Tempest Therapeutics Reports Q4 Net Loss Per Share of $1.50, Missing Analyst Estimate of -$0.27; Revenue at $0.00 Million

Key Developments and Financial Overview

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Mar 27, 2025
Summary
  • Cash Position: Ended 2024 with $30.3 million in cash and cash equivalents, down from $39.2 million at the end of 2023, primarily due to operating activities.
  • Net Loss: Reported a net loss of $41.8 million for 2024, compared to $29.5 million in 2023, reflecting increased research and development expenses.
  • Earnings Per Share (EPS): Recorded a net loss per share of $1.50, compared to $1.91 in the previous year, indicating a narrower loss per share despite higher overall net loss.
  • Research and Development Expenses: Increased to $28.5 million from $17.5 million in 2023, driven by costs associated with advancing clinical trials.
  • General and Administrative Expenses: Rose to $13.6 million from $11.7 million in 2023, mainly due to higher stock-based compensation and legal expenses.
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On March 27, 2025, Tempest Therapeutics Inc (TPST, Financial) released its 8-K filing detailing the financial results for the year ending 2024. Tempest Therapeutics, a clinical-stage biotechnology company, focuses on developing small molecule therapeutics to treat cancer by directly killing tumor cells and activating tumor-specific immunity. The company's key product candidates include TPST-1120 and TPST-1495, which are in clinical stages.

Performance and Challenges

Tempest Therapeutics reported a net loss of $41.8 million for 2024, translating to a net loss per share of $1.50. This performance fell short of the analyst estimate of -$1.38 per share. The company's revenue remained at $0.00 million, consistent with the annual estimate. The increased net loss compared to 2023, where the net loss was $29.5 million, highlights the financial challenges faced by the company, primarily due to increased research and development expenses.

Financial Achievements and Industry Importance

Despite the financial challenges, Tempest Therapeutics achieved significant milestones in 2024. The company received both Orphan Drug and Fast Track designations for Amezalpat (TPST-1120) from the FDA for treating hepatocellular carcinoma (HCC). Additionally, an agreement with Roche was announced to advance Amezalpat combination therapy into a pivotal Phase 3 trial. These achievements are crucial for a biotechnology company as they enhance the potential for regulatory approval and market entry, which are vital for long-term success.

Financial Statements Overview

Tempest Therapeutics ended 2024 with $30.3 million in cash and cash equivalents, a decrease from $39.2 million at the end of 2023. This reduction was primarily due to cash used in operating activities, partially offset by proceeds from the issuance of common stock. The company's research and development expenses increased to $28.5 million from $17.5 million in 2023, reflecting the costs associated with advancing clinical trials. General and administrative expenses also rose to $13.6 million from $11.7 million, driven by increased stock-based compensation and legal expenses.

Financial Metric 2024 2023
Cash and Cash Equivalents $30.3 million $39.2 million
Net Loss $41.8 million $29.5 million
Research and Development Expenses $28.5 million $17.5 million
General and Administrative Expenses $13.6 million $11.7 million

Analysis and Commentary

Tempest Therapeutics' financial results reflect the typical challenges faced by clinical-stage biotechnology companies, where high research and development costs are necessary to advance promising drug candidates. The company's strategic partnerships and regulatory achievements are positive indicators of its potential to bring innovative cancer treatments to market. However, the increased net loss and cash burn rate highlight the need for careful financial management and potential future funding to sustain operations and continue clinical advancements.

“2024 was another year filled with significant progress and milestone achievements that position Tempest for a successful future,” said Stephen Brady, president and chief executive officer of Tempest.

Overall, while Tempest Therapeutics has made significant strides in its clinical programs, the financial results underscore the importance of securing additional resources to support ongoing and future trials. Investors and stakeholders will be keenly watching the company's ability to manage its financial health while advancing its promising therapeutic candidates.

Explore the complete 8-K earnings release (here) from Tempest Therapeutics Inc for further details.