XENE (Xenon Pharmaceuticals) Cyclically Adjusted Book per Share: $5.96 (As of Mar. 2026)


XENE Xenon Pharmaceuticals Inc XENE
25 GF Score
Price $60.23
! 5 Warning Signs
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What is Xenon Pharmaceuticals Cyclically Adjusted Book per Share?

Xenon Pharmaceuticals XENE +0.16% 25 Cyclically Adjusted Book per Share is $5.96 as of Mar. 2026. GuruFocus rates XENE with a GF Score™ of 25/100. The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Xenon Pharmaceuticals's adjusted book value per share for the three months ended in Mar. 2026 was $13.846. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $5.96 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Xenon Pharmaceuticals's average Cyclically Adjusted Book Growth Rate was 33.00% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-06-30), Xenon Pharmaceuticals's current stock price is $60.225. Xenon Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $5.96. Xenon Pharmaceuticals's Cyclically Adjusted PB Ratio of today is 10.10.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Xenon Pharmaceuticals was 23.70. The lowest was 6.18. And the median was 16.09.


Xenon Pharmaceuticals  (NAS:XENE) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Xenon Pharmaceuticals's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=60.225/5.96
=10.10

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Xenon Pharmaceuticals was 23.70. The lowest was 6.18. And the median was 16.09.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Xenon Pharmaceuticals Cyclically Adjusted Book per Share Related Terms


Xenon Pharmaceuticals Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Xenon Pharmaceuticals's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xenon Pharmaceuticals Cyclically Adjusted Book per Share Chart

Xenon Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 3.02 4.01 5.33

Xenon Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 4.48 4.90 5.28 5.33 5.96

XENE vs DFTX, LEGN, TVTX: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Xenon Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xenon Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xenon Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Xenon Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


XENE
25GF Score
Xenon Pharmaceuticals Inc XENE
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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Xenon Pharmaceuticals Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Xenon Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=13.846/132.2623*132.2623
=13.846

Current CPI (Mar. 2026) = 132.2623.

Xenon Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201606 -6.674 102.002 -8.654
201609 -5.789 101.765 -7.524
201612 3.564 101.449 4.647
201703 -6.481 102.634 -8.352
201706 -6.856 103.029 -8.801
201709 -7.253 103.345 -9.283
201712 1.997 103.345 2.556
201803 0.471 105.004 0.593
201806 1.632 105.557 2.045
201809 3.939 105.636 4.932
201812 3.711 105.399 4.657
201903 3.282 106.979 4.058
201906 2.912 107.690 3.576
201909 2.583 107.611 3.175
201912 2.994 107.769 3.674
202003 5.156 107.927 6.319
202006 5.188 108.401 6.330
202009 4.980 108.164 6.089
202012 4.673 108.559 5.693
202103 6.556 110.298 7.862
202106 6.062 111.720 7.177
202109 5.824 112.905 6.823
202112 10.503 113.774 12.210
202203 10.212 117.646 11.481
202206 12.625 120.806 13.822
202209 12.042 120.648 13.201
202212 11.528 120.964 12.605
202303 10.885 122.702 11.733
202306 10.146 124.203 10.804
202309 9.793 125.230 10.343
202312 12.311 125.072 13.019
202403 11.764 126.258 12.323
202406 11.155 127.522 11.570
202409 10.526 127.285 10.938
202412 9.879 127.364 10.259
202503 9.192 129.181 9.411
202506 8.240 129.892 8.390
202509 7.255 130.287 7.365
202512 7.271 130.366 7.377
202603 13.846 132.262 13.846

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of $5.96 mean?
Xenon Pharmaceuticals (XENE) has a Cyclically Adjusted Book per Share of $5.96 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Xenon Pharmaceuticals and its competitors.
Is Xenon Pharmaceuticals' Cyclically Adjusted Book per Share too high?
Xenon Pharmaceuticals' current Cyclically Adjusted Book per Share is $5.96. Overall, Xenon Pharmaceuticals has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Xenon Pharmaceuticals' Cyclically Adjusted Book per Share compare to DFTX and LEGN?
Xenon Pharmaceuticals' Cyclically Adjusted Book per Share of $5.96 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Xenon Pharmaceuticals and its competitors. Xenon Pharmaceuticals's current Cyclically Adjusted Book per Share is $5.96. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xenon Pharmaceuticals stock overvalued right now?
Xenon Pharmaceuticals (XENE) has a current Cyclically Adjusted Book per Share of $5.96. The current Cyclically Adjusted Book per Share is $5.96. Xenon Pharmaceuticals' overall GF Score™ is 25/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Xenon Pharmaceuticals (XENE), the current Cyclically Adjusted Book per Share is $5.96 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Xenon Pharmaceuticals Business Description

Other Exchanges XP0:Germany
Address 200-3650 Gilmore Way, Burnaby, BC, CAN, V5G 4W8
Xenon Pharmaceuticals Inc is a neuroscience-focused biopharmaceutical company committed to improving the lives of people living with neurological and psychiatric disorders. It is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. The product candidates of the group include XEN1101, NBI-921352, and XEN496 for Epilepsy and Nav1.7 oral inhibitors for Pain.
25GF Score

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Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$60.23
Price