Business Description
Spyre Therapeutics Inc
NAICS : 325412
SIC : 2834
ISIN : US00773J2024
Total Employee Number:
112Compare
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Traded in other countries / regions
SYRE.USA3920.Germany Index Membership
Russell 2000Russell 3000Russell 2000 IPO Date
2016-04-07Description
Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting ?4?7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
Financial Strength
9/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
Cash-To-Debt | No Debt | |||||
Equity-to-Asset | 0.94 | |||||
Interest Coverage | No Debt | |||||
Piotroski F-Score | 3/9 | |||||
WACC vs ROIC | ||||||
Growth Rank
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
3-Year EBITDA Growth Rate | 48.1 | |||||
3-Year EPS without NRI Growth Rate | 55.9 | |||||
3-Year FCF Growth Rate | 51.9 | |||||
3-Year Book Growth Rate | -28.1 | |||||
Future 3-5Y EPS without NRI Growth Rate Estimate Industry Rank | -25.85 |
Momentum Rank
3/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
5-Day RSI | 12.91 | |||||
9-Day RSI | 25.83 | |||||
14-Day RSI | 35.63 | |||||
3-1 Month Momentum % | 38.62 | |||||
6-1 Month Momentum % | 132.41 | |||||
12-1 Month Momentum % | 497.85 |
Liquidity Ratio
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
Current Ratio | 18.53 | |||||
Quick Ratio | 18.53 | |||||
Cash Ratio | 18.09 |
Dividend & Buy Back
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
3-Year Average Share Buyback Ratio | -210.4 | |||||
Shareholder Yield % | -5.58 |
Profitability Rank
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
ROE % | -26.33 | |||||
ROA % | -23.8 | |||||
ROIC % | -668.03 | |||||
3-Year ROIIC % | -843.51 | |||||
ROCE % | -39.65 | |||||
Moat Score | 4 | |||||
Tariff Resilience Score | 6 |
GF Value Rank
2/10
| Name | Current | Vs Industry | Vs History | |||
|---|---|---|---|---|---|---|
PB Ratio | 8.34 | |||||
Price-to-Tangible-Book | 8.34 | |||||
EV-to-EBIT | -25.69 | |||||
EV-to-EBITDA | -25.69 | |||||
EV-to-Forward-Revenue | 30.91 | |||||
EV-to-FCF | -33.36 | |||||
| Price-to-Net-Current-Asset-Value | 8.34 | |||||
| Price-to-Net-Cash | 7.42 | |||||
Earnings Yield (Greenblatt) % | -3.89 | |||||
FCF Yield % | -2.62 |
Operating Revenue by Business Segment
Operating Revenue by Geographic Region
Historical Operating Revenue by Business Segment
Historical Operating Revenue by Geographic Region
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Performance
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Annualized Return % Â
Total Annual Return % Â
Spyre Therapeutics Inc Executives
DetailsGF Valueâ„¢
Analyst Estimate
Key Statistics
| Name | Value | ||
|---|---|---|---|
| Revenue (TTM) (Mil $) | |||
| EPS (TTM) ($) | -2.049 | ||
| Beta | 1.9848 | ||
| 3-Year Sharpe Ratio | 1.2 | ||
| 3-Year Sortino Ratio | 2.79 | ||
| Volatility % | 62.36 | ||
| 14-Day RSI | 35.63 | ||
| 14-Day ATR ($) | 5.817666 | ||
| 20-Day SMA ($) | 102.87425 | ||
| 12-1 Month Momentum % | 497.85 | ||
| 52-Week Range ($) | 14.505 - 110.175 | ||
| Shares Outstanding (Mil) | 88.17 |
Piotroski F-Score Details
Year:
| Component | Result | ||
|---|---|---|---|
| Piotroski F-Score | 3 | ||
| Positive ROA | |||
| Positive CFROA | |||
| Higher ROA yoy | |||
| CFROA > ROA | |||
| Lower Leverage yoy | |||
| Higher Current Ratio yoy | |||
| Less Shares Outstanding yoy | |||
| Higher Gross Margin yoy | |||
| Higher Asset Turnover yoy |
Spyre Therapeutics Inc Filings
| Filing Date | Document Date | Form | ||
|---|---|---|---|---|
| No Filing Data | ||||
Spyre Therapeutics Inc Stock Events
| Event | Date | Price ($) | ||
|---|---|---|---|---|
| Annual report for 2026 | 2027-02-19 | In 172 days | ||
| Fourth quarter earnings results for 2026 | 2027-02-19 | In 172 days | ||
| Third quarter earnings results for 2026 | 2026-11-04 | In 65 days | ||
| Second quarter earnings results for 2026 | 2026-08-04 | 94.93 (-2.29%) | ||
| Guidance call for 2026 | 2026-06-08 10:00 | 73.65 (-5.30%) | ||
| Guidance call for 2026 | 2026-06-03 12:15 | 69.16 (-1.19%) | ||
| General meeting for 2026 | 2026-05-27 12:00 | 73.65 (-1.63%) | ||
| First quarter earnings results for 2026 | 2026-05-05 | 69.13 (+1.27%) | ||
| Spyre Therapeutics SPY001 Part A Induction Topline Results | 2026-04-13 08:00 | 51.29 (-0.21%) | ||
| Leerink Global Healthcare Conference | 2026-03-09 08:40 | 40.15 (+0.40%) |
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Spyre Therapeutics Inc Frequently Asked Questions
What is Spyre Therapeutics Inc(SYRE)'s stock price today?
The current price of SYRE is $90.39. The 52 week high of SYRE is $110.18 and 52 week low is $14.51.
When is next earnings date of Spyre Therapeutics Inc(SYRE)?
The next earnings date of Spyre Therapeutics Inc(SYRE) is 2026-11-04 Est..
Does Spyre Therapeutics Inc(SYRE) pay dividends? If so, how much?
Spyre Therapeutics Inc(SYRE) does not pay dividend.
Press Release
Articles on Spyre Therapeutics Inc
Spyre Therapeutics (SYRE) Reports Positive Phase 2 SKYWAY RA Sub-Study Results Amid High Valuation
6 days ago
Headlines
See More- 1
Aug 26, 2026
At a glance: stocks gapping down premarket
Seeking Alpha • 6:08am
Biggest stock movers Wednesday: SYRE, INTU, SAP and more
Seeking Alpha • 4:20am
Aug 25, 2026
Spyre drops on disappointing phase 2 data for rheumatoid arthritis asset
Seeking Alpha • 4:01pm
- 1
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