CDNA (CareDx) Cyclically Adjusted Book per Share: $5.59 (As of Jun. 2026)

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CDNA CareDx Inc CDNA
67 GF Score
Price $46.69
GF Value $25.23
Valuation Significantly Overvalued
! 7 Warning Signs
View Full Analysis

What is CareDx Cyclically Adjusted Book per Share?

CareDx CDNA +4.20% 67 Cyclically Adjusted Book per Share is $5.59 as of Jun. 2026. GuruFocus rates CDNA with a GF Score™ of 67/100 and a GF Value™ of $25.23 (Significantly Overvalued). The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

CareDx's adjusted book value per share for the three months ended in Jun. 2026 was $8.267. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $5.59 for the trailing ten years ended in Jun. 2026.

During the past 12 months, CareDx's average Cyclically Adjusted Book Growth Rate was 10.70% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was 29.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of CareDx was 29.30% per year. The lowest was 29.30% per year. And the median was 29.30% per year.

As of today (2026-08-09), CareDx's current stock price is $46.69. CareDx's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $5.59. CareDx's Cyclically Adjusted PB Ratio of today is 8.35.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of CareDx was 11.72. The lowest was 1.74. And the median was 3.73.


CareDx  (NAS:CDNA) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

CareDx's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=46.69/5.59
=8.35

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of CareDx was 11.72. The lowest was 1.74. And the median was 3.73.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


CareDx Cyclically Adjusted Book per Share Related Terms


CareDx Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for CareDx's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CareDx Cyclically Adjusted Book per Share Chart

CareDx Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 2.40 3.46 4.84 5.19

CareDx Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 5.05 5.14 5.19 5.38 5.59

CDNA vs NEO, WGS, PSNL: Cyclically Adjusted Book per Share Comparison

For the Diagnostics & Research subindustry, CareDx's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CareDx Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, CareDx's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where CareDx's Cyclically Adjusted PB Ratio falls into.


CDNA
67GF Score
CareDx Inc CDNA
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

CareDx Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, CareDx's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=8.267/333.9520*333.9520
=8.267

Current CPI (Jun. 2026) = 333.9520.

CareDx Quarterly Data

Book Value per Share CPI Adj_Book
201609 1.706 241.428 2.360
201612 0.916 241.432 1.267
201703 0.685 243.801 0.938
201706 0.552 244.955 0.753
201709 -0.014 246.819 -0.019
201712 -0.213 246.524 -0.289
201803 0.948 249.554 1.269
201806 0.805 251.989 1.067
201809 1.144 252.439 1.513
201812 2.318 251.233 3.081
201903 2.281 254.202 2.997
201906 2.202 256.143 2.871
201909 2.299 256.759 2.990
201912 2.330 256.974 3.028
202003 2.357 258.115 3.050
202006 5.337 257.797 6.914
202009 5.468 260.280 7.016
202012 5.616 260.474 7.200
202103 9.079 264.877 11.447
202106 9.131 271.696 11.223
202109 8.946 274.310 10.891
202112 8.803 278.802 10.544
202203 8.619 287.504 10.011
202206 8.318 296.311 9.375
202209 8.159 296.808 9.180
202212 8.049 296.797 9.057
202303 7.828 301.836 8.661
202306 7.502 305.109 8.211
202309 7.278 307.789 7.897
202312 5.074 306.746 5.524
202403 4.948 312.332 5.291
202406 5.030 314.175 5.347
202409 5.145 315.301 5.449
202412 6.909 315.605 7.311
202503 6.840 319.799 7.143
202506 6.151 322.561 6.368
202509 6.052 324.800 6.223
202512 5.953 324.054 6.135
202603 6.115 330.213 6.184
202606 8.267 333.952 8.267

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $5.59 mean?
CareDx (CDNA) has a Cyclically Adjusted Book per Share of $5.59 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on CareDx and its competitors.
Is CareDx's Cyclically Adjusted Book per Share too high?
CareDx's current Cyclically Adjusted Book per Share is $5.59. Overall, CareDx has a GF Score™ of 67/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CareDx's Cyclically Adjusted Book per Share compare to NEO and WGS?
CareDx's Cyclically Adjusted Book per Share of $5.59 can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Medical Diagnostics & Research company?
A good Cyclically Adjusted Book per Share depends on the Medical Diagnostics & Research industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on CareDx and its competitors. CareDx's current Cyclically Adjusted Book per Share is $5.59. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CareDx stock overvalued right now?
Based on GuruFocus' analysis, CareDx (CDNA) is currently considered Significantly Overvalued. The stock's GF Value™ is $25.23, compared to a current price of $46.69 — trading 85.1% above its estimated fair value. The current Cyclically Adjusted Book per Share is $5.59. CareDx's overall GF Score™ is 67/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For CareDx (CDNA), the current Cyclically Adjusted Book per Share is $5.59 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CareDx (CDNA) Overvalued in 2026?

Based on GuruFocus' analysis, CareDx stock appears to be overvalued. The current stock price of $46.69 is trading 85.1% above its estimated GF Value™ of $25.23. GuruFocus considers CareDx to be Significantly Overvalued.

Key valuation signals for CDNA:

  • Cyclically Adjusted Book per Share: $5.59
  • GF Value™: $25.23 vs. price of $46.69 (85.1% above fair value)
  • GF Score™: 67/100 with 7 warning signs

No single metric tells the full story. See the CDNA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CareDx Business Description

Other Exchanges 1K9:Germany
Address 8000 Marina Boulevard, Brisbane, CA, USA, 94005
CareDx Inc operates as a precision medicine company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. It offers testing services, products, and digital solutions along with the pre- and post-transplant patient journey and is a provider of genomics-based information for transplant patients. The Company's commercially available testing services consist of AlloSure Kidney, AlloMap Heart, AlloSure Heart, a dd-cfDNA solution for heart transplant patients, and AlloSure Lung, a dd-cfDNA solution for lung transplant patients. Geographically it generates the majority of its revenue from the United States. The company generates the majority of revenue from the Testing services.
67GF Score

Get the complete analysis for CDNA

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$46.69
Price
$25.23
GF Value