Why Apellis Pharmaceuticals (APLS) Stock is Declining

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May 07, 2025
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Apellis Pharmaceuticals (APLS, Financial) saw a significant decline in its stock price by 5.91%, closing at $17.99. The drop came in response to a disappointing quarterly earnings report, which did not meet analyst expectations.

For the first quarter, Apellis reported revenues of $166.8 million, with U.S. product sales contributing nearly $150 million. This represents a 3% decrease from the same period last year. The sales were led by the drug Syfovre, generating over $130 million, followed by Empaveli, which brought in almost $20 million.

The company's net loss has widened, reaching over $92 million, equivalent to $0.74 per share, compared to $86 million in the same quarter last year, as per GAAP standards. CEO Cedric Francois attributed the revenue shortfall to external challenges such as funding shortages at third-party co-pay assistance programs and unforeseen reductions in total channel inventory.

The stock currently trades with a Price-to-Book (P/B) ratio of 9.78, which is near its one-year low. This suggests a potential value opportunity, but caution is advised due to multiple warning signs such as poor financial strength and insider selling activity. The GF Value indicates a possible value trap, prompting investors to think twice before investing. For a detailed valuation, visit the GF Value page for APLS.

Apellis's stock has been volatile, with significant declines over recent periods: a 59.02% fall over the past year and a 43.62% decrease year-to-date. The company's financial health is rated poorly, with an Altman Z-score signaling distress. Additionally, insider transactions over the last three months include three selling events, with no purchases, totaling 6,115 shares sold.

Despite these challenges, Apellis's growth prospects in the biotechnology sector remain notable. The company is focused on the discovery, development, and commercialization of innovative treatments for diseases with unmet needs. However, potential investors should weigh the high-risk factors against the growth potential.

Disclosures

I/We may personally own shares in some of the companies mentioned above. However, those positions are not material to either the company or to my/our portfolios.