COCP (Cocrystal Pharma) Cyclically Adjusted PB Ratio: 0.04 (As of Jul. 11, 2026) — 60% Below Median


COCP Cocrystal Pharma Inc COCP
23 GF Score
Price $1.01
! 3 Warning Signs
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What is Cocrystal Pharma Cyclically Adjusted PB Ratio?

Cocrystal Pharma COCP +1.00% 23 Cyclically Adjusted PB Ratio is 0.04 as of Jul. 11, 2026, which is 60% below its 10-year median of 0.10. GuruFocus rates COCP with a GF Score™ of 23/100. The stock has 3 warning signs investors should review. Among 699 Biotechnology companies, Cocrystal Pharma ranks better than 94.99% on this metric.

As of today (2026-07-11), Cocrystal Pharma's current share price is $1.01. Cocrystal Pharma's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $26.44. Cocrystal Pharma's Cyclically Adjusted PB Ratio for today is 0.04.

The historical rank and industry rank for Cocrystal Pharma's Cyclically Adjusted PB Ratio or its related term are showing as below:

COCP' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.03   Med: 0.1   Max: 1.39
Current: 0.04

During the past years, Cocrystal Pharma's highest Cyclically Adjusted PB Ratio was 1.39. The lowest was 0.03. And the median was 0.10.

COCP's Cyclically Adjusted PB Ratio is ranked better than
94.99% of 699 companies
in the Biotechnology industry
Industry Median: 1.66 vs COCP: 0.04

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Cocrystal Pharma's adjusted book value per share data for the three months ended in Mar. 2026 was $0.299. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $26.44 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Cocrystal Pharma  (NAS:COCP) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Cocrystal Pharma Cyclically Adjusted PB Ratio Related Terms


Cocrystal Pharma Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Cocrystal Pharma's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cocrystal Pharma Cyclically Adjusted PB Ratio Chart

Cocrystal Pharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.26 0.06 0.04 0.05 0.03

Cocrystal Pharma Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.04 0.04 0.04 0.03 0.04

COCP vs HOOK, LNAI, CYCN: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Cocrystal Pharma's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cocrystal Pharma Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cocrystal Pharma's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Cocrystal Pharma's Cyclically Adjusted PB Ratio falls into.


COCP
23GF Score
Cocrystal Pharma Inc COCP
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Cocrystal Pharma Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Cocrystal Pharma's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=1.01/26.44
=0.04

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cocrystal Pharma's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Cocrystal Pharma's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.299/330.2130*330.2130
=0.299

Current CPI (Mar. 2026) = 330.2130.

Cocrystal Pharma Quarterly Data

Book Value per Share CPI Adj_Book
201606 85.293 241.018 116.858
201609 84.630 241.428 115.753
201612 51.598 241.432 70.572
201703 50.420 243.801 68.291
201706 50.563 244.955 68.162
201709 49.431 246.819 66.133
201712 52.101 246.524 69.788
201803 51.223 249.554 67.779
201806 45.167 251.989 59.188
201809 44.467 252.439 58.167
201812 26.809 251.233 35.237
201903 28.015 254.202 36.392
201906 27.483 256.143 35.430
201909 26.848 256.759 34.529
201912 8.777 256.974 11.278
202003 9.305 258.115 11.904
202006 8.528 257.797 10.924
202009 8.781 260.280 11.140
202012 8.945 260.474 11.340
202103 8.740 264.877 10.896
202106 10.434 271.696 12.681
202109 9.974 274.310 12.007
202112 9.548 278.802 11.309
202203 9.059 287.504 10.405
202206 6.081 296.311 6.777
202209 5.392 296.808 5.999
202212 4.859 296.797 5.406
202303 4.258 301.836 4.658
202306 3.409 305.109 3.689
202309 3.017 307.789 3.237
202312 2.593 306.746 2.791
202403 2.220 312.332 2.347
202406 1.709 314.175 1.796
202409 1.249 315.301 1.308
202412 0.936 315.605 0.979
202503 0.718 319.799 0.741
202506 0.524 322.561 0.536
202509 0.588 324.800 0.598
202512 0.459 324.054 0.468
202603 0.299 330.213 0.299

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.04 mean?
Cocrystal Pharma (COCP) has a Cyclically Adjusted PB Ratio of 0.04 as of Jul. 11, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Cocrystal Pharma and its competitors. This is 60% below median its historical median of 0.10. Over the past decade, Cocrystal Pharma's Cyclically Adjusted PB Ratio has ranged from 0.03 to 1.39. According to the industry distribution chart, Cocrystal Pharma ranks #35 out of 699 companies in the Biotechnology industry, placing it in the top 5%.
Is Cocrystal Pharma's Cyclically Adjusted PB Ratio too high?
Cocrystal Pharma's current Cyclically Adjusted PB Ratio of 0.04 is 60% below median its 10-year median of 0.10. Over the past 10 years, this metric has ranged from a low of 0.03 to a high of 1.39. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.66. Cocrystal Pharma's value of 0.04 is 97.6% below this industry median. Based on the distribution chart, Cocrystal Pharma ranks #35 out of 699 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Cocrystal Pharma has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Cocrystal Pharma's Cyclically Adjusted PB Ratio compare to HOOK and LNAI?
According to the Biotechnology industry distribution chart, Cocrystal Pharma ranks #35 out of 699 companies for Cyclically Adjusted PB Ratio. This places Cocrystal Pharma in the top 5% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.66. Cocrystal Pharma's value of 0.04 is 97.6% below this benchmark. Historically, Cocrystal Pharma's own Cyclically Adjusted PB Ratio has ranged from 0.03 to 1.39 over the past decade. While the company's 10-year median is 0.10 vs. the industry median of 1.66, Cocrystal Pharma has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.66, based on 699 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Cocrystal Pharma's current Cyclically Adjusted PB Ratio of 0.04 is 97.6% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Cocrystal Pharma and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.66 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Cocrystal Pharma's current Cyclically Adjusted PB Ratio is 0.04, which is 60% below median its own 10-year median of 0.10. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cocrystal Pharma stock overvalued right now?
Cocrystal Pharma (COCP) has a current Cyclically Adjusted PB Ratio of 0.04. The current Cyclically Adjusted PB Ratio is 0.04, which is 60% below median its 10-year median of 0.10 and 97.6% below the Biotechnology industry median of 1.66. Cocrystal Pharma's overall GF Score™ is 23/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Cocrystal Pharma (COCP), the current Cyclically Adjusted PB Ratio is 0.04 as of Jul. 11, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Cocrystal Pharma Business Description

Other Exchanges 8CC:Germany
Address 19805 North Creek Parkway, Bothell, WA, USA, 98011
Cocrystal Pharma Inc is a biotechnology company discovering and developing novel antiviral therapeutics that target the replication machinery of influenza viruses, hepatitis C viruses, and noroviruses. It employs structure-based technologies and Nobel Prize-winning expertise to create first and in-class antiviral drugs. It is developing CC-31244, an investigational, oral, broad-spectrum replication inhibitor called a non-nucleoside inhibitor (NNI). The company has one reportable and operating segment dedicated to the research and development company's novel orally administered antiviral influenza candidate. The company has pipeline products for diseases like : Influenza, Norovirus, Coronavirus, Respiratory Viruses, and Hepatitis C.
23GF Score

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