Healios KK (TSE:4593) Cyclically Adjusted Book per Share: 円160.61 (As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TSE:4593 Healios KK TSE:4593
51 GF Score
Price 円267.00
GF Value 円43.61
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is Healios KK Cyclically Adjusted Book per Share?

Healios KK TSE:4593 -1.11% 51 Cyclically Adjusted Book per Share is 円160.61 as of Jun. 2026. GuruFocus rates TSE:4593 with a GF Score™ of 51/100 and a GF Value™ of 円43.61 (Significantly Overvalued). The stock has 6 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Healios KK's adjusted book value per share for the three months ended in Jun. 2026 was 円55.903. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is 円160.61 for the trailing ten years ended in Jun. 2026.

During the past 12 months, Healios KK's average Cyclically Adjusted Book Growth Rate was -9.10% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-08-25), Healios KK's current stock price is 円267.00. Healios KK's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was 円160.61. Healios KK's Cyclically Adjusted PB Ratio of today is 1.66.

During the past 12 years, the highest Cyclically Adjusted PB Ratio of Healios KK was 3.96. The lowest was 0.93. And the median was 1.87.


Healios KK  (TSE:4593) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Healios KK's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=267.00/160.61
=1.66

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 12 years, the highest Cyclically Adjusted PB Ratio of Healios KK was 3.96. The lowest was 0.93. And the median was 1.87.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Healios KK Cyclically Adjusted Book per Share Related Terms


Healios KK Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Healios KK's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Healios KK Cyclically Adjusted Book per Share Chart

Healios KK Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 185.27 166.89

Healios KK Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 176.66 170.95 166.89 162.71 160.61

TSE:4593 vs VRTX, REGN, RVMD: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Healios KK's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Healios KK Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Healios KK's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Healios KK's Cyclically Adjusted PB Ratio falls into.


TSE:4593
51GF Score
Healios KK TSE:4593
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Healios KK Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Healios KK's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book= Book Value per Share /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=55.903/113.6000*113.6000
=55.903

Current CPI (Jun. 2026) = 113.6000.

Healios KK Quarterly Data

Book Value per Share CPI Adj_Book
201609 154.437 98.000 179.021
201612 146.499 98.400 169.129
201703 179.210 98.100 207.526
201706 287.636 98.500 331.730
201709 285.252 98.800 327.982
201712 329.105 99.400 376.120
201803 318.376 99.200 364.592
201806 266.893 99.200 305.636
201809 255.523 99.900 290.565
201812 291.685 99.700 332.351
201903 202.589 99.700 230.834
201906 185.983 99.800 211.700
201909 201.397 100.100 228.558
201912 240.589 100.500 271.949
202003 260.039 100.300 294.521
202006 228.374 99.900 259.693
202009 184.153 99.900 209.407
202012 151.821 99.300 173.684
202103 137.711 99.900 156.596
202106 110.074 99.500 125.672
202109 191.315 100.100 217.117
202112 156.651 100.100 177.778
202203 122.978 101.100 138.183
202206 80.891 101.800 90.267
202209 77.684 103.100 85.596
202212 69.331 104.100 75.658
202303 60.530 104.400 65.864
202306 50.955 105.200 55.024
202309 75.111 106.200 80.345
202312 51.729 106.800 55.023
202403 41.052 107.200 43.503
202406 35.992 108.200 37.788
202409 18.995 108.900 19.815
202412 22.867 110.700 23.466
202503 19.268 111.100 19.702
202506 11.467 111.700 11.662
202509 25.430 112.000 25.793
202512 42.255 113.000 42.479
202603 55.903 112.700 56.349
202606 55.903 113.600 55.903

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of 円160.61 mean?
Healios KK (TSE:4593) has a Cyclically Adjusted Book per Share of 円160.61 as of Jun. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Healios KK and its competitors.
Is Healios KK's Cyclically Adjusted Book per Share too high?
Healios KK's current Cyclically Adjusted Book per Share is 円160.61. Overall, Healios KK has a GF Score™ of 51/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Healios KK's Cyclically Adjusted Book per Share compare to VRTX and REGN?
Healios KK's Cyclically Adjusted Book per Share of 円160.61 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Healios KK and its competitors. Healios KK's current Cyclically Adjusted Book per Share is 円160.61. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Healios KK stock overvalued right now?
Based on GuruFocus' analysis, Healios KK (TSE:4593) is currently considered Significantly Overvalued. The stock's GF Value™ is 円43.61, compared to a current price of 円267.00 — trading 512.2% above its estimated fair value. The current Cyclically Adjusted Book per Share is 円160.61. Healios KK's overall GF Score™ is 51/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Healios KK (TSE:4593), the current Cyclically Adjusted Book per Share is 円160.61 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Healios KK (TSE:4593) Overvalued in 2026?

Based on GuruFocus' analysis, Healios KK stock appears to be overvalued. The current stock price of 円267.00 is trading 512.2% above its estimated GF Value™ of 円43.61. GuruFocus considers Healios KK to be Significantly Overvalued.

Key valuation signals for TSE:4593:

  • Cyclically Adjusted Book per Share: 円160.61
  • GF Value™: 円43.61 vs. price of 円267.00 (512.2% above fair value)
  • GF Score™: 51/100 with 6 warning signs

No single metric tells the full story. See the TSE:4593 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Healios KK Business Description

Other Exchanges HLOSF:USA6VX:Germany
Address 1-1-2 Yurakucho, Hibiya Mitsui Tower 12Floor, Work Styling, Chiyoda-ku, Tokyo, JPN, 100-0006
Healios KK is involved in development and sales of opthalmological surgery adjuvants and research, development and manufacture of cell therapy products and regenerative medicine products. The company is developing treatments for age-related macular degeneration and organ anlage transplantation therapy. The company develops next-generation cell therapies using a proprietary gene-edited induced pluripotent stem cell (iPSC) platform, with programs targeting immuno-oncology, ophthalmology, liver diseases, ischemic stroke, and acute respiratory distress syndrome.
51GF Score

Get the complete analysis for TSE:4593

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円267.00
Price
円43.61
GF Value