PBYI (Puma Biotechnology) Cyclically Adjusted Book per Share: $1.65 (As of Mar. 2026)

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PBYI Puma Biotechnology Inc PBYI
53 GF Score
Price $7.69
GF Value $3.34
Valuation Significantly Overvalued
! 9 Warning Signs
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What is Puma Biotechnology Cyclically Adjusted Book per Share?

Puma Biotechnology PBYI -3.03% 53 Cyclically Adjusted Book per Share is $1.65 as of Mar. 2026. GuruFocus rates PBYI with a GF Score™ of 53/100 and a GF Value™ of $3.34 (Significantly Overvalued). The stock has 9 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Puma Biotechnology's adjusted book value per share for the three months ended in Mar. 2026 was $2.524. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $1.65 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Puma Biotechnology's average Cyclically Adjusted Book Growth Rate was -27.90% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was -19.10% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was -11.40% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Puma Biotechnology was -4.10% per year. The lowest was -19.10% per year. And the median was -7.60% per year.

As of today (2026-08-04), Puma Biotechnology's current stock price is $7.69. Puma Biotechnology's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $1.65. Puma Biotechnology's Cyclically Adjusted PB Ratio of today is 4.66.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Puma Biotechnology was 22.35. The lowest was 0.55. And the median was 2.24.


Puma Biotechnology  (NAS:PBYI) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Puma Biotechnology's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=7.69/1.65
=4.66

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Puma Biotechnology was 22.35. The lowest was 0.55. And the median was 2.24.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Puma Biotechnology Cyclically Adjusted Book per Share Related Terms


Puma Biotechnology Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Puma Biotechnology's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Puma Biotechnology Cyclically Adjusted Book per Share Chart

Puma Biotechnology Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.29 3.27 2.99 2.53 1.73

Puma Biotechnology Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.29 2.07 1.88 1.73 1.65

PBYI vs EVMN, OCGN, EDIT: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Puma Biotechnology's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Puma Biotechnology Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Puma Biotechnology's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Puma Biotechnology's Cyclically Adjusted PB Ratio falls into.


PBYI
53GF Score
Puma Biotechnology Inc PBYI
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Puma Biotechnology Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Puma Biotechnology's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=2.524/330.2130*330.2130
=2.524

Current CPI (Mar. 2026) = 330.2130.

Puma Biotechnology Quarterly Data

Book Value per Share CPI Adj_Book
201606 3.911 241.018 5.358
201609 2.804 241.428 3.835
201612 5.698 241.432 7.793
201703 4.529 243.801 6.134
201706 3.241 244.955 4.369
201709 2.118 246.819 2.834
201712 1.418 246.524 1.899
201803 1.521 249.554 2.013
201806 1.011 251.989 1.325
201809 1.204 252.439 1.575
201812 0.895 251.233 1.176
201903 1.127 254.202 1.464
201906 0.562 256.143 0.725
201909 0.441 256.759 0.567
201912 0.445 256.974 0.572
202003 0.238 258.115 0.304
202006 0.591 257.797 0.757
202009 -0.011 260.280 -0.014
202012 -0.148 260.474 -0.188
202103 0.408 264.877 0.509
202106 0.723 271.696 0.879
202109 -0.267 274.310 -0.321
202112 -0.059 278.802 -0.070
202203 0.159 287.504 0.183
202206 0.436 296.311 0.486
202209 0.486 296.808 0.541
202212 0.466 296.797 0.518
202303 0.554 301.836 0.606
202306 0.648 305.109 0.701
202309 0.815 307.789 0.874
202312 1.122 306.746 1.208
202403 1.057 312.332 1.118
202406 1.001 314.175 1.052
202409 1.449 315.301 1.518
202412 1.876 315.605 1.963
202503 1.957 319.799 2.021
202506 2.099 322.561 2.149
202509 2.288 324.800 2.326
202512 2.586 324.054 2.635
202603 2.524 330.213 2.524

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $1.65 mean?
Puma Biotechnology (PBYI) has a Cyclically Adjusted Book per Share of $1.65 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Puma Biotechnology and its competitors.
Is Puma Biotechnology's Cyclically Adjusted Book per Share too high?
Puma Biotechnology's current Cyclically Adjusted Book per Share is $1.65. Overall, Puma Biotechnology has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Puma Biotechnology's Cyclically Adjusted Book per Share compare to EVMN and OCGN?
Puma Biotechnology's Cyclically Adjusted Book per Share of $1.65 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Puma Biotechnology and its competitors. Puma Biotechnology's current Cyclically Adjusted Book per Share is $1.65. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Puma Biotechnology stock overvalued right now?
Based on GuruFocus' analysis, Puma Biotechnology (PBYI) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.34, compared to a current price of $7.69 — trading 130.2% above its estimated fair value. The current Cyclically Adjusted Book per Share is $1.65. Puma Biotechnology's overall GF Score™ is 53/100 with 9 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Puma Biotechnology (PBYI), the current Cyclically Adjusted Book per Share is $1.65 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Puma Biotechnology (PBYI) Overvalued in 2026?

Based on GuruFocus' analysis, Puma Biotechnology stock appears to be overvalued. The current stock price of $7.69 is trading 130.2% above its estimated GF Value™ of $3.34. GuruFocus considers Puma Biotechnology to be Significantly Overvalued.

Key valuation signals for PBYI:

  • Cyclically Adjusted Book per Share: $1.65
  • GF Value™: $3.34 vs. price of $7.69 (130.2% above fair value)
  • GF Score™: 53/100 with 9 warning signs

No single metric tells the full story. See the PBYI stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Puma Biotechnology Business Description

Address 10880 Wilshire Boulevard, Suite 1700, Los Angeles, CA, USA, 90024
Puma Biotechnology Inc is a biopharmaceutical company that develops and commercializes inventive products to enhance cancer care and improve treatment outcomes for patients. It is currently commercializing NERLYNX, an oral version of neratinib, for the treatment of HER2-positive breast cancer. Also, it is developing Alisertib, a selective, small-molecule inhibitor of aurora kinase A that is designed to disrupt mitosis, resulting in apoptosis of rapidly proliferating tumor cells that are dependent on aurora kinase A.
53GF Score

Get the complete analysis for PBYI

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.69
Price
$3.34
GF Value