Cosciens Biopharma (FRA:ET80) Cyclically Adjusted PB Ratio: 0.19 (As of Aug. 26, 2026) — 94% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FRA:ET80 Cosciens Biopharma Inc FRA:ET80
67 GF Score
Price €4.38
GF Value €5.20
Valuation Modestly Undervalued
! 4 Warning Signs
View Full Analysis

What is Cosciens Biopharma Cyclically Adjusted PB Ratio?

Cosciens Biopharma FRA:ET80 -1.13% 67 Cyclically Adjusted PB Ratio is 0.19 as of Aug. 26, 2026, which is 94% below its 10-year median of 3.05. GuruFocus rates FRA:ET80 with a GF Score™ of 67/100 and a GF Value™ of €5.20 (Modestly Undervalued). The stock has 4 warning signs investors should review. Among 684 Biotechnology companies, Cosciens Biopharma ranks better than 84.8% on this metric.

As of today (2026-08-26), Cosciens Biopharma's current share price is €4.38. Cosciens Biopharma's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was €22.81. Cosciens Biopharma's Cyclically Adjusted PB Ratio for today is 0.19.

The historical rank and industry rank for Cosciens Biopharma's Cyclically Adjusted PB Ratio or its related term are showing as below:

FRA:ET80' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.08   Med: 3.05   Max: 115.56
Current: 0.17

During the past years, Cosciens Biopharma's highest Cyclically Adjusted PB Ratio was 115.56. The lowest was 0.08. And the median was 3.05.

FRA:ET80's Cyclically Adjusted PB Ratio is ranked better than
84.8% of 684 companies
in the Biotechnology industry
Industry Median: 1.61 vs FRA:ET80: 0.17

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Cosciens Biopharma's adjusted book value per share data for the three months ended in Jun. 2026 was €12.935. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €22.81 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Cosciens Biopharma  (FRA:ET80) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Cosciens Biopharma Cyclically Adjusted PB Ratio Related Terms


Cosciens Biopharma Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Cosciens Biopharma's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cosciens Biopharma Cyclically Adjusted PB Ratio Chart

Cosciens Biopharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.04 2.33 0.63 0.28 0.20

Cosciens Biopharma Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.33 0.26 0.20 0.00 0.22

FRA:ET80 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Cosciens Biopharma's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cosciens Biopharma Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cosciens Biopharma's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Cosciens Biopharma's Cyclically Adjusted PB Ratio falls into.


FRA:ET80
67GF Score
Cosciens Biopharma Inc FRA:ET80
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Cosciens Biopharma Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Cosciens Biopharma's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=4.38/22.81
=0.19

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cosciens Biopharma's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Cosciens Biopharma's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=12.935/133.5265*133.5265
=12.935

Current CPI (Jun. 2026) = 133.5265.

Cosciens Biopharma Quarterly Data

Book Value per Share CPI Adj_Book
201609 24.738 101.765 32.459
201612 26.823 101.449 35.304
201703 27.404 102.634 35.653
201706 27.319 103.029 35.406
201709 27.445 103.345 35.460
201712 25.503 103.345 32.951
201803 23.638 105.004 30.059
201806 24.369 105.557 30.826
201809 24.861 105.636 31.425
201812 24.723 105.399 31.321
201903 24.804 106.979 30.959
201906 24.639 107.690 30.550
201909 24.954 107.611 30.963
201912 25.285 107.769 31.328
202003 24.578 107.927 30.408
202006 26.203 108.401 32.276
202009 25.779 108.164 31.824
202012 25.648 108.559 31.547
202103 27.065 110.298 32.765
202106 27.974 111.720 33.434
202109 28.812 112.905 34.074
202112 31.491 113.774 36.958
202203 34.769 117.646 39.462
202206 37.015 120.806 40.913
202209 38.267 120.648 42.352
202212 36.519 120.964 40.312
202303 35.917 122.702 39.085
202306 34.987 124.203 37.613
202309 33.529 125.230 35.750
202312 31.313 125.072 33.430
202403 28.722 126.258 30.376
202406 23.864 127.522 24.988
202409 17.323 127.285 18.172
202412 12.005 127.364 12.586
202503 8.945 129.181 9.246
202506 5.816 129.892 5.979
202509 4.079 130.287 4.180
202512 3.092 130.366 3.167
202603 0.000 132.262 0.000
202606 12.935 133.527 12.935

