Fennec Pharmaceuticals (FRA:RV41) Cyclically Adjusted PB Ratio: 17.55 (As of Aug. 06, 2026) — 13% Above Median

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FRA:RV41 Fennec Pharmaceuticals Inc FRA:RV41
39 GF Score
Price €8.95
! 2 Warning Signs
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What is Fennec Pharmaceuticals Cyclically Adjusted PB Ratio?

Fennec Pharmaceuticals FRA:RV41 +2.87% 39 Cyclically Adjusted PB Ratio is 17.55 as of Aug. 06, 2026, which is 13% above its 10-year median of 15.52. GuruFocus rates FRA:RV41 with a GF Score™ of 39/100. The stock has 2 warning signs investors should review. Among 695 Biotechnology companies, Fennec Pharmaceuticals ranks worse than 92.95% on this metric.

As of today (2026-08-06), Fennec Pharmaceuticals's current share price is €8.95. Fennec Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €0.51. Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio for today is 17.55.

The historical rank and industry rank for Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio or its related term are showing as below:

FRA:RV41' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 7.43   Med: 15.52   Max: 23.75
Current: 18.06

During the past years, Fennec Pharmaceuticals's highest Cyclically Adjusted PB Ratio was 23.75. The lowest was 7.43. And the median was 15.52.

FRA:RV41's Cyclically Adjusted PB Ratio is ranked worse than
92.95% of 695 companies
in the Biotechnology industry
Industry Median: 1.58 vs FRA:RV41: 18.06

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Fennec Pharmaceuticals's adjusted book value per share data for the three months ended in Mar. 2026 was €0.943. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €0.51 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Fennec Pharmaceuticals  (FRA:RV41) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Related Terms


Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Chart

Fennec Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 9.33 19.78 21.59 11.77 13.71

Fennec Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 12.23 15.14 17.52 13.71 10.11

FRA:RV41 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Fennec Pharmaceuticals Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio falls into.


FRA:RV41
39GF Score
Fennec Pharmaceuticals Inc FRA:RV41
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Fennec Pharmaceuticals Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Fennec Pharmaceuticals's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=8.95/0.51
=17.55

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Fennec Pharmaceuticals's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Fennec Pharmaceuticals's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.943/330.2130*330.2130
=0.943

Current CPI (Mar. 2026) = 330.2130.

Fennec Pharmaceuticals Quarterly Data

Book Value per Share CPI Adj_Book
201606 0.304 241.018 0.417
201609 0.276 241.428 0.377
201612 0.248 241.432 0.339
201703 0.196 243.801 0.265
201706 0.551 244.955 0.743
201709 0.469 246.819 0.627
201712 1.228 246.524 1.645
201803 1.126 249.554 1.490
201806 1.132 251.989 1.483
201809 1.025 252.439 1.341
201812 0.942 251.233 1.238
201903 0.854 254.202 1.109
201906 0.733 256.143 0.945
201909 0.685 256.759 0.881
201912 0.537 256.974 0.690
202003 0.385 258.115 0.493
202006 1.265 257.797 1.620
202009 1.026 260.280 1.302
202012 0.919 260.474 1.165
202103 0.805 264.877 1.004
202106 0.711 271.696 0.864
202109 0.621 274.310 0.748
202112 0.537 278.802 0.636
202203 0.437 287.504 0.502
202206 0.310 296.311 0.345
202209 0.108 296.808 0.120
202212 -0.092 296.797 -0.102
202303 -0.260 301.836 -0.284
202306 -0.339 305.109 -0.367
202309 -0.374 307.789 -0.401
202312 -0.394 306.746 -0.424
202403 0.102 312.332 0.108
202406 -0.046 314.175 -0.048
202409 -0.170 315.301 -0.178
202412 -0.204 315.605 -0.213
202503 -0.197 319.799 -0.203
202506 -0.233 322.561 -0.239
202509 -0.136 324.800 -0.138
202512 0.887 324.054 0.904
202603 0.943 330.213 0.943

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 17.55 mean?
Fennec Pharmaceuticals (FRA:RV41) has a Cyclically Adjusted PB Ratio of 17.55 as of Aug. 06, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Fennec Pharmaceuticals and its competitors. This is 13% above median its historical median of 15.52. Over the past decade, Fennec Pharmaceuticals' Cyclically Adjusted PB Ratio has ranged from 7.43 to 23.75. According to the industry distribution chart, Fennec Pharmaceuticals ranks #646 out of 695 companies in the Biotechnology industry, placing it in the top 92.9%.
Is Fennec Pharmaceuticals' Cyclically Adjusted PB Ratio too high?
Fennec Pharmaceuticals' current Cyclically Adjusted PB Ratio of 17.55 is 13% above median its 10-year median of 15.52. Over the past 10 years, this metric has ranged from a low of 7.43 to a high of 23.75. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.58. Fennec Pharmaceuticals' value of 17.55 is 1010.8% above this industry median. Based on the distribution chart, Fennec Pharmaceuticals ranks #646 out of 695 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Fennec Pharmaceuticals has a GF Score™ of 39/100, reflecting its overall financial health beyond just this single metric.
How does Fennec Pharmaceuticals' Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Fennec Pharmaceuticals ranks #646 out of 695 companies for Cyclically Adjusted PB Ratio. This places Fennec Pharmaceuticals in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.58. Fennec Pharmaceuticals' value of 17.55 is 1010.8% above this benchmark. Historically, Fennec Pharmaceuticals' own Cyclically Adjusted PB Ratio has ranged from 7.43 to 23.75 over the past decade. While the company's 10-year median is 15.52 vs. the industry median of 1.58, Fennec Pharmaceuticals has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.58, based on 695 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Fennec Pharmaceuticals's current Cyclically Adjusted PB Ratio of 17.55 is 1010.8% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Fennec Pharmaceuticals and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.58 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Fennec Pharmaceuticals's current Cyclically Adjusted PB Ratio is 17.55, which is 13% above median its own 10-year median of 15.52. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Fennec Pharmaceuticals stock overvalued right now?
Fennec Pharmaceuticals (FRA:RV41) has a current Cyclically Adjusted PB Ratio of 17.55. The current Cyclically Adjusted PB Ratio is 17.55, which is 13% above median its 10-year median of 15.52 and 1010.8% above the Biotechnology industry median of 1.58. Fennec Pharmaceuticals' overall GF Score™ is 39/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Fennec Pharmaceuticals (FRA:RV41), the current Cyclically Adjusted PB Ratio is 17.55 as of Aug. 06, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Fennec Pharmaceuticals Business Description

Address 68 TW Alexander Drive, PO Box 13628, Research Triangle Park, NC, USA, 27709
Fennec Pharmaceuticals Inc is a commercial-stage biopharmaceutical company. Its product candidate is PEDMARK which is sodium thiosulfate in a novel formulation for the prevention of cisplatin-induced hearing loss, or ototoxicity in children. The company principally operates in the United States.
39GF Score

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Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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