MCRB (Seres Therapeutics) Cyclically Adjusted Book per Share: $13.39 (As of Jun. 2026)

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MCRB Seres Therapeutics Inc MCRB
13 GF Score
Price $4.76
! 5 Warning Signs
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What is Seres Therapeutics Cyclically Adjusted Book per Share?

Seres Therapeutics MCRB -4.80% 13 Cyclically Adjusted Book per Share is $13.39 as of Jun. 2026. GuruFocus rates MCRB with a GF Score™ of 13/100. The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Seres Therapeutics's adjusted book value per share for the three months ended in Jun. 2026 was $3.514. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $13.39 for the trailing ten years ended in Jun. 2026.

During the past 12 months, Seres Therapeutics's average Cyclically Adjusted Book Growth Rate was -48.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-08-27), Seres Therapeutics's current stock price is $4.76. Seres Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $13.39. Seres Therapeutics's Cyclically Adjusted PB Ratio of today is 0.36.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Seres Therapeutics was 1.28. The lowest was 0.23. And the median was 0.55.


Seres Therapeutics  (NAS:MCRB) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Seres Therapeutics's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=4.76/13.39
=0.36

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Seres Therapeutics was 1.28. The lowest was 0.23. And the median was 0.55.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Seres Therapeutics Cyclically Adjusted Book per Share Related Terms


Seres Therapeutics Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Seres Therapeutics's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Seres Therapeutics Cyclically Adjusted Book per Share Chart

Seres Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 30.60 29.23 18.95

Seres Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 26.07 22.49 18.95 16.03 13.39

MCRB vs IBO, TIL, ATYR: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Seres Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Seres Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Seres Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Seres Therapeutics's Cyclically Adjusted PB Ratio falls into.


MCRB
13GF Score
Seres Therapeutics Inc MCRB
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Seres Therapeutics Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Seres Therapeutics's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=3.514/333.9520*333.9520
=3.514

Current CPI (Jun. 2026) = 333.9520.

Seres Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201609 76.312 241.428 105.558
201612 65.724 241.432 90.910
201703 55.202 243.801 75.614
201706 43.508 244.955 59.315
201709 42.207 246.819 57.107
201712 29.916 246.524 40.525
201803 4.935 249.554 6.604
201806 -6.504 251.989 -8.620
201809 -14.968 252.439 -19.801
201812 -23.471 251.233 -31.199
201903 -33.982 254.202 -44.643
201906 -5.140 256.143 -6.701
201909 -9.205 256.759 -11.972
201912 -13.779 256.974 -17.907
202003 -17.201 258.115 -22.255
202006 -17.454 257.797 -22.610
202009 41.230 260.280 52.900
202012 38.213 260.474 48.993
202103 31.383 264.877 39.567
202106 22.038 271.696 27.088
202109 38.270 274.310 46.591
202112 28.626 278.802 34.289
202203 17.557 287.504 20.393
202206 4.996 296.311 5.631
202209 10.864 296.808 12.224
202212 1.722 296.797 1.938
202303 -7.563 301.836 -8.368
202306 3.532 305.109 3.866
202309 -2.351 307.789 -2.551
202312 -6.643 306.746 -7.232
202403 -7.889 312.332 -8.435
202406 -11.484 314.175 -12.207
202409 2.811 315.301 2.977
202412 1.594 315.605 1.687
202503 5.779 319.799 6.035
202506 3.764 322.561 3.897
202509 4.985 324.800 5.125
202512 4.627 324.054 4.768
202603 2.763 330.213 2.794
202606 3.514 333.952 3.514

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $13.39 mean?
Seres Therapeutics (MCRB) has a Cyclically Adjusted Book per Share of $13.39 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Seres Therapeutics and its competitors.
Is Seres Therapeutics' Cyclically Adjusted Book per Share too high?
Seres Therapeutics' current Cyclically Adjusted Book per Share is $13.39. Overall, Seres Therapeutics has a GF Score™ of 13/100, reflecting its overall financial health beyond just this single metric.
How does Seres Therapeutics' Cyclically Adjusted Book per Share compare to IBO and TIL?
Seres Therapeutics' Cyclically Adjusted Book per Share of $13.39 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Seres Therapeutics and its competitors. Seres Therapeutics's current Cyclically Adjusted Book per Share is $13.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Seres Therapeutics stock overvalued right now?
Seres Therapeutics (MCRB) has a current Cyclically Adjusted Book per Share of $13.39. The current Cyclically Adjusted Book per Share is $13.39. Seres Therapeutics' overall GF Score™ is 13/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Seres Therapeutics (MCRB), the current Cyclically Adjusted Book per Share is $13.39 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Seres Therapeutics Business Description

Other Exchanges 1S90:Germany
Address 101 Cambridgepark Drive, Cambridge, MA, USA, 02140
Seres Therapeutics Inc is a clinical-stage biotechnology company focused on the development of live biotherapeutic candidates. Its pipeline includes candidates such as SER-155 and SER-603, aimed at preventing and treating bacterial infections, antimicrobial resistance, and gastrointestinal immune diseases. The company operates as a single reportable segment, mainly developing microbiome-based therapies targeting bacterial infections, antimicrobial resistance, and gastrointestinal immune diseases.
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Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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