LXRX (Lexicon Pharmaceuticals) Cyclically Adjusted Book per Share: $0.78 (As of Mar. 2026)

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LXRX Lexicon Pharmaceuticals Inc LXRX
39 GF Score
Price $2.31
! 5 Warning Signs
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What is Lexicon Pharmaceuticals Cyclically Adjusted Book per Share?

Lexicon Pharmaceuticals LXRX -1.28% 39 Cyclically Adjusted Book per Share is $0.78 as of Mar. 2026. GuruFocus rates LXRX with a GF Score™ of 39/100. The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Lexicon Pharmaceuticals's adjusted book value per share for the three months ended in Mar. 2026 was $0.479. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $0.78 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Lexicon Pharmaceuticals's average Cyclically Adjusted Book Growth Rate was -24.30% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was -17.40% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was -16.20% per year. During the past 10 years, the average Cyclically Adjusted Book Growth Rate was -18.40% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Lexicon Pharmaceuticals was -13.20% per year. The lowest was -23.40% per year. And the median was -17.45% per year.

As of today (2026-07-31), Lexicon Pharmaceuticals's current stock price is $2.31. Lexicon Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $0.78. Lexicon Pharmaceuticals's Cyclically Adjusted PB Ratio of today is 2.96.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Lexicon Pharmaceuticals was 4.13. The lowest was 0.33. And the median was 1.64.


Lexicon Pharmaceuticals  (NAS:LXRX) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Lexicon Pharmaceuticals's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=2.31/0.78
=2.96

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Lexicon Pharmaceuticals was 4.13. The lowest was 0.33. And the median was 1.64.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Lexicon Pharmaceuticals Cyclically Adjusted Book per Share Related Terms


Lexicon Pharmaceuticals Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Lexicon Pharmaceuticals's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lexicon Pharmaceuticals Cyclically Adjusted Book per Share Chart

Lexicon Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1.79 1.49 1.23 1.09 0.84

Lexicon Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.03 0.97 0.92 0.84 0.78

LXRX vs EYPT, OLMA, LBRX: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Lexicon Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lexicon Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lexicon Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Lexicon Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


LXRX
39GF Score
Lexicon Pharmaceuticals Inc LXRX
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Lexicon Pharmaceuticals Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Lexicon Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.479/330.2130*330.2130
=0.479

Current CPI (Mar. 2026) = 330.2130.

Lexicon Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201606 2.093 241.018 2.868
201609 1.780 241.428 2.435
201612 1.509 241.432 2.064
201703 1.279 243.801 1.732
201706 1.007 244.955 1.357
201709 0.742 246.819 0.993
201712 0.647 246.524 0.867
201803 0.248 249.554 0.328
201806 -0.048 251.989 -0.063
201809 -0.278 252.439 -0.364
201812 -0.249 251.233 -0.327
201903 -0.430 254.202 -0.559
201906 -0.611 256.143 -0.788
201909 1.550 256.759 1.993
201912 1.102 256.974 1.416
202003 0.512 258.115 0.655
202006 -0.100 257.797 -0.128
202009 0.753 260.280 0.955
202012 1.105 260.474 1.401
202103 1.057 264.877 1.318
202106 0.950 271.696 1.155
202109 0.918 274.310 1.105
202112 0.763 278.802 0.904
202203 0.620 287.504 0.712
202206 0.473 296.311 0.527
202209 0.763 296.808 0.849
202212 0.621 296.797 0.691
202303 0.464 301.836 0.508
202306 0.761 305.109 0.824
202309 0.570 307.789 0.612
202312 0.380 306.746 0.409
202403 1.173 312.332 1.240
202406 0.664 314.175 0.698
202409 0.494 315.301 0.517
202412 0.404 315.605 0.423
202503 0.339 319.799 0.350
202506 0.356 322.561 0.364
202509 0.331 324.800 0.337
202512 0.296 324.054 0.302
202603 0.479 330.213 0.479

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $0.78 mean?
Lexicon Pharmaceuticals (LXRX) has a Cyclically Adjusted Book per Share of $0.78 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Lexicon Pharmaceuticals and its competitors.
Is Lexicon Pharmaceuticals' Cyclically Adjusted Book per Share too high?
Lexicon Pharmaceuticals' current Cyclically Adjusted Book per Share is $0.78. Overall, Lexicon Pharmaceuticals has a GF Score™ of 39/100, reflecting its overall financial health beyond just this single metric.
How does Lexicon Pharmaceuticals' Cyclically Adjusted Book per Share compare to EYPT and OLMA?
Lexicon Pharmaceuticals' Cyclically Adjusted Book per Share of $0.78 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Lexicon Pharmaceuticals and its competitors. Lexicon Pharmaceuticals's current Cyclically Adjusted Book per Share is $0.78. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lexicon Pharmaceuticals stock overvalued right now?
Lexicon Pharmaceuticals (LXRX) has a current Cyclically Adjusted Book per Share of $0.78. The current Cyclically Adjusted Book per Share is $0.78. Lexicon Pharmaceuticals' overall GF Score™ is 39/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Lexicon Pharmaceuticals (LXRX), the current Cyclically Adjusted Book per Share is $0.78 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Lexicon Pharmaceuticals Business Description

Address 2445 Technology Forest Boulevard, 11th Floor, The Woodlands, TX, USA, 77381
Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, and LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.
39GF Score

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Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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