Spruce Biosciences Inc logo

Spruce Biosciences Inc

NEW
NAS:SPRB (USA)   Ordinary Shares
$ 52.51 -0.035 (-0.07%) 12:08 AM EST
At Loss
P/B:
2.08
Market Cap:
$ 144.52M
Enterprise V:
$ 97.56M
Volume:
68.84K
Avg Vol (2M):
65.26K
Trade In:
Volume:
68.84K
At Loss
Avg Vol (2M):
65.26K

Business Description

Spruce Biosciences Inc logo
Spruce Biosciences Inc
NAICS : 541714 SIC : 2833
ISIN : US85209E2081

Share Class Description:

SPRB: Ordinary Shares

Total Employee Number:

8
Description
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
Name Current Vs Industry Vs History
Cash-To-Debt
7.59
Equity-to-Asset
0.62
Debt-to-Equity
0.21
Debt-to-EBITDA
-0.2
Piotroski F-Score
2/9
0
1
2
3
4
5
6
7
8
9
WACC vs ROIC
WACC
ROIC
Name Current Vs Industry Vs History
5-Day RSI
45.78
9-Day RSI
50.34
14-Day RSI
49.99
3-1 Month Momentum %
-30.07
6-1 Month Momentum %
-45.64
12-1 Month Momentum %
801.69

Liquidity Ratio

Name Current Vs Industry Vs History
Current Ratio
4.67
Quick Ratio
4.67
Cash Ratio
4.59

Dividend & Buy Back

Name Current Vs Industry Vs History
3-Year Average Share Buyback Ratio
-63.3
Shareholder Yield %
0.16

Profitability Rank

Name Current Vs Industry Vs History
ROE %
-167.45
ROA %
-104.49
ROIC %
-1041.4
3-Year ROIIC %
-516.05
ROC (Joel Greenblatt) %
-4970.42
ROCE %
-148.29
Moat Score
4
Tariff Resilience Score
8

Financials (Next Earnings Date:2026-08-14 Est.)

SPRB's 30-Y Financials
Income Statement Breakdown FY
Not Enough Data
Balance Sheet Breakdown
Not Enough Data
Cashflow Statement Breakdown
Not Enough Data

Operating Revenue by Business Segment

Operating Revenue by Geographic Region

Historical Operating Revenue by Business Segment

Historical Operating Revenue by Geographic Region

5-Step DuPont Analysis as of
Not Enough Data

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Performance

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Log
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To

Annualized Return %  

Symbol
1 Week
1 Month
3 Months
6 Months
YTD
1 Year
3 Years
5 Years
10 Years

Total Annual Return %  

Symbol
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017

Spruce Biosciences Inc Executives

Details

Valuation Chart

Year:

Analyst Estimate

Key Statistics

Name Value
Revenue (TTM) (Mil $)
EPS (TTM) ($) -37.608
Beta 3.9181
3-Year Sharpe Ratio 0.51
3-Year Sortino Ratio 4.14
Volatility % 1132.51
14-Day RSI 49.99
14-Day ATR ($) 3.722122
20-Day SMA ($) 51.48625
12-1 Month Momentum % 801.69
52-Week Range ($) 4.962 - 240
Shares Outstanding (Mil) 2.75

Piotroski F-Score Details

Year:
Component Result
Piotroski F-Score 2
Positive ROA
Positive CFROA
Higher ROA yoy
CFROA > ROA
Lower Leverage yoy
Higher Current Ratio yoy
Less Shares Outstanding yoy
Higher Gross Margin yoy
Higher Asset Turnover yoy

Spruce Biosciences Inc Filings

Filing Date Document Date Form
No Filing Data

Spruce Biosciences Inc Stock Events

Financials Calendars
Event Date Price ($)
Third quarter earnings results for 2026 2026-11-10 In 128 days
Second quarter earnings results for 2026 2026-08-14 In 40 days
Jefferies Global Healthcare Conference in New York 2026-06-04 11:05 49.05 (+2.00%)
General meeting for 2026 2026-05-21 10:00 51.52 (+3.26%)
First quarter earnings results for 2026 2026-05-13 56.67 (+1.64%)
The Citizens Life Sciences Conference 2026-03-10 12:30 62.11 (+18.37%)
Leerink Global Healthcare Conference 2026-03-09 11:20 55.87 (+7.17%)
Annual report for 2025 2026-03-09 55.87 (+7.17%)
Fourth quarter earnings results for 2025 2026-03-09 55.87 (+7.17%)
Oppenheimer 36th Annual Healthcare Life Sciences Conference 2026-02-25 15:20 59.41 (+9.98%)
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Spruce Biosciences Inc Frequently Asked Questions

What is Spruce Biosciences Inc(SPRB)'s stock price today?
The current price of SPRB is $52.51. The 52 week high of SPRB is $240.00 and 52 week low is $4.96.
When is next earnings date of Spruce Biosciences Inc(SPRB)?
The next earnings date of Spruce Biosciences Inc(SPRB) is 2026-08-14 Est..
Does Spruce Biosciences Inc(SPRB) pay dividends? If so, how much?
Spruce Biosciences Inc(SPRB) does not pay dividend.

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