Dyne Therapeutics (DYN) Boosted by DYNE-101 Program Updates | DYN Stock News

Jun 17, 2025

Dyne Therapeutics (DYN, Financial) revealed significant changes to its DYNE-101 program targeting myotonic dystrophy type 1. The company revised the protocol for the ACHIEVE trial's registrational expansion cohort, opting to use video hand opening time as its primary endpoint. This modification allows for a cohort increase to 60 participants, providing robust assumptions for the video-based measure and enabling the detection of trends in secondary metrics. An analyst from H.C. Wainwright sees this focus on video hand opening time as promising for Dyne’s strategy, both clinically and commercially. The analyst has maintained a Buy rating on Dyne shares, with a price target set at $38.

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