Synlogic (STU:MIN) Cyclically Adjusted FCF per Share: €-251.24 (As of Mar. 2026)


STU:MIN Synlogic Inc STU:MIN
30 GF Score
Price €3.63
GF Value €0.15
! 1 Warning Sign
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What is Synlogic Cyclically Adjusted FCF per Share?

Synlogic STU:MIN 30 Cyclically Adjusted FCF per Share is €-251.24 as of Mar. 2026. GuruFocus rates STU:MIN with a GF Score™ of 30/100 and a GF Value™ of €0.15. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted FCF per Share and the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years.

Synlogic's adjusted free cash flow per share for the three months ended in Mar. 2026 was €-0.039. Add all the adjusted free cash flow per share for the past 10 years together and divide the count will get our Cyclically Adjusted FCF per Share, which is €-251.24 for the trailing ten years ended in Mar. 2026.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted FCF Growth Rate using Cyclically Adjusted FCF per Share data.

As of today (2026-07-10), Synlogic's current stock price is €3.63. Synlogic's Cyclically Adjusted FCF per Share for the quarter that ended in Mar. 2026 was €-251.24. Synlogic's Cyclically Adjusted Price-to-FCF of today is .


Synlogic  (STU:MIN) Cyclically Adjusted FCF per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted FCF per Share may underestimate the company's free cash flow. Cyclically Adjusted Price-to-FCF can seem to be too high even the actual Price-to-Free-Cash-Flow is low.

For the Cyclically Adjusted Price-to-FCF, the free cash flow per share of the past 10 years are inflation-adjusted and averaged. The result is used for P/FCF calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted Price-to-FCF is also called CAPFCF Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted free cash flow per share of a company over the past 10 years.


Be Aware

Cyclically Adjusted Price-to-FCF works better for cyclical companies. It gives you a better idea on the company's real free cash flow value.


Synlogic Cyclically Adjusted FCF per Share Related Terms


Synlogic Cyclically Adjusted FCF per Share Historical Data

* Premium members only.

The historical data trend for Synlogic's Cyclically Adjusted FCF per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Synlogic Cyclically Adjusted FCF per Share Chart

Synlogic Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted FCF per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -172.74 -154.57

Synlogic Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted FCF per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -173.89 -159.83 -114.10 -154.57 -251.24

STU:MIN vs ASBP, PMCB, ERNA: Cyclically Adjusted FCF per Share Comparison

For the Biotechnology subindustry, Synlogic's Cyclically Adjusted Price-to-FCF, along with its competitors' market caps and Cyclically Adjusted Price-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Synlogic Cyclically Adjusted Price-to-FCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Synlogic's Cyclically Adjusted Price-to-FCF distribution charts can be found below:

* The bar in red indicates where Synlogic's Cyclically Adjusted Price-to-FCF falls into.


STU:MIN
30GF Score
Synlogic Inc STU:MIN
Cyclically Adjusted FCF per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Synlogic Cyclically Adjusted FCF per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted FCF per Share and the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years.

What is Cyclically Adjusted FCF per Share? How do we calculate Cyclically Adjusted FCF per Share?

Cyclically Adjusted FCF per Share is the average of the inflation adjusted Free Cash Flow per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted FCF per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the free cash flow per share from 2001 through 2010.

We adjusted the 2001 free cash flow per share data with the total inflation from 2001 through 2010 to the equivalent free cash flow in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's free cash flow is $1 a share in 2001, then the 2001's equivalent free cash flow in 2010 is $1.4 a share. If Wal-Mart's free cash flow is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 free cash flow in 2010 is $1.35. So on and so forth, you get the equivalent free cash flow per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted FCF per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Synlogic's adjusted Free Cash Flow per Share data for the three months ended in Mar. 2026 was:

Adj_FreeCashFlowPerShare= Free Cash Flow per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.039/330.2130*330.2130
=-0.039

Current CPI (Mar. 2026) = 330.2130.

Synlogic Quarterly Data

Free Cash Flow per Share CPI Adj_FreeCashFlowPerShare
201606 -24.864 241.018 -34.066
201609 -26.096 241.428 -35.693
201612 -29.141 241.432 -39.857
201703 -15.126 243.801 -20.487
201706 -54.563 244.955 -73.554
201709 -16.054 246.819 -21.478
201712 -7.063 246.524 -9.461
201803 -9.019 249.554 -11.934
201806 -6.103 251.989 -7.998
201809 -5.625 252.439 -7.358
201812 -5.403 251.233 -7.102
201903 -7.023 254.202 -9.123
201906 -19.991 256.143 -25.772
201909 -4.258 256.759 -5.476
201912 -4.580 256.974 -5.885
202003 -5.054 258.115 -6.466
202006 -3.444 257.797 -4.411
202009 -2.898 260.280 -3.677
202012 -3.228 260.474 -4.092
202103 -4.245 264.877 -5.292
202106 -2.738 271.696 -3.328
202109 -3.272 274.310 -3.939
202112 -2.435 278.802 -2.884
202203 -3.019 287.504 -3.467
202206 -2.700 296.311 -3.009
202209 -3.258 296.808 -3.625
202212 -2.490 296.797 -2.770
202303 -4.391 301.836 -4.804
202306 -2.301 305.109 -2.490
202309 -2.583 307.789 -2.771
202312 -0.555 306.746 -0.597
202403 -1.201 312.332 -1.270
202406 -1.096 314.175 -1.152
202409 -0.048 315.301 -0.050
202412 -0.044 315.605 -0.046
202503 -0.120 319.799 -0.124
202506 -0.028 322.561 -0.029
202509 -0.099 324.800 -0.101
202512 -0.064 324.054 -0.065
202603 -0.039 330.213 -0.039

Add all the adjusted free cash flow per share together and divide 10 will get our Cyclically Adjusted FCF per Share.

What does a Cyclically Adjusted FCF per Share of €-251.24 mean?
Synlogic (STU:MIN) has a Cyclically Adjusted FCF per Share of €-251.24 as of Mar. 2026. Cyclically Adjusted FCF per Share represents the company's inflation-adjusted FCF per share over a 10-year period. View historical data on Synlogic and its competitors.
Is Synlogic's Cyclically Adjusted FCF per Share too high?
Synlogic's current Cyclically Adjusted FCF per Share is €-251.24. Overall, Synlogic has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Synlogic's Cyclically Adjusted FCF per Share compare to ASBP and PMCB?
Synlogic's Cyclically Adjusted FCF per Share of €-251.24 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted FCF per Share for a Biotechnology company?
A good Cyclically Adjusted FCF per Share depends on the Biotechnology industry context. However, Cyclically Adjusted FCF per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted FCF per Share mean?
A high Cyclically Adjusted FCF per Share can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted FCF per Share represents the company's inflation-adjusted FCF per share over a 10-year period. View historical data on Synlogic and its competitors. Synlogic's current Cyclically Adjusted FCF per Share is €-251.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Synlogic stock overvalued right now?
Synlogic (STU:MIN) has a current Cyclically Adjusted FCF per Share of €-251.24. The stock's GF Value™ is €0.15, compared to a current price of €3.63 — trading 2320% above its estimated fair value. The current Cyclically Adjusted FCF per Share is €-251.24. Synlogic's overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted FCF per Share calculated?
Cyclically Adjusted FCF per Share is calculated from a company's financial statements. For Synlogic (STU:MIN), the current Cyclically Adjusted FCF per Share is €-251.24 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Synlogic (STU:MIN) Overvalued in 2026?

Based on GuruFocus' analysis, Synlogic stock appears to be overvalued. The current stock price of €3.63 is trading 2320% above its estimated GF Value™ of €0.15.

Key valuation signals for STU:MIN:

  • Cyclically Adjusted FCF per Share: €-251.24
  • GF Value™: €0.15 vs. price of €3.63 (2320% above fair value)
  • GF Score™: 30/100 with 1 warning sign

No single metric tells the full story. See the STU:MIN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Synlogic Business Description

Other Exchanges SYBX:USA0A8U:UK
Address PO Box 30, Winchester, MA, USA, 01890
Synlogic Inc is a biopharmaceutical company focuses on rare metabolic disorders, with a program in phenylketonuria (PKU) and homocystinuria (HCU). The company's pipeline includes therapeutics for enteric hyperoxaluria, gout, and cystinuria. Using a proprietary approach, the company engineer GI-restricted, oral medicines from well-characterized probiotics. The pipeline drug candidates includes: labafenogene marselecobac (SYNB1934); SYNB1353 Classical Homocystinuria (HCU); SYNB8802 Enteric Hyperoxaluria; and SYNB2081 Gout. Engineered to be non-colonizing and reversible, the company offer oral administration, simplifying shipping and storage. The company operates in one operating segment: Discovery and development of Synthetic Biotics.
30GF Score

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Cyclically Adjusted FCF per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.63
Price
€0.15
GF Value