Illumina (STU:ILU) Cyclically Adjusted Book per Share: €32.46 (As of Jun. 2026)

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STU:ILU Illumina Inc STU:ILU
72 GF Score
Price €179.12
GF Value €116.76
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Illumina Cyclically Adjusted Book per Share?

Illumina STU:ILU -0.56% 72 Cyclically Adjusted Book per Share is €32.46 as of Jun. 2026. GuruFocus rates STU:ILU with a GF Score™ of 72/100 and a GF Value™ of €116.76 (Significantly Overvalued). The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Illumina's adjusted book value per share for the three months ended in Jun. 2026 was €16.439. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €32.46 for the trailing ten years ended in Jun. 2026.

During the past 12 months, Illumina's average Cyclically Adjusted Book Growth Rate was 3.30% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was 6.20% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was 14.00% per year. During the past 10 years, the average Cyclically Adjusted Book Growth Rate was 17.20% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Illumina was 24.80% per year. The lowest was 6.20% per year. And the median was 17.60% per year.

As of today (2026-09-16), Illumina's current stock price is €179.12. Illumina's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was €32.46. Illumina's Cyclically Adjusted PB Ratio of today is 5.52.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Illumina was 28.82. The lowest was 2.06. And the median was 15.85.


Illumina  (STU:ILU) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Illumina's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=179.12/32.455
=5.52

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Illumina was 28.82. The lowest was 2.06. And the median was 15.85.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Illumina Cyclically Adjusted Book per Share Related Terms


Illumina Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Illumina's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Illumina Cyclically Adjusted Book per Share Chart

Illumina Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 22.49 26.81 29.84 31.01 31.73

Illumina Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 31.56 31.69 31.60 32.14 32.46

STU:ILU vs MTD, LH, DGX: Cyclically Adjusted Book per Share Comparison

For the Diagnostics & Research subindustry, Illumina's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Illumina Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Illumina's Cyclically Adjusted PB Ratio falls into.


STU:ILU
72GF Score
Illumina Inc STU:ILU
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Illumina Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Illumina's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=16.439/333.9520*333.9520
=16.439

Current CPI (Jun. 2026) = 333.9520.

Illumina Quarterly Data

Book Value per Share CPI Adj_Book
201609 14.259 241.428 19.724
201612 15.008 241.432 20.759
201703 16.714 243.801 22.894
201706 16.785 244.955 22.883
201709 17.259 246.819 23.352
201712 16.820 246.524 22.785
201803 18.187 249.554 24.338
201806 20.789 251.989 27.551
201809 22.326 252.439 29.535
201812 23.244 251.233 30.897
201903 24.882 254.202 32.688
201906 25.703 256.143 33.511
201909 27.699 256.759 36.027
201912 27.956 256.974 36.330
202003 28.736 258.115 37.179
202006 27.827 257.797 36.047
202009 27.452 260.280 35.222
202012 26.277 260.474 33.690
202103 28.684 264.877 36.164
202106 29.714 271.696 36.523
202109 58.218 274.310 70.876
202112 60.154 278.802 72.053
202203 62.369 287.504 72.445
202206 63.630 296.311 71.713
202209 43.763 296.808 49.240
202212 39.134 296.797 44.033
202303 38.990 301.836 43.139
202306 38.027 305.109 41.622
202309 35.258 307.789 38.255
202312 32.709 306.746 35.610
202403 33.392 312.332 35.703
202406 8.427 314.175 8.957
202409 12.051 315.301 12.764
202412 14.413 315.605 15.251
202503 13.787 319.799 14.397
202506 12.491 322.561 12.932
202509 13.244 324.800 13.617
202512 15.154 324.054 15.617
202603 15.280 330.213 15.453
202606 16.439 333.952 16.439

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of €32.46 mean?
Illumina (STU:ILU) has a Cyclically Adjusted Book per Share of €32.46 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Illumina and its competitors.
Is Illumina's Cyclically Adjusted Book per Share too high?
Illumina's current Cyclically Adjusted Book per Share is €32.46. Overall, Illumina has a GF Score™ of 72/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Illumina's Cyclically Adjusted Book per Share compare to MTD and LH?
Illumina's Cyclically Adjusted Book per Share of €32.46 can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Medical Diagnostics & Research company?
A good Cyclically Adjusted Book per Share depends on the Medical Diagnostics & Research industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Illumina and its competitors. Illumina's current Cyclically Adjusted Book per Share is €32.46. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Based on GuruFocus' analysis, Illumina (STU:ILU) is currently considered Significantly Overvalued. The stock's GF Value™ is €116.76, compared to a current price of €179.12 — trading 53.4% above its estimated fair value. The current Cyclically Adjusted Book per Share is €32.46. Illumina's overall GF Score™ is 72/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Illumina (STU:ILU), the current Cyclically Adjusted Book per Share is €32.46 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Illumina (STU:ILU) Overvalued in 2026?

Based on GuruFocus' analysis, Illumina stock appears to be overvalued. The current stock price of €179.12 is trading 53.4% above its estimated GF Value™ of €116.76. GuruFocus considers Illumina to be Significantly Overvalued.

Key valuation signals for STU:ILU:

  • Cyclically Adjusted Book per Share: €32.46
  • GF Value™: €116.76 vs. price of €179.12 (53.4% above fair value)
  • GF Score™: 72/100 with 7 warning signs

No single metric tells the full story. See the STU:ILU stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Illumina Business Description

Address 5200 Illumina Way, San Diego, CA, USA, 92122
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
72GF Score

Get the complete analysis for STU:ILU

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€179.12
Price
€116.76
GF Value