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Bio-Rad LaboratoriesBIO +2.65%71 Cyclically Adjusted PB Ratio is 1.19 as of Aug. 03, 2026, which is 61% below its 10-year median of 3.02. GuruFocus rates BIO with a GF Score™ of 71/100 and a GF Value™ of $317.78 (Fairly Valued). The stock has 8 warning signs investors should review. Among 521 Medical Devices & Instruments companies, Bio-Rad Laboratories ranks better than 64.68% on this metric.
The historical rank and industry rank for Bio-Rad Laboratories's Cyclically Adjusted PB Ratio or its related term are showing as below:
BIO'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.86 Med: 3.02 Max: 5.8
Current: 1.16
During the past years, Bio-Rad Laboratories's highest Cyclically Adjusted PB Ratio was 5.80. The lowest was 0.86. And the median was 3.02.
BIO's Cyclically Adjusted PB Ratio is ranked better than 64.68% of 521
companies
in the Medical Devices & Instruments industry
Industry Median: 1.78
vs BIO: 1.16
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Bio-Rad Laboratories's adjusted book value per share data for the three months ended in Mar. 2026 was $255.379. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $279.74 for the trailing ten years ended in Mar. 2026.
Shiller PE for Stocks: The True Measure of Stock Valuation
Bio-Rad Laboratories (NYSE:BIO) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Bio-Rad Laboratories Cyclically Adjusted PB Ratio Related Terms
Bio-Rad Laboratories Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for Bio-Rad Laboratories's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Bio-Rad Laboratories Cyclically Adjusted PB Ratio Chart
BIO vs GKOS, BRKR, GMED: Cyclically Adjusted PB Ratio Comparison
For the Medical Devices subindustry, Bio-Rad Laboratories's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Bio-Rad Laboratories Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry
For the Medical Devices & Instruments industry and Healthcare sector, Bio-Rad Laboratories's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Bio-Rad Laboratories's Cyclically Adjusted PB Ratio falls into.
Bio-Rad Laboratories Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 1.19 mean?
Bio-Rad Laboratories (BIO) has a Cyclically Adjusted PB Ratio of 1.19 as of Aug. 03, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Bio-Rad Laboratories and its competitors. This is 61% below median its historical median of 3.02. Over the past decade, Bio-Rad Laboratories' Cyclically Adjusted PB Ratio has ranged from 0.86 to 5.80. According to the industry distribution chart, Bio-Rad Laboratories ranks #184 out of 521 companies in the Medical Devices & Instruments industry, placing it in the top 35.3%.
Is Bio-Rad Laboratories' Cyclically Adjusted PB Ratio too high?
Bio-Rad Laboratories' current Cyclically Adjusted PB Ratio of 1.19 is 61% below median its 10-year median of 3.02. Over the past 10 years, this metric has ranged from a low of 0.86 to a high of 5.80. The Medical Devices & Instruments industry median Cyclically Adjusted PB Ratio is 1.78. Bio-Rad Laboratories' value of 1.19 is 33.1% below this industry median. Based on the distribution chart, Bio-Rad Laboratories ranks #184 out of 521 companies in the Medical Devices & Instruments industry, which is above the industry midpoint. Overall, Bio-Rad Laboratories has a GF Score™ of 71/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Bio-Rad Laboratories' Cyclically Adjusted PB Ratio compare to GKOS and BRKR?
According to the Medical Devices & Instruments industry distribution chart, Bio-Rad Laboratories ranks #184 out of 521 companies for Cyclically Adjusted PB Ratio. This puts Bio-Rad Laboratories in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.78. Bio-Rad Laboratories' value of 1.19 is 33.1% below this benchmark. Historically, Bio-Rad Laboratories' own Cyclically Adjusted PB Ratio has ranged from 0.86 to 5.80 over the past decade. While the company's 10-year median is 3.02 vs. the industry median of 1.78, Bio-Rad Laboratories has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Devices & Instruments company?
The median Cyclically Adjusted PB Ratio among Medical Devices & Instruments companies is 1.78, based on 521 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Bio-Rad Laboratories's current Cyclically Adjusted PB Ratio of 1.19 is 33.1% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Bio-Rad Laboratories and its competitors. For the Medical Devices & Instruments industry, the median Cyclically Adjusted PB Ratio is 1.78 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Bio-Rad Laboratories's current Cyclically Adjusted PB Ratio is 1.19, which is 61% below median its own 10-year median of 3.02. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Bio-Rad Laboratories stock overvalued right now?
Based on GuruFocus' analysis, Bio-Rad Laboratories (BIO) is currently considered Fairly Valued. The stock's GF Value™ is $317.78, compared to a current price of $334.12 — trading 5.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.19, which is 61% below median its 10-year median of 3.02 and 33.1% below the Medical Devices & Instruments industry median of 1.78. Bio-Rad Laboratories' overall GF Score™ is 71/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Bio-Rad Laboratories (BIO), the current Cyclically Adjusted PB Ratio is 1.19 as of Aug. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Bio-Rad Laboratories (BIO) Overvalued in 2026?
Based on GuruFocus' analysis, Bio-Rad Laboratories stock appears to be overvalued.
The current stock price of $334.12 is trading 5.1% above its estimated GF Value™ of $317.78.
GuruFocus considers Bio-Rad Laboratories to be Fairly Valued.
Key valuation signals for BIO:
Cyclically Adjusted PB Ratio: 1.19 (61% below median its 10-year median of 3.02)
GF Value™: $317.78 vs. price of $334.12 (5.1% above fair value)
Industry Position: 33.1% below the Medical Devices & Instruments median (#184 of 521)
No single metric tells the full story. See the BIO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Bio-Rad Laboratories, headquartered in Hercules, California, develops, manufactures, and sells products and solutions for the clinical diagnostics and life sciences markets. In clinical diagnostics (60% of sales), Bio-Rad sells test systems and specialized quality controls for clinical laboratories. In life sciences (40% of sales), it develops and manufactures instruments and reagents used in research, biopharmaceutical production, and food testing and has a leadership position in dPCR technology. The company is geographically diverse, with major markets in the Americas (about 40% of sales), Europe (about 30%), Asia (about 30%), and other. Bio-Rad owns approximately 33% of Sartorius, a lab and bioprocessing supplier that specializes in single-use technology used in biologics manufacturing.
71GF Score
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