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ADC TherapeuticsADCT -6.67%41 Cyclically Adjusted PB Ratio is 1.07 as of Jul. 21, 2026, which is 67% below its 10-year median of 3.27. GuruFocus rates ADCT with a GF Score™ of 41/100 and a GF Value™ of $2.09 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 757 Drug Manufacturers companies, ADC Therapeutics ranks better than 68.3% on this metric.
The historical rank and industry rank for ADC Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:
ADCT'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.07 Med: 3.27 Max: 3.5
Current: 1.07
During the past 10 years, ADC Therapeutics's highest Cyclically Adjusted PB Ratio was 3.50. The lowest was 1.07. And the median was 3.27.
ADCT's Cyclically Adjusted PB Ratio is ranked better than 68.3% of 757
companies
in the Drug Manufacturers industry
Industry Median: 1.86
vs ADCT: 1.07
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
ADC Therapeutics's adjusted book value per share data of for the fiscal year that ended in Dec25 was $-1.478. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $1.18 for the trailing ten years ended in Dec25.
Shiller PE for Stocks: The True Measure of Stock Valuation
ADC Therapeutics (NYSE:ADCT) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
ADC Therapeutics Cyclically Adjusted PB Ratio Related Terms
ADC Therapeutics Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for ADC Therapeutics's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
ADC Therapeutics Cyclically Adjusted PB Ratio Chart
ADCT vs GNLX, VXRT, COYA: Cyclically Adjusted PB Ratio Comparison
For the Drug Manufacturers - Specialty & Generic subindustry, ADC Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
ADC Therapeutics Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, ADC Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where ADC Therapeutics's Cyclically Adjusted PB Ratio falls into.
ADC Therapeutics Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
ADC Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 1.07 mean?
ADC Therapeutics (ADCT) has a Cyclically Adjusted PB Ratio of 1.07 as of Jul. 21, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on ADC Therapeutics and its competitors. This is 67% below median its historical median of 3.27. Over the past decade, ADC Therapeutics' Cyclically Adjusted PB Ratio has ranged from 1.07 to 3.50. According to the industry distribution chart, ADC Therapeutics ranks #240 out of 757 companies in the Drug Manufacturers industry, placing it in the top 31.7%.
Is ADC Therapeutics' Cyclically Adjusted PB Ratio too high?
ADC Therapeutics' current Cyclically Adjusted PB Ratio of 1.07 is 67% below median its 10-year median of 3.27. Over the past 10 years, this metric has ranged from a low of 1.07 to a high of 3.50. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.86. ADC Therapeutics' value of 1.07 is 42.5% below this industry median. Based on the distribution chart, ADC Therapeutics ranks #240 out of 757 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, ADC Therapeutics has a GF Score™ of 41/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does ADC Therapeutics' Cyclically Adjusted PB Ratio compare to GNLX and VXRT?
According to the Drug Manufacturers industry distribution chart, ADC Therapeutics ranks #240 out of 757 companies for Cyclically Adjusted PB Ratio. This puts ADC Therapeutics in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.86. ADC Therapeutics' value of 1.07 is 42.5% below this benchmark. Historically, ADC Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 1.07 to 3.50 over the past decade. While the company's 10-year median is 3.27 vs. the industry median of 1.86, ADC Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.86, based on 757 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. ADC Therapeutics's current Cyclically Adjusted PB Ratio of 1.07 is 42.5% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on ADC Therapeutics and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.86 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. ADC Therapeutics's current Cyclically Adjusted PB Ratio is 1.07, which is 67% below median its own 10-year median of 3.27. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ADC Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, ADC Therapeutics (ADCT) is currently considered Possible Value Trap. The stock's GF Value™ is $2.09, compared to a current price of $1.26 — trading 39.7% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.07, which is 67% below median its 10-year median of 3.27 and 42.5% below the Drug Manufacturers industry median of 1.86. ADC Therapeutics' overall GF Score™ is 41/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For ADC Therapeutics (ADCT), the current Cyclically Adjusted PB Ratio is 1.07 as of Jul. 21, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is ADC Therapeutics (ADCT) Overvalued in 2026?
Based on GuruFocus' analysis, ADC Therapeutics stock appears to be undervalued.
The current stock price of $1.26 is trading 39.7% below its estimated GF Value™ of $2.09.
GuruFocus considers ADC Therapeutics to be Possible Value Trap.
Key valuation signals for ADCT:
Cyclically Adjusted PB Ratio: 1.07 (67% below median its 10-year median of 3.27)
GF Value™: $2.09 vs. price of $1.26 (39.7% below fair value)
Industry Position: 42.5% below the Drug Manufacturers median (#240 of 757)
No single metric tells the full story. See the ADCT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
ADC Therapeutics SA is a commercial-stage oncology-focused biotechnology company. It is involved in the development of antibody-drug conjugates for patients suffering from hematological malignancies and solid tumors. The company's FDA-approved and marketed product, ZYNLONTA (loncastuximab tesirine), is a CD19-directed antibody and alkylating agent conjugate indicated for the treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy. Additionally, the company's development pipeline comprises LOTIS-2, LOTIS-5, LOTIS-7, and ADCT-241, being developed as potential therapies for different cancer diseases. Geographically, the firm generates maximum revenue from the United States, followed by Europe, the Middle East and Africa (EMEA).
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