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.19 mean?
Cosciens Biopharma (FRA:ET80) has a Cyclically Adjusted PB Ratio of 0.19 as of Aug. 26, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Cosciens Biopharma and its competitors. This is 94% below median its historical median of 3.05. Over the past decade, Cosciens Biopharma's Cyclically Adjusted PB Ratio has ranged from 0.08 to 115.56. According to the industry distribution chart, Cosciens Biopharma ranks #104 out of 684 companies in the Biotechnology industry, placing it in the top 15.2%.
Is Cosciens Biopharma's Cyclically Adjusted PB Ratio too high?
Cosciens Biopharma's current Cyclically Adjusted PB Ratio of 0.19 is 94% below median its 10-year median of 3.05. Over the past 10 years, this metric has ranged from a low of 0.08 to a high of 115.56. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.61. Cosciens Biopharma's value of 0.19 is 88.2% below this industry median. Based on the distribution chart, Cosciens Biopharma ranks #104 out of 684 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Cosciens Biopharma has a GF Score™ of 67/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Cosciens Biopharma's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Cosciens Biopharma ranks #104 out of 684 companies for Cyclically Adjusted PB Ratio. This places Cosciens Biopharma in the top 15% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.61. Cosciens Biopharma's value of 0.19 is 88.2% below this benchmark. Historically, Cosciens Biopharma's own Cyclically Adjusted PB Ratio has ranged from 0.08 to 115.56 over the past decade. While the company's 10-year median is 3.05 vs. the industry median of 1.61, Cosciens Biopharma has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.61, based on 684 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Cosciens Biopharma's current Cyclically Adjusted PB Ratio of 0.19 is 88.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Cosciens Biopharma and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.61 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Cosciens Biopharma's current Cyclically Adjusted PB Ratio is 0.19, which is 94% below median its own 10-year median of 3.05. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cosciens Biopharma stock overvalued right now?
Based on GuruFocus' analysis, Cosciens Biopharma (FRA:ET80) is currently considered Modestly Undervalued. The stock's GF Value™ is €5.20, compared to a current price of €4.38 — trading 15.8% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.19, which is 94% below median its 10-year median of 3.05 and 88.2% below the Biotechnology industry median of 1.61. Cosciens Biopharma's overall GF Score™ is 67/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Cosciens Biopharma (FRA:ET80), the current Cyclically Adjusted PB Ratio is 0.19 as of Aug. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cosciens Biopharma (FRA:ET80) Overvalued in 2026?

Based on GuruFocus' analysis, Cosciens Biopharma stock appears to be undervalued. The current stock price of €4.38 is trading 15.8% below its estimated GF Value™ of €5.20. GuruFocus considers Cosciens Biopharma to be Modestly Undervalued.

Key valuation signals for FRA:ET80:

  • Cyclically Adjusted PB Ratio: 0.19 (94% below median its 10-year median of 3.05)
  • GF Value™: €5.20 vs. price of €4.38 (15.8% below fair value)
  • GF Score™: 67/100 with 4 warning signs
  • Industry Position: 88.2% below the Biotechnology median (#104 of 684)

No single metric tells the full story. See the FRA:ET80 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cosciens Biopharma Business Description

Other Exchanges CSCIF:USACSCI:Canada
Address C/o Borden Ladner Gervais Llp, Suite 3400, 22 Adelaide Street West, Toronto, ON, CAN, M5H 4E3
Cosciens Biopharma Inc is a biopharmaceutical company developing and commercializing pharmaceutical and diagnostic products and active ingredients for the healthcare and cosmetics industries. It operates through two segments: Active Ingredient and Biopharmaceutical. The Active Ingredient segment, which generates maximum revenue, focuses on plant-based ingredients derived from oats and other renewable resources, including oat beta glucan, oat oil, and avenanthramides. The Biopharmaceutical segment focuses on the development and commercialization of therapeutics and diagnostic tests, including its product Macrilen, and advancing a pre-clinical pipeline targeting unmet medical needs, particularly in rare or orphan indications. It operates in Canada, Germany, the United States, and Austria.
67GF Score

Get the complete analysis for FRA:ET80

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.38
Price
€5.20
GF Value