-	-	-	-	-	-	-	ALLK STRO EVFM ZSPH ATYR TRVN ... AGTC ESPR IMDZ
Alta Partners Nextgen Fund I Management, Llc		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
Alta Partners Nextgen Fund I, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
Alta Partners Viii, L.p.	2018-07-23	21.480	21.480	122.810	0.610	56.030	16.360	16.890	51.310	117.320	-10.480	47.440	4.590	ALLK STRO EVFM ZSPH ATYR ESPR ... TRVN AGTC IMDZ
Amy L Ladd	2025-09-04	-	-	-	-	-	-	-	-	-	-	-	-	ISRG ALLK
Craig A. Paterson		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
Daniel Janney	2022-09-21	18.350	18.350	61.690	-2.850	27.050	4.460	15.930	37.290	56.200	-16.230	15.910	-4.990	KRYS ESPR ALLK STRO VIVE EVFM ... ZSPH ATYR KALV TRVN AGTC IMDZ AERI ELLI TLPH RPTP NGSX DVAX CUTRQ AVDL TYRA
Dolca Thomas	2022-09-02	-7.350	-7.350	7.490	-	-	-	1.280	7.270	6.040	-	-	-	ADRO PRNB KDNY EQ ALLK
Everett Rand Sutherland		-	-	-	-	-	-	-	-	-	-	-	-	KRYS ALLK UPB
Farah Champsi	2017-06-16	-	-	-	-	-	-	-	-	-	-	-	-	ALLK STRO KITE EVFM ZSPH ATYR ... TRVN AGTC ESPR IMDZ SCYX CARA CMRX PTLA AEGR SNSS CORT MTEMQ RPTP NGSX RIGL VIRX PHIC PHICU TVRD
Graham Neil Murray Hamilton		-	-	-	-	-	-	-	-	-	-	-	-	ZURA ALLK
Guy P Nohra	2011-02-16	-17.220	-17.220	-17.690	-29.250	13.170	40.350	-11.280	-13.410	-6.950	-30.880	6.530	29.120	ALLK STRO EVFM ZSPH ATYR KALV ... TRVN AGTC ESPR IMDZ AERI TLPH ELLI RPTP NGSX CUTRQ DVAX BGMS RIGL AVDL BVS
Harlan Baird Radford	2024-06-28	-	-	-	-	-	-	-	-	-	-	-	-	EBAY ALLK OMCL
Jeremy Green		-	-	-	-	-	-	-	-	-	-	-	-	STTK IGMS KYMR ALVR ANNX NRIX ... RPTX FATE PLRX NLTX BEAM CABA ALDR APRE BCEL AKRO STOK HOOK XERS TCRR VAPO GRTSQ REPL ALLK SYRS FOLD MDVLQ ABSI TRDA AUGX SNCE IVVD VERV ZYME RYZB NGNE ATRA KLRS ADCT
John P Mckearn	2018-07-23	7.470	7.470	18.050	-10.110	52.140	31.240	5.690	29.640	24.050	-17.180	44.790	14.990	ALLK OTIC
Leo Redmond		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
Margaret Nell Fitzgerald	2023-09-08	18.600	18.600	101.740	59.300	19.320	-	21.940	29.260	86.790	37.970	-1.360	-	ALLK CDXS
Mark Asbury		-	-	-	-	-	-	-	-	-	-	-	-	ALLK ZSPH
Natalie C. Holles	2024-05-09	-	-	-	-	-	-	-	-	-	-	-	-	RUBY BOLD ALLK DAWN THRD
Paul Edward Walker	2024-09-16	-0.570	-0.570	-12.530	-43.530	-40.990	-33.810	-1.660	-6.380	-21.740	-56.620	-54.010	-43.850	MTCR GNCAQ AKUS TCON ALLK TRVI ... BDTX RGLS MIRM MRKR TSRO SVRA NEUE GLUE GGNNQ KRRO MBX
Peter A Hudson	2020-03-13	46.790	46.790	231.770	459.170	164.150	-	44.920	120.850	208.530	413.860	139.540	-	TVTY ALLK TYRA
Rasmussen Henrik S Md	2021-04-01	-	-	-	-	-	-	-	-	-	-	-	-	ALLK ZSPH VXRT
Redmile Group, Llc	2024-12-20	8.170	8.170	-2.300	15.150	2.390	-1.940	6.930	1.910	-7.050	1.110	-9.160	-13.640	STTK IGMS KYMR ALVR ANNX NRIX ... RPTX FATE PLRX NLTX BEAM CABA ALDR APRE BCEL AKRO STOK HOOK XERS TCRR VAPO GRTSQ REPL ALLK SYRS FOLD MDVLQ ABSI TRDA AUGX SNCE IVVD VERV ZYME RYZB NGNE ATRA KLRS ADCT
Rivervest Venture Fund Ii (ohio), L.p.	2018-07-23	7.470	7.470	18.050	-10.110	52.140	31.240	5.690	29.640	24.050	-17.180	44.790	14.990	ALLK ZSPH
Rivervest Venture Fund Ii L P		-	-	-	-	-	-	-	-	-	-	-	-	ALLK ZSPH
Rivervest Venture Fund Iii (ohio), L.p.	2021-04-09	17.950	17.950	-31.970	-76.350	-55.680	-52.850	15.310	-10.320	-44.260	-94.310	-56.200	-60.600	SPRB ALLK RPHM OKUR
Rivervest Venture Fund Iii, L.p.		-	-	-	-	-	-	-	-	-	-	-	-	SPRB ALLK RPHM OKUR
Robert Alexander	2021-05-17	-	-	-	-	-	-	-	-	-	-	-	-	ALLK ALNAQ ZSPH
Robert E Andreatta		-	-	-	-	-	-	-	-	-	-	-	-	ALLK
Robert J More	2021-09-17	-14.290	-14.290	-24.400	-71.030	-51.150	-37.030	-13.250	-23.590	-28.100	-72.710	-53.680	-35.210	VIR ALLK SNNAQ GKOS OREXQ PRTK ... VNDA NUVA TYRA
Roche Finance Ltd		-	-	-	-	-	-	-	-	-	-	-	-	PAND FMI ALLK RNTX SENS TRDA ... JSPR ALGS
Roche Holding Ltd	2020-07-21	-0.220	-0.220	-7.750	-56.780	-76.150	-54.560	-3.280	-15.370	-23.280	-69.280	-87.030	-63.340	PAND ONCE FMI ALLK RNTX SENS ... TRDA JSPR ALGS
Steven P James	2021-09-28	-	-	-	-	-	-	-	-	-	-	-	-	ALLK CASC OCRX EXEL

40/Page

Total 36

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