Biogen (BUE:BIIB) Cyclically Adjusted PB Ratio: 2.11 (As of Aug. 09, 2026) — 56% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

BUE:BIIB Biogen Inc BUE:BIIB
62 GF Score
Price ARS25,200.00
GF Value ARS23,569.88
Valuation Fairly Valued
! 10 Warning Signs
View Full Analysis

What is Biogen Cyclically Adjusted PB Ratio?

Biogen BUE:BIIB +0.56% 62 Cyclically Adjusted PB Ratio is 2.11 as of Aug. 09, 2026, which is 56% below its 10-year median of 4.80. GuruFocus rates BUE:BIIB with a GF Score™ of 62/100 and a GF Value™ of ARS23,569.88 (Fairly Valued). The stock has 10 warning signs investors should review. Among 733 Drug Manufacturers companies, Biogen ranks worse than 55.39% on this metric.

As of today (2026-08-09), Biogen's current share price is ARS25200.00. Biogen's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was ARS11,932.61. Biogen's Cyclically Adjusted PB Ratio for today is 2.11.

The historical rank and industry rank for Biogen's Cyclically Adjusted PB Ratio or its related term are showing as below:

BUE:BIIB' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.31   Med: 4.8   Max: 9.94
Current: 2.1

During the past years, Biogen's highest Cyclically Adjusted PB Ratio was 9.94. The lowest was 1.31. And the median was 4.80.

BUE:BIIB's Cyclically Adjusted PB Ratio is ranked worse than
55.39% of 733 companies
in the Drug Manufacturers industry
Industry Median: 1.81 vs BUE:BIIB: 2.10

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Biogen's adjusted book value per share data for the three months ended in Jun. 2026 was ARS189,016.347. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is ARS11,932.61 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Biogen  (BUE:BIIB) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Biogen Cyclically Adjusted PB Ratio Related Terms


Biogen Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Biogen's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biogen Cyclically Adjusted PB Ratio Chart

Biogen Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.93 3.96 3.32 1.79 1.88

Biogen Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.40 1.52 1.88 1.90 2.18

BUE:BIIB vs OGN, AMRN, SCLX: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - General subindustry, Biogen's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Biogen Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Biogen's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Biogen's Cyclically Adjusted PB Ratio falls into.


BUE:BIIB
62GF Score
Biogen Inc BUE:BIIB
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Biogen Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Biogen's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=25200.00/11932.61
=2.11

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biogen's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Biogen's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=189016.347/333.9520*333.9520
=189,016.347

Current CPI (Jun. 2026) = 333.9520.

Biogen Quarterly Data

Book Value per Share CPI Adj_Book
201609 830.769 241.428 1,149.150
201612 890.977 241.432 1,232.411
201703 826.971 243.801 1,132.762
201706 903.443 244.955 1,231.682
201709 1,065.652 246.819 1,441.853
201712 1,138.730 246.524 1,542.573
201803 1,341.978 249.554 1,795.829
201806 1,517.982 251.989 2,011.727
201809 2,514.342 252.439 3,326.227
201812 2,493.195 251.233 3,314.085
201903 2,769.522 254.202 3,638.395
201906 3,131.616 256.143 4,082.912
201909 4,303.104 256.759 5,596.806
201912 4,578.479 256.974 5,949.988
202003 4,654.975 258.115 6,022.657
202006 4,890.673 257.797 6,335.411
202009 5,189.805 260.280 6,658.774
202012 5,713.848 260.474 7,325.687
202103 6,389.459 264.877 8,055.711
202106 6,831.170 271.696 8,396.454
202109 6,942.380 274.310 8,451.831
202112 7,485.763 278.802 8,966.527
202203 8,183.789 287.504 9,505.929
202206 9,838.967 296.311 11,088.831
202209 12,327.470 296.808 13,870.190
202212 15,598.319 296.797 17,551.019
202303 18,822.641 301.836 20,825.411
202306 23,978.287 305.109 26,245.037
202309 34,980.027 307.789 37,953.436
202312 36,870.831 306.746 40,140.989
202403 88,514.867 312.332 94,641.973
202406 98,332.335 314.175 104,522.257
202409 106,720.204 315.301 113,033.024
202412 115,861.076 315.605 122,596.404
202503 123,548.951 319.799 129,016.724
202506 142,808.120 322.561 147,851.282
202509 168,548.131 324.800 173,297.369
202512 180,514.606 324.054 186,028.297
202603 176,691.382 330.213 178,692.058
202606 189,016.347 333.952 189,016.347

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 2.11 mean?
Biogen (BUE:BIIB) has a Cyclically Adjusted PB Ratio of 2.11 as of Aug. 09, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Biogen and its competitors. This is 56% below median its historical median of 4.80. Over the past decade, Biogen's Cyclically Adjusted PB Ratio has ranged from 1.31 to 9.94. According to the industry distribution chart, Biogen ranks #406 out of 733 companies in the Drug Manufacturers industry, placing it in the top 55.4%.
Is Biogen's Cyclically Adjusted PB Ratio too high?
Biogen's current Cyclically Adjusted PB Ratio of 2.11 is 56% below median its 10-year median of 4.80. Over the past 10 years, this metric has ranged from a low of 1.31 to a high of 9.94. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.81. Biogen's value of 2.11 is 16.6% above this industry median. Based on the distribution chart, Biogen ranks #406 out of 733 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Biogen has a GF Score™ of 62/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Biogen's Cyclically Adjusted PB Ratio compare to OGN and AMRN?
According to the Drug Manufacturers industry distribution chart, Biogen ranks #406 out of 733 companies for Cyclically Adjusted PB Ratio. This places Biogen in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.81. Biogen's value of 2.11 is 16.6% above this benchmark. Historically, Biogen's own Cyclically Adjusted PB Ratio has ranged from 1.31 to 9.94 over the past decade. While the company's 10-year median is 4.80 vs. the industry median of 1.81, Biogen has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.81, based on 733 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Biogen's current Cyclically Adjusted PB Ratio of 2.11 is 16.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Biogen and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.81 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Biogen's current Cyclically Adjusted PB Ratio is 2.11, which is 56% below median its own 10-year median of 4.80. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Biogen stock overvalued right now?
Based on GuruFocus' analysis, Biogen (BUE:BIIB) is currently considered Fairly Valued. The stock's GF Value™ is ARS23,569.88, compared to a current price of ARS25,200.00 — trading 6.9% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 2.11, which is 56% below median its 10-year median of 4.80 and 16.6% above the Drug Manufacturers industry median of 1.81. Biogen's overall GF Score™ is 62/100 with 10 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Biogen (BUE:BIIB), the current Cyclically Adjusted PB Ratio is 2.11 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Biogen (BUE:BIIB) Overvalued in 2026?

Based on GuruFocus' analysis, Biogen stock appears to be overvalued. The current stock price of ARS25,200.00 is trading 6.9% above its estimated GF Value™ of ARS23,569.88. GuruFocus considers Biogen to be Fairly Valued.

Key valuation signals for BUE:BIIB:

  • Cyclically Adjusted PB Ratio: 2.11 (56% below median its 10-year median of 4.80)
  • GF Value™: ARS23,569.88 vs. price of ARS25,200.00 (6.9% above fair value)
  • GF Score™: 62/100 with 10 warning signs
  • Industry Position: 16.6% above the Drug Manufacturers median (#406 of 733)

No single metric tells the full story. See the BUE:BIIB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Biogen Business Description

Address 225 Binney Street, Cambridge, MA, USA, 02142
Biogen is an established biopharmaceutical company focused on treatments for neurodegenerative and rare diseases. Its declining multiple sclerosis franchise is its largest revenue generator and contributed 40% of total revenue in 2025. Biogen also generates significant revenue from its CD20 collaboration agreements with Roche (19% of total in 2025), which includes oncology drugs Rituxan and Gazyva and multiple sclerosis drug Ocrevus. Biogen's newer franchises include Spinraza (spinal muscular atrophy, with partner Ionis), Leqembi (Alzheimer's disease, collabroation revenue from its partner Eisai), Skyclarys (Friedreich's ataxia, Reata), Zurzuvae (postpartum depression, Sage), and Qalsody (amyotrophic lateral sclerosis, Ionis).
62GF Score

Get the complete analysis for BUE:BIIB

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

ARS25,200.00
Price
ARS23,569.88
GF Value