ABEO (Abeona Therapeutics) Cyclically Adjusted PB Ratio: 0.19 (As of Aug. 10, 2026) — 46% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ABEO Abeona Therapeutics Inc ABEO
32 GF Score
Price $7.45
! 8 Warning Signs
View Full Analysis

What is Abeona Therapeutics Cyclically Adjusted PB Ratio?

Abeona Therapeutics ABEO +2.90% 32 Cyclically Adjusted PB Ratio is 0.19 as of Aug. 10, 2026, which is 46% above its 10-year median of 0.13. GuruFocus rates ABEO with a GF Score™ of 32/100. The stock has 8 warning signs investors should review. Among 692 Biotechnology companies, Abeona Therapeutics ranks better than 84.39% on this metric.

As of today (2026-08-10), Abeona Therapeutics's current share price is $7.45. Abeona Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $39.00. Abeona Therapeutics's Cyclically Adjusted PB Ratio for today is 0.19.

The historical rank and industry rank for Abeona Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

ABEO' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.1   Med: 0.13   Max: 0.19
Current: 0.19

During the past years, Abeona Therapeutics's highest Cyclically Adjusted PB Ratio was 0.19. The lowest was 0.10. And the median was 0.13.

ABEO's Cyclically Adjusted PB Ratio is ranked better than
84.39% of 692 companies
in the Biotechnology industry
Industry Median: 1.615 vs ABEO: 0.19

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Abeona Therapeutics's adjusted book value per share data for the three months ended in Mar. 2026 was $2.549. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $39.00 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Abeona Therapeutics  (NAS:ABEO) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Abeona Therapeutics Cyclically Adjusted PB Ratio Related Terms


Abeona Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Abeona Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Abeona Therapeutics Cyclically Adjusted PB Ratio Chart

Abeona Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.13 0.13

Abeona Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.11 0.13 0.13 0.13 0.11

ABEO vs RCKT, UPB, PALI: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Abeona Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Abeona Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Abeona Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Abeona Therapeutics's Cyclically Adjusted PB Ratio falls into.


ABEO
32GF Score
Abeona Therapeutics Inc ABEO
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Abeona Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Abeona Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=7.45/39.00
=0.19

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Abeona Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Abeona Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=2.549/330.2130*330.2130
=2.549

Current CPI (Mar. 2026) = 330.2130.

Abeona Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201606 46.860 241.018 64.202
201609 47.096 241.428 64.416
201612 61.552 241.432 84.186
201703 59.445 243.801 80.514
201706 55.294 244.955 74.539
201709 54.905 246.819 73.456
201712 90.671 246.524 121.452
201803 89.571 249.554 118.521
201806 85.005 251.989 111.393
201809 78.334 252.439 102.468
201812 69.888 251.233 91.859
201903 61.414 254.202 79.778
201906 54.396 256.143 70.126
201909 47.038 256.759 60.495
201912 53.342 256.974 68.545
202003 39.575 258.115 50.629
202006 35.699 257.797 45.727
202009 34.046 260.280 43.194
202012 26.671 260.474 33.812
202103 23.824 264.877 29.701
202106 20.762 271.696 25.234
202109 19.569 274.310 23.557
202112 7.196 278.802 8.523
202203 5.345 287.504 6.139
202206 3.422 296.311 3.814
202209 2.009 296.808 2.235
202212 1.510 296.797 1.680
202303 1.045 301.836 1.143
202306 0.435 305.109 0.471
202309 0.892 307.789 0.957
202312 0.559 306.746 0.602
202403 -0.322 312.332 -0.340
202406 1.758 314.175 1.848
202409 1.055 315.301 1.105
202412 0.965 315.605 1.010
202503 0.846 319.799 0.874
202506 3.192 322.561 3.268
202509 3.268 324.800 3.322
202512 2.893 324.054 2.948
202603 2.549 330.213 2.549

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.19 mean?
Abeona Therapeutics (ABEO) has a Cyclically Adjusted PB Ratio of 0.19 as of Aug. 10, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Abeona Therapeutics and its competitors. This is 46% above median its historical median of 0.13. Over the past decade, Abeona Therapeutics' Cyclically Adjusted PB Ratio has ranged from 0.10 to 0.19. According to the industry distribution chart, Abeona Therapeutics ranks #108 out of 692 companies in the Biotechnology industry, placing it in the top 15.6%.
Is Abeona Therapeutics' Cyclically Adjusted PB Ratio too high?
Abeona Therapeutics' current Cyclically Adjusted PB Ratio of 0.19 is 46% above median its 10-year median of 0.13. Over the past 10 years, this metric has ranged from a low of 0.10 to a high of 0.19. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Abeona Therapeutics' value of 0.19 is 88.2% below this industry median. Based on the distribution chart, Abeona Therapeutics ranks #108 out of 692 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Abeona Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Abeona Therapeutics' Cyclically Adjusted PB Ratio compare to RCKT and UPB?
According to the Biotechnology industry distribution chart, Abeona Therapeutics ranks #108 out of 692 companies for Cyclically Adjusted PB Ratio. This places Abeona Therapeutics in the top 16% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.62. Abeona Therapeutics' value of 0.19 is 88.2% below this benchmark. Historically, Abeona Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 0.10 to 0.19 over the past decade. While the company's 10-year median is 0.13 vs. the industry median of 1.62, Abeona Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 692 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Abeona Therapeutics's current Cyclically Adjusted PB Ratio of 0.19 is 88.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Abeona Therapeutics and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Abeona Therapeutics's current Cyclically Adjusted PB Ratio is 0.19, which is 46% above median its own 10-year median of 0.13. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Abeona Therapeutics stock overvalued right now?
Abeona Therapeutics (ABEO) has a current Cyclically Adjusted PB Ratio of 0.19. The current Cyclically Adjusted PB Ratio is 0.19, which is 46% above median its 10-year median of 0.13 and 88.2% below the Biotechnology industry median of 1.62. Abeona Therapeutics' overall GF Score™ is 32/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Abeona Therapeutics (ABEO), the current Cyclically Adjusted PB Ratio is 0.19 as of Aug. 10, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Abeona Therapeutics Business Description

Other Exchanges 0H7R:UKPCJ:Germany
Address 6555 Carnegie Avenue, 4th Floor, Cleveland, OH, USA, 44103
Abeona Therapeutics Inc is a commercial-stage biopharmaceutical company. The company is focused on developing cell and gene therapies for life-threatening diseases. The company's ZEVASKYN (prademagene zamikeracel) is an autologous cell-based gene therapy for the treatment of wounds in adults and pediatric patients with recessive dystrophic epidermolysis bullosa (RDEB). The company's development portfolio includes adeno-associated virus (AAV)-based gene therapies for ophthalmic diseases with high unmet medical need.
32GF Score

Get the complete analysis for ABEO

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$7.45
Price