SYRS (Syros Pharmaceuticals) Cyclically Adjusted Book per Share: $17.72 (As of Sep. 2024)


SYRS Syros Pharmaceuticals Inc SYRS
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What is Syros Pharmaceuticals Cyclically Adjusted Book per Share?

Syros Pharmaceuticals SYRS 12 Cyclically Adjusted Book per Share is $17.72 as of Sep. 2024. GuruFocus rates SYRS with a GF Score™ of 12/100.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Syros Pharmaceuticals's adjusted book value per share for the three months ended in Sep. 2024 was $-0.415. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $17.72 for the trailing ten years ended in Sep. 2024.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-07-02), Syros Pharmaceuticals's current stock price is $0.0001. Syros Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Sep. 2024 was $17.72. Syros Pharmaceuticals's Cyclically Adjusted PB Ratio of today is 0.00.


Syros Pharmaceuticals  (OTCPK:SYRS) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Syros Pharmaceuticals's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=0.0001/17.72
=0.00

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Syros Pharmaceuticals Cyclically Adjusted Book per Share Related Terms


Syros Pharmaceuticals Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Syros Pharmaceuticals's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Syros Pharmaceuticals Cyclically Adjusted Book per Share Chart

Syros Pharmaceuticals Annual Data
Trend Dec14 Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

Syros Pharmaceuticals Quarterly Data
Dec19 Mar20 Jun20 Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 17.72

SYRS vs AFMDQ, BTAX, TRVN: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Syros Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Syros Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Syros Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Syros Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


SYRS
12GF Score
Syros Pharmaceuticals Inc SYRS
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Syros Pharmaceuticals Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Syros Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Sep. 2024 was:

Adj_Book= Book Value per Share /CPI of Sep. 2024 (Change)*Current CPI (Sep. 2024)
=-0.415/315.3010*315.3010
=-0.415

Current CPI (Sep. 2024) = 315.3010.

Syros Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201412 -9.566 234.812 -12.845
201503 0.000 236.119 0.000
201506 0.000 238.638 0.000
201509 0.000 237.945 0.000
201512 -21.074 236.525 -28.093
201603 28.083 238.132 37.184
201606 -30.058 241.018 -39.322
201609 38.845 241.428 50.731
201612 34.475 241.432 45.023
201703 29.922 243.801 38.697
201706 34.724 244.955 44.696
201709 29.894 246.819 38.188
201712 24.725 246.524 31.623
201803 32.413 249.554 40.952
201806 32.336 251.989 40.460
201809 28.183 252.439 35.201
201812 23.271 251.233 29.205
201903 18.957 254.202 23.513
201906 26.370 256.143 32.460
201909 22.284 256.759 27.365
201912 18.258 256.974 22.402
202003 16.753 258.115 20.465
202006 13.638 257.797 16.680
202009 10.028 260.280 12.148
202012 16.107 260.474 19.497
202103 24.233 264.877 28.846
202106 20.991 271.696 24.360
202109 17.123 274.310 19.682
202112 13.740 278.802 15.539
202203 9.991 287.504 10.957
202206 4.924 296.311 5.240
202209 6.387 296.808 6.785
202212 6.304 296.797 6.697
202303 5.231 301.836 5.464
202306 3.537 305.109 3.655
202309 1.752 307.789 1.795
202312 0.630 306.746 0.648
202403 0.563 312.332 0.568
202406 -0.237 314.175 -0.238
202409 -0.415 315.301 -0.415

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $17.72 mean?
Syros Pharmaceuticals (SYRS) has a Cyclically Adjusted Book per Share of $17.72 as of Sep. 2024. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Syros Pharmaceuticals and its competitors.
Is Syros Pharmaceuticals' Cyclically Adjusted Book per Share too high?
Syros Pharmaceuticals' current Cyclically Adjusted Book per Share is $17.72. Overall, Syros Pharmaceuticals has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Syros Pharmaceuticals' Cyclically Adjusted Book per Share compare to AFMDQ and BTAX?
Syros Pharmaceuticals' Cyclically Adjusted Book per Share of $17.72 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Syros Pharmaceuticals and its competitors. Syros Pharmaceuticals's current Cyclically Adjusted Book per Share is $17.72. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Syros Pharmaceuticals stock overvalued right now?
Syros Pharmaceuticals (SYRS) has a current Cyclically Adjusted Book per Share of $17.72. The current Cyclically Adjusted Book per Share is $17.72. Syros Pharmaceuticals' overall GF Score™ is 12/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Syros Pharmaceuticals (SYRS), the current Cyclically Adjusted Book per Share is $17.72 as of Sep. 2024. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Syros Pharmaceuticals Business Description

Address 35 CambridgePark Drive, 4th Floor, Cambridge, MA, USA, 02140
Syros Pharmaceuticals Inc is a biopharmaceutical company committed to developing new standards of care for the frontline treatment of patients with hematologic malignancies.
12GF Score

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Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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