FENC (Fennec Pharmaceuticals) Cyclically Adjusted PB Ratio: 18.97 (As of Aug. 24, 2026) — 22% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FENC Fennec Pharmaceuticals Inc FENC
54 GF Score
Price $11.38
GF Value $10.77
Valuation Fairly Valued
! 1 Warning Sign
View Full Analysis

What is Fennec Pharmaceuticals Cyclically Adjusted PB Ratio?

Fennec Pharmaceuticals FENC +0.97% 54 Cyclically Adjusted PB Ratio is 18.97 as of Aug. 24, 2026, which is 22% above its 10-year median of 15.55. GuruFocus rates FENC with a GF Scoreâ„¢ of 54/100 and a GF Valueâ„¢ of $10.77 (Fairly Valued). The stock has 1 warning sign investors should review. Among 685 Biotechnology companies, Fennec Pharmaceuticals ranks worse than 93.28% on this metric.

As of today (2026-08-24), Fennec Pharmaceuticals's current share price is $11.38. Fennec Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was $0.60. Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio for today is 18.97.

The historical rank and industry rank for Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio or its related term are showing as below:

FENC' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 7.43   Med: 15.55   Max: 23.75
Current: 18

During the past years, Fennec Pharmaceuticals's highest Cyclically Adjusted PB Ratio was 23.75. The lowest was 7.43. And the median was 15.55.

FENC's Cyclically Adjusted PB Ratio is ranked worse than
93.28% of 685 companies
in the Biotechnology industry
Industry Median: 1.62 vs FENC: 18.00

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Fennec Pharmaceuticals's adjusted book value per share data for the three months ended in Jun. 2026 was $1.211. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $0.60 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Fennec Pharmaceuticals  (NAS:FENC) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Related Terms


Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Chart

Fennec Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 9.33 19.78 21.59 11.77 13.71

Fennec Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 15.14 17.52 13.71 10.11 17.80

FENC vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Fennec Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


FENC
54GF Score
Fennec Pharmaceuticals Inc FENC
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=11.38/0.60
=18.97

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Fennec Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Fennec Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=1.211/333.9520*333.9520
=1.211

Current CPI (Jun. 2026) = 333.9520.

Fennec Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201609 0.309 241.428 0.427
201612 0.262 241.432 0.362
201703 0.210 243.801 0.288
201706 0.619 244.955 0.844
201709 0.559 246.819 0.756
201712 1.453 246.524 1.968
201803 1.388 249.554 1.857
201806 1.323 251.989 1.753
201809 1.197 252.439 1.584
201812 1.071 251.233 1.424
201903 0.965 254.202 1.268
201906 0.828 256.143 1.080
201909 0.754 256.759 0.981
201912 0.597 256.974 0.776
202003 0.425 258.115 0.550
202006 1.425 257.797 1.846
202009 1.208 260.280 1.550
202012 1.118 260.474 1.433
202103 0.959 264.877 1.209
202106 0.857 271.696 1.053
202109 0.731 274.310 0.890
202112 0.606 278.802 0.726
202203 0.481 287.504 0.559
202206 0.328 296.311 0.370
202209 0.107 296.808 0.120
202212 -0.097 296.797 -0.109
202303 -0.278 301.836 -0.308
202306 -0.367 305.109 -0.402
202309 -0.399 307.789 -0.433
202312 -0.430 306.746 -0.468
202403 0.111 312.332 0.119
202406 -0.050 314.175 -0.053
202409 -0.189 315.301 -0.200
202412 -0.213 315.605 -0.225
202503 -0.213 319.799 -0.222
202506 -0.269 322.561 -0.278
202509 -0.160 324.800 -0.165
202512 1.038 324.054 1.070
202603 1.091 330.213 1.103
202606 1.211 333.952 1.211

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 18.97 mean?
Fennec Pharmaceuticals (FENC) has a Cyclically Adjusted PB Ratio of 18.97 as of Aug. 24, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Fennec Pharmaceuticals and its competitors. This is 22% above median its historical median of 15.55. Over the past decade, Fennec Pharmaceuticals' Cyclically Adjusted PB Ratio has ranged from 7.43 to 23.75. According to the industry distribution chart, Fennec Pharmaceuticals ranks #639 out of 685 companies in the Biotechnology industry, placing it in the top 93.3%.
Is Fennec Pharmaceuticals' Cyclically Adjusted PB Ratio too high?
Fennec Pharmaceuticals' current Cyclically Adjusted PB Ratio of 18.97 is 22% above median its 10-year median of 15.55. Over the past 10 years, this metric has ranged from a low of 7.43 to a high of 23.75. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Fennec Pharmaceuticals' value of 18.97 is 1071% above this industry median. Based on the distribution chart, Fennec Pharmaceuticals ranks #639 out of 685 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Fennec Pharmaceuticals has a GF Scoreâ„¢ of 54/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Fennec Pharmaceuticals' Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Fennec Pharmaceuticals ranks #639 out of 685 companies for Cyclically Adjusted PB Ratio. This places Fennec Pharmaceuticals in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Fennec Pharmaceuticals' value of 18.97 is 1071% above this benchmark. Historically, Fennec Pharmaceuticals' own Cyclically Adjusted PB Ratio has ranged from 7.43 to 23.75 over the past decade. While the company's 10-year median is 15.55 vs. the industry median of 1.62, Fennec Pharmaceuticals has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 685 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Fennec Pharmaceuticals's current Cyclically Adjusted PB Ratio of 18.97 is 1071% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Fennec Pharmaceuticals and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Fennec Pharmaceuticals's current Cyclically Adjusted PB Ratio is 18.97, which is 22% above median its own 10-year median of 15.55. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Fennec Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Fennec Pharmaceuticals (FENC) is currently considered Fairly Valued. The stock's GF Value™ is $10.77, compared to a current price of $11.38 — trading 5.7% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 18.97, which is 22% above median its 10-year median of 15.55 and 1071% above the Biotechnology industry median of 1.62. Fennec Pharmaceuticals' overall GF Score™ is 54/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Fennec Pharmaceuticals (FENC), the current Cyclically Adjusted PB Ratio is 18.97 as of Aug. 24, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Fennec Pharmaceuticals (FENC) Overvalued in 2026?

Based on GuruFocus' analysis, Fennec Pharmaceuticals stock appears to be overvalued. The current stock price of $11.38 is trading 5.7% above its estimated GF Value™ of $10.77. GuruFocus considers Fennec Pharmaceuticals to be Fairly Valued.

Key valuation signals for FENC:

  • Cyclically Adjusted PB Ratio: 18.97 (22% above median its 10-year median of 15.55)
  • GF Value™: $10.77 vs. price of $11.38 (5.7% above fair value)
  • GF Score™: 54/100 with 1 warning sign
  • Industry Position: 1071% above the Biotechnology median (#639 of 685)

No single metric tells the full story. See the FENC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Fennec Pharmaceuticals Business Description

Other Exchanges RV41:GermanyFRX:Canada
Address 68 TW Alexander Drive, PO Box 13628, Research Triangle Park, NC, USA, 27709
Fennec Pharmaceuticals Inc is a commercial-stage biopharmaceutical company. Its product candidate is PEDMARK which is sodium thiosulfate in a novel formulation for the prevention of cisplatin-induced hearing loss, or ototoxicity in children. The company principally operates in the United States.
54GF Score

Get the complete analysis for FENC

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$11.38
Price
$10.77
GF Value