ENTX (Entera Bio) Cyclically Adjusted PB Ratio: 291.00 (As of Aug. 17, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ENTX Entera Bio Ltd ENTX
26 GF Score
Price $2.91
! 4 Warning Signs
View Full Analysis

What is Entera Bio Cyclically Adjusted PB Ratio?

Entera Bio ENTX +0.70% 26 Cyclically Adjusted PB Ratio is 291.00 as of Aug. 17, 2026. GuruFocus rates ENTX with a GF Score™ of 26/100. The stock has 4 warning signs investors should review. Among 693 Biotechnology companies, Entera Bio ranks worse than 99.86% on this metric.

As of today (2026-08-17), Entera Bio's current share price is $2.91. Entera Bio's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $0.01. Entera Bio's Cyclically Adjusted PB Ratio for today is 291.00.

The historical rank and industry rank for Entera Bio's Cyclically Adjusted PB Ratio or its related term are showing as below:

ENTX' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0   Med: 0   Max: 286.52
Current: 286.52

During the past years, Entera Bio's highest Cyclically Adjusted PB Ratio was 286.52. The lowest was 0.00. And the median was 0.00.

ENTX's Cyclically Adjusted PB Ratio is ranked worse than
99.86% of 693 companies
in the Biotechnology industry
Industry Median: 1.64 vs ENTX: 286.52

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Entera Bio's adjusted book value per share data for the three months ended in Jun. 2026 was $0.147. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $0.01 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Entera Bio  (NAS:ENTX) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Entera Bio Cyclically Adjusted PB Ratio Related Terms


Entera Bio Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Entera Bio's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Entera Bio Cyclically Adjusted PB Ratio Chart

Entera Bio Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

Entera Bio Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 174.27

ENTX vs ICCC, BDTX, COYA: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Entera Bio's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Entera Bio Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Entera Bio's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Entera Bio's Cyclically Adjusted PB Ratio falls into.


ENTX
26GF Score
Entera Bio Ltd ENTX
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Entera Bio Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Entera Bio's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=2.91/0.01
=291.00

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Entera Bio's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Entera Bio's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.147/333.9520*333.9520
=0.147

Current CPI (Jun. 2026) = 333.9520.

Entera Bio Quarterly Data

Book Value per Share CPI Adj_Book
201606 0.000 241.018 0.000
201609 0.000 241.428 0.000
201612 -2.209 241.432 -3.056
201706 -2.342 244.955 -3.193
201709 -2.506 246.819 -3.391
201712 -2.761 246.524 -3.740
201803 0.000 249.554 0.000
201806 -2.936 251.989 -3.891
201809 1.090 252.439 1.442
201812 0.883 251.233 1.174
201903 0.669 254.202 0.879
201906 0.544 256.143 0.709
201909 0.332 256.759 0.432
201912 0.667 256.974 0.867
202003 0.549 258.115 0.710
202006 0.396 257.797 0.513
202009 0.313 260.280 0.402
202012 0.357 260.474 0.458
202103 0.320 264.877 0.403
202106 0.895 271.696 1.100
202109 0.903 274.310 1.099
202112 0.783 278.802 0.938
202203 0.685 287.504 0.796
202206 0.599 296.311 0.675
202209 0.497 296.808 0.559
202212 0.408 296.797 0.459
202303 0.350 301.836 0.387
202306 0.286 305.109 0.313
202309 0.216 307.789 0.234
202312 0.293 306.746 0.319
202403 0.249 312.332 0.266
202406 0.235 314.175 0.250
202409 0.177 315.301 0.187
202412 0.208 315.605 0.220
202503 0.427 319.799 0.446
202506 0.380 322.561 0.393
202509 0.334 324.800 0.343
202512 0.284 324.054 0.293
202603 0.229 330.213 0.232
202606 0.147 333.952 0.147

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 291.00 mean?
Entera Bio (ENTX) has a Cyclically Adjusted PB Ratio of 291.00 as of Aug. 17, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Entera Bio and its competitors. According to the industry distribution chart, Entera Bio ranks #692 out of 693 companies in the Biotechnology industry, placing it in the top 99.9%.
Is Entera Bio's Cyclically Adjusted PB Ratio too high?
Entera Bio's current Cyclically Adjusted PB Ratio is 291.00. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.64. Entera Bio's value of 291.00 is 17643.9% above this industry median. Based on the distribution chart, Entera Bio ranks #692 out of 693 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Entera Bio has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.
How does Entera Bio's Cyclically Adjusted PB Ratio compare to ICCC and BDTX?
According to the Biotechnology industry distribution chart, Entera Bio ranks #692 out of 693 companies for Cyclically Adjusted PB Ratio. This places Entera Bio in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.64. Entera Bio's value of 291.00 is 17643.9% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.64, based on 693 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Entera Bio's current Cyclically Adjusted PB Ratio of 291.00 is 17643.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Entera Bio and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Entera Bio's current Cyclically Adjusted PB Ratio is 291.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Entera Bio stock overvalued right now?
Entera Bio (ENTX) has a current Cyclically Adjusted PB Ratio of 291.00. The current Cyclically Adjusted PB Ratio is 291.00 and 17643.9% above the Biotechnology industry median of 1.64. Entera Bio's overall GF Score™ is 26/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Entera Bio (ENTX), the current Cyclically Adjusted PB Ratio is 291.00 as of Aug. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Entera Bio Business Description

Other Exchanges 5DT:Germany
Address Kiryat Hadassah, Minrav Building - Fifth Floor, Hadassah Bio Park, Jerusalem, ISR, 9112002
Entera Bio Ltd is a clinical-stage biopharmaceutical company engaged in the development of orally delivered macromolecule therapeutics, including peptides and therapeutic proteins. The company focuses on underserved, chronic medical conditions where oral administration of a mini tablet peptide or peptide replacement therapy has the potential to perform. Its product candidates are: EB613, which is being developed as an oral, osteoanabolic (bone-building) tablet treatment for osteoporosis; EB612, being developed as an oral PTH(1-34) tablet peptide replacement therapy for patients with hypoparathyroidism; EB618, an Oral GLP-1 being developed to tackle obesity; and Oral GLP-2, a peptide tablet alternative for patients suffering from short bowel syndrome. The company operates in Israel.
26GF Score

Get the complete analysis for ENTX

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.91
Price