Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Instituto RosenbuschBUE:ROSE +0.31%37 Cyclically Adjusted PB Ratio is 8.61 as of Aug. 07, 2026, which is 90% above its 10-year median of 4.53. GuruFocus rates BUE:ROSE with a GF Score™ of 37/100 and a GF Value™ of ARS62.66 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 737 Drug Manufacturers companies, Instituto Rosenbusch ranks worse than 90.64% on this metric.
The historical rank and industry rank for Instituto Rosenbusch's Cyclically Adjusted PB Ratio or its related term are showing as below:
BUE:ROSE'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.9 Med: 4.53 Max: 21.22
Current: 8.26
During the past years, Instituto Rosenbusch's highest Cyclically Adjusted PB Ratio was 21.22. The lowest was 1.90. And the median was 4.53.
BUE:ROSE's Cyclically Adjusted PB Ratio is ranked worse than 90.64% of 737
companies
in the Drug Manufacturers industry
Industry Median: 1.77
vs BUE:ROSE: 8.26
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Instituto Rosenbusch's adjusted book value per share data for the three months ended in Dec. 2025 was ARS-18.788. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is ARS18.65 for the trailing ten years ended in Dec. 2025.
Shiller PE for Stocks: The True Measure of Stock Valuation
Instituto Rosenbusch (BUE:ROSE) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Instituto Rosenbusch Cyclically Adjusted PB Ratio Related Terms
Instituto Rosenbusch Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for Instituto Rosenbusch's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Instituto Rosenbusch Cyclically Adjusted PB Ratio Chart
BUE:ROSE vs ZTS, UTHR, VTRS: Cyclically Adjusted PB Ratio Comparison
For the Drug Manufacturers - Specialty & Generic subindustry, Instituto Rosenbusch's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Instituto Rosenbusch Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Instituto Rosenbusch's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Instituto Rosenbusch's Cyclically Adjusted PB Ratio falls into.
Instituto Rosenbusch Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 8.61 mean?
Instituto Rosenbusch (BUE:ROSE) has a Cyclically Adjusted PB Ratio of 8.61 as of Aug. 07, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Instituto Rosenbusch and its competitors. This is 90% above median its historical median of 4.53. Over the past decade, Instituto Rosenbusch's Cyclically Adjusted PB Ratio has ranged from 1.90 to 21.22. According to the industry distribution chart, Instituto Rosenbusch ranks #668 out of 737 companies in the Drug Manufacturers industry, placing it in the top 90.6%.
Is Instituto Rosenbusch's Cyclically Adjusted PB Ratio too high?
Instituto Rosenbusch's current Cyclically Adjusted PB Ratio of 8.61 is 90% above median its 10-year median of 4.53. Over the past 10 years, this metric has ranged from a low of 1.90 to a high of 21.22. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.77. Instituto Rosenbusch's value of 8.61 is 386.4% above this industry median. Based on the distribution chart, Instituto Rosenbusch ranks #668 out of 737 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Instituto Rosenbusch has a GF Score™ of 37/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Instituto Rosenbusch's Cyclically Adjusted PB Ratio compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, Instituto Rosenbusch ranks #668 out of 737 companies for Cyclically Adjusted PB Ratio. This places Instituto Rosenbusch in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.77. Instituto Rosenbusch's value of 8.61 is 386.4% above this benchmark. Historically, Instituto Rosenbusch's own Cyclically Adjusted PB Ratio has ranged from 1.90 to 21.22 over the past decade. While the company's 10-year median is 4.53 vs. the industry median of 1.77, Instituto Rosenbusch has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.77, based on 737 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Instituto Rosenbusch's current Cyclically Adjusted PB Ratio of 8.61 is 386.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Instituto Rosenbusch and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.77 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Instituto Rosenbusch's current Cyclically Adjusted PB Ratio is 8.61, which is 90% above median its own 10-year median of 4.53. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Instituto Rosenbusch stock overvalued right now?
Based on GuruFocus' analysis, Instituto Rosenbusch (BUE:ROSE) is currently considered Significantly Overvalued. The stock's GF Value™ is ARS62.66, compared to a current price of ARS160.50 — trading 156.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 8.61, which is 90% above median its 10-year median of 4.53 and 386.4% above the Drug Manufacturers industry median of 1.77. Instituto Rosenbusch's overall GF Score™ is 37/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Instituto Rosenbusch (BUE:ROSE), the current Cyclically Adjusted PB Ratio is 8.61 as of Aug. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Instituto Rosenbusch (BUE:ROSE) Overvalued in 2026?
Based on GuruFocus' analysis, Instituto Rosenbusch stock appears to be overvalued.
The current stock price of ARS160.50 is trading 156.1% above its estimated GF Value™ of ARS62.66.
GuruFocus considers Instituto Rosenbusch to be Significantly Overvalued.
Key valuation signals for BUE:ROSE:
Cyclically Adjusted PB Ratio: 8.61 (90% above median its 10-year median of 4.53)
GF Value™: ARS62.66 vs. price of ARS160.50 (156.1% above fair value)
Industry Position: 386.4% above the Drug Manufacturers median (#668 of 737)
No single metric tells the full story. See the BUE:ROSE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Instituto Rosenbusch SA is a pharmaceutical company based in Argentina. The company is engaged in the processing and industrialization of biological, chemical, pharmaceutical products of any kind, nature or destination, preferably for veterinary use or intended to combat pests and diseases of the agricultural exploitation. The company has line of products such as Biologicals and pharmaceuticals. Biologicals offer Campy 3, Cultivac 6M and Bovine Antibrucelosis. Pharmaceuticals offer Diclosan A Intrammamary, Diclosan S Intrammamary and Mastilina V-S.
37GF Score
Get the complete analysis for BUE:ROSE
Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
BUE:ROSE has been successfully added to your 
