Data Presented from the MIRROR Randomized Controlled Trial Demonstrate KRYSTEXXA® (pegloticase injection) Plus Methotrexate Resulted in Significant Improvement in Efficacy and Safety (Infusion Reactions) Compared to KRYSTEXXA Monotherapy

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Jun 01, 2022

Horizon Therapeutics plc (Nasdaq: HZNP) today announced the presentation of new KRYSTEXXA® (pegloticase injection) datasets on the primary endpoint results from the MIRROR randomized clinical trial and analyses of the pharmacokinetics of KRYSTEXXA plus methotrexate. Additional presentations by Horizon during The+EULAR+2022+European+Congress+of+Rheumatology, June 1 – 4 in Copenhagen, include the exploratory findings from the PROTECT trial of KRYSTEXXA with immunomodulation in kidney transplant patients and the impact of chronic gout refractory to conventional therapies (uncontrolled gout